Genular: Defining Cellular Identity and Function

Details for: Nedd8

Gene ID: 18002

Symbol: Nedd8

Ensembl ID: ENSMUSG00000010376

Description: neural precursor cell expressed, developmentally down-regulated gene 8

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Deubiquitination
(R-MMU-5688426)
Iron uptake and transport
(R-MMU-917937)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Neddylation
(R-MMU-8951664)
Post-translational protein modification
(R-MMU-597592)
Signaling by tgf-beta receptor complex
(R-MMU-170834)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Tgf-beta receptor signaling activates smads
(R-MMU-2173789)
Transport of small molecules
(R-MMU-382551)
Uch proteinases
(R-MMU-5689603)
Vesicle-mediated transport
(R-MMU-5653656)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Modification-dependent protein catabolic process
(GO:0019941)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein localization
(GO:0008104)
Protein neddylation
(GO:0045116)
Protein tag activity
(GO:0031386)
Protein ubiquitination
(GO:0016567)
Regulation of proteolysis
(GO:0030162)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to organic cyclic compound
(GO:0014070)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

NEDD8

Genular Protein ID: 256996056

Symbol: NEDD8_MOUSE

Name: NEDD8

UniProtKB Accession Codes:

P29595

Database IDs:

Citations:

PubMed ID: 1378265

Title: Identification of a set of genes with developmentally down-regulated expression in the mouse brain.

PubMed ID: 1378265

DOI: 10.1016/0006-291x(92)91747-e

PubMed ID: 8395831

Title: Cloning of a cDNA which encodes a novel ubiquitin-like protein.

PubMed ID: 8395831

DOI: 10.1006/bbrc.1993.2056

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9353319

Title: Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein.

PubMed ID: 9353319

DOI: 10.1074/jbc.272.45.28557

PubMed ID: 10597293

Title: Covalent modification of all members of human cullin family proteins by NEDD8.

PubMed ID: 10597293

DOI: 10.1038/sj.onc.1203093

PubMed ID: 11696557

Title: The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice.

PubMed ID: 11696557

DOI: 10.1083/jcb.200104035

PubMed ID: 12215427

Title: Interaction with Nedd8, a ubiquitin-like protein, enhances the transcriptional activity of the aryl hydrocarbon receptor.

PubMed ID: 12215427

DOI: 10.1074/jbc.m202413200

PubMed ID: 15183309

Title: Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8.

PubMed ID: 15183309

DOI: 10.1016/j.modgep.2004.01.005

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 81
Mass: 8972
Checksum: DC339102BE4725D2
Sequence:

MLIKVKTLTG KEIEIDIEPT DKVERIKERV EEKEGIPPQQ QRLIYSGKQM NDEKTAADYK 
ILGGSVLHLV LALRGGGGLG Q

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nedd8

Associated with

Other Information

Identification of a set of genes with developmentally down-regulated expression in the mouse brain. PubMed ID: 1378265

Cloning of a cDNA which encodes a novel ubiquitin-like protein. PubMed ID: 8395831

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein. PubMed ID: 9353319

Covalent modification of all members of human cullin family proteins by NEDD8. PubMed ID: 10597293

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. PubMed ID: 11696557

Interaction with Nedd8, a ubiquitin-like protein, enhances the transcriptional activity of the aryl hydrocarbon receptor. PubMed ID: 12215427

Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8. PubMed ID: 15183309

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337