Genular: Defining Cellular Identity and Function

Details for: Neurod2

Gene ID: 18013

Symbol: Neurod2

Ensembl ID: ENSMUSG00000038255

Description: neurogenic differentiation 2

Associated with

Associative learning
(GO:0008306)
Axon development
(GO:0061564)
Behavioral fear response
(GO:0001662)
Cell differentiation
(GO:0030154)
Cellular response to calcium ion
(GO:0071277)
Cellular response to electrical stimulus
(GO:0071257)
Cerebellar cortex development
(GO:0021695)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Multicellular organism development
(GO:0007275)
Negative regulation of synapse maturation
(GO:2000297)
Nervous system development
(GO:0007399)
Neuron development
(GO:0048666)
Nucleus
(GO:0005634)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of synapse maturation
(GO:0090129)
Positive regulation of synaptic plasticity
(GO:0031915)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein heterodimerization activity
(GO:0046982)
Protein ubiquitination
(GO:0016567)
Regulation of dna-templated transcription
(GO:0006355)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sensory organ development
(GO:0007423)
Sequence-specific double-stranded dna binding
(GO:1990837)

Other Information

Proteins

Neurogenic differentiation factor 2

Genular Protein ID: 3723397419

Symbol: NDF2_MOUSE

Name: Neurogenic differentiation factor 2

UniProtKB Accession Codes:

Q62414 Q61952 Q925V5

Database IDs:

Citations:

PubMed ID: 8816493

Title: NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.

PubMed ID: 8816493

DOI: 10.1128/mcb.16.10.5792

PubMed ID: 8607837

Title: Molecular cloning and characterization of a cDNA encoding a novel basic helix-loop-helix protein structurally related to Neuro-D/BHF1.

PubMed ID: 8607837

DOI: 10.1006/bbrc.1996.0476

PubMed ID: 10814830

Title: Structure of the mouse NDRF gene and its regulation during neuronal differentiation of P19 cells.

PubMed ID: 10814830

DOI: 10.1016/s0169-328x(00)00038-3

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10648228

Title: Generation of neurons by transient expression of neural bHLH proteins in mammalian cells.

PubMed ID: 10648228

DOI: 10.1242/dev.127.4.693

PubMed ID: 11356028

Title: NeuroD2 is necessary for development and survival of central nervous system neurons.

PubMed ID: 11356028

DOI: 10.1006/dbio.2001.0245

PubMed ID: 14697366

Title: Regulation of neuroD2 expression in mouse brain.

PubMed ID: 14697366

DOI: 10.1016/j.ydbio.2003.08.027

PubMed ID: 16203979

Title: The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning.

PubMed ID: 16203979

DOI: 10.1073/pnas.0506785102

PubMed ID: 16504944

Title: Regulation of thalamocortical patterning and synaptic maturation by NeuroD2.

PubMed ID: 16504944

DOI: 10.1016/j.neuron.2006.01.031

PubMed ID: 16730830

Title: Transduction of NeuroD2 protein induced neural cell differentiation.

PubMed ID: 16730830

DOI: 10.1016/j.jbiotec.2006.04.021

PubMed ID: 18214987

Title: E protein dosage influences brain development more than family member identity.

PubMed ID: 18214987

DOI: 10.1002/jnr.21615

PubMed ID: 19900895

Title: A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation.

PubMed ID: 19900895

DOI: 10.1126/science.1177087

PubMed ID: 20346398

Title: Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation.

PubMed ID: 20346398

DOI: 10.1016/j.mcn.2010.03.006

Sequence Information:

Length: 383
Mass: 41493
Checksum: 68342005219829B1
Sequence:

MLTRLFSEPG LLSDVPKFAS WGDGDDDEPR SDKGDAPPQP PPAPGSGAPG PARAAKPVSL 
RGGEEIPEPT LAEVKEEGEL GGEEEEEEEE EEGLDEAEGE RPKKRGPKKR KMTKARLERS 
KLRRQKANAR ERNRMHDLNA ALDNLRKVVP CYSKTQKLSK IETLRLAKNY IWALSEILRS 
GKRPDLVSYV QTLCKGLSQP TTNLVAGCLQ LNSRNFLTEQ GADGAGRFHG SGGPFAMHPY 
PYPCSRLAGA QCQAAGGLGG GAAHALRTHG YCAAYETLYA AAGGGGASPD YNSSEYEGPL 
SPPLCLNGNF SLKQDSSPDH EKSYHYSMHY SALPGSRPTG HGLVFGSSAV RGGVHSENLL 
SYDMHLHHDR GPMYEELNAF FHN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Neurod2

Associated with

Other Information

NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family. PubMed ID: 8816493

Molecular cloning and characterization of a cDNA encoding a novel basic helix-loop-helix protein structurally related to Neuro-D/BHF1. PubMed ID: 8607837

Structure of the mouse NDRF gene and its regulation during neuronal differentiation of P19 cells. PubMed ID: 10814830

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. PubMed ID: 10648228

NeuroD2 is necessary for development and survival of central nervous system neurons. PubMed ID: 11356028

Regulation of neuroD2 expression in mouse brain. PubMed ID: 14697366

The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning. PubMed ID: 16203979

Regulation of thalamocortical patterning and synaptic maturation by NeuroD2. PubMed ID: 16504944

Transduction of NeuroD2 protein induced neural cell differentiation. PubMed ID: 16730830

E protein dosage influences brain development more than family member identity. PubMed ID: 18214987

A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. PubMed ID: 19900895

Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation. PubMed ID: 20346398