Details for: Nfe2l1
Associated with
Other Information
Genular Protein ID: 4071261882
Symbol: NF2L1_MOUSE
Name: Nuclear factor, erythroid derived 2, like 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7759107
PubMed ID: 9580677
Title: A novel splice variant of the transcription factor Nrf1 interacts with the TNFalpha promoter and stimulates transcription.
PubMed ID: 9580677
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 9087432
Title: The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development.
PubMed ID: 9087432
DOI: 10.1101/gad.11.6.786
PubMed ID: 9501099
Title: Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.
PubMed ID: 9501099
PubMed ID: 10601325
Title: The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts.
PubMed ID: 10601325
PubMed ID: 11342101
Title: TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter.
PubMed ID: 11342101
PubMed ID: 12968018
Title: Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.
PubMed ID: 12968018
PubMed ID: 12808106
Title: Nrf1 is critical for redox balance and survival of liver cells during development.
PubMed ID: 12808106
PubMed ID: 15738389
Title: Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia.
PubMed ID: 15738389
PubMed ID: 16872277
Title: Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
PubMed ID: 16872277
DOI: 10.1042/bj20060725
PubMed ID: 17705787
Title: The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.
PubMed ID: 17705787
DOI: 10.1042/bj20070761
PubMed ID: 17510056
Title: Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.
PubMed ID: 17510056
PubMed ID: 18826952
Title: Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
PubMed ID: 18826952
PubMed ID: 18990090
Title: The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors.
PubMed ID: 18990090
DOI: 10.1042/bj20081575
PubMed ID: 20629635
Title: Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane.
PubMed ID: 20629635
DOI: 10.1042/bj20100471
PubMed ID: 20385086
Title: Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.
PubMed ID: 20385086
PubMed ID: 21554501
Title: Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.
PubMed ID: 21554501
PubMed ID: 21953459
Title: The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
PubMed ID: 21953459
PubMed ID: 21911472
Title: Dual regulation of the transcriptional activity of Nrf1 by beta-TrCP- and Hrd1-dependent degradation mechanisms.
PubMed ID: 21911472
DOI: 10.1128/mcb.05663-11
PubMed ID: 21536885
Title: Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration.
PubMed ID: 21536885
PubMed ID: 22586274
Title: NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1beta genes.
PubMed ID: 22586274
DOI: 10.1128/mcb.06706-11
PubMed ID: 23144760
Title: Characterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes.
PubMed ID: 23144760
PubMed ID: 23816881
Title: The casein kinase 2-nrf1 axis controls the clearance of ubiquitinated proteins by regulating proteasome gene expression.
PubMed ID: 23816881
DOI: 10.1128/mcb.01271-12
PubMed ID: 25041126
Title: Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice.
PubMed ID: 25041126
DOI: 10.1111/gtc.12165
PubMed ID: 26268886
Title: The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression.
PubMed ID: 26268886
DOI: 10.1038/srep12983
PubMed ID: 26947393
Title: Nuclear factor erythroid-2 like 1 (NFE2L1): structure, function and regulation.
PubMed ID: 26947393
PubMed ID: 29149604
Title: NRF1 is an ER membrane sensor that is central to cholesterol homeostasis.
PubMed ID: 29149604
Sequence Information:
- Length: 741
- Mass: 81575
- Checksum: DDB267F32CD2A92C
- Sequence:
MLSLKKYLTE GLLQFTILLS LIGVRVDVDT YLTSQLPPLR EIILGPSSAY TQTQFHNLRN TLDGYGIHPK SIDLDNYFTA RRLLSQVRAL DRFQVPTTEV NAWLVHRDPE GSVSGSQPNS GLALESSSGL QDVTGPDNGV RESETEQGFG EDLEDLGAVA PPVSGDLTKE DIDLIDILWR QDIDLGAGRE VFDYSHRQKE QDVDKELQDG REREDTWSGE GAEALARDLL VDGETGESFP AQFPADVSSI PEAVPSESES PALQNSLLSP LLTGTESPFD LEQQWQDLMS IMEMQAMEVN TSASEILYNA PPGDPLSTNY SLAPNTPINQ NVSLHQASLG GCSQDFSLFS PEVESLPVAS SSTLLPLVPS NSTSLNSTFG STNLAGLFFP SQLNGTANDT SGPELPDPLG GLLDEAMLDE ISLMDLAIEE GFNPVQASQL EEEFDSDSGL SLDSSHSPSS LSSSEGSSSS SSSSSSSSAS SSASSSFSEE GAVGYSSDSE TLDLEEAEGA VGYQPEYSKF CRMSYQDPSQ LSCLPYLEHV GHNHTYNMAP SALDSADLPP PSTLKKGSKE KQADFLDKQM SRDEHRARAM KIPFTNDKII NLPVEEFNEL LSKYQLSEAQ LSLIRDIRRR GKNKMAAQNC RKRKLDTILN LERDVEDLQR DKARLLREKV EFLRSLRQMK QKVQSLYQEV FGRLRDEHGR PYSPSQYALQ YAGDGSVLLI PRTMADQQAR RQERKPKDRR K
Genular Protein ID: 1988377622
Symbol: Q3U5L0_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
Sequence Information:
- Length: 741
- Mass: 81601
- Checksum: 1AAE16343557A05C
- Sequence:
MLSLKKYLTE GLLQFTILLS LIGVRVDVDT YLTSQLPPLR EIILGPSSAY TQTQFHNLRN TLDGYGIHPK SIDLDNYFTA RRLLSQVRAL DRFQVPTTEV NAWLVHRDPE GSVSGSQPNS GLALESSSGL QDVTGPDNGV RESETEQGFG EDLEDLGAVA PPVSGDLTKE DIDLIDILWR QDIDLGAGRE VFDYSHRQKE QDVDKELQDG REREDTWSGE GAEALARDLL VDGETGESFP AQFPADVSII PEAVPSESES PALQNSLLSP LLTGTESPFD LEQQWQDLMS IMEMQAMEVN TSASEILYNA PPGDPLSTNY SLAPNTPINQ NVSLHQASLG GCSQDFSLFS PEVESLPVAS SSTLLPLVPS NSTSLNSTFG STNLAGLFFP SQLNGTANDT SGPELPDPLG GLLDEAMLDE ISLMDLAIEE GFNPVQASQL EEEFDSDSGL SLDSSHSPSS LSSSEGSSSS SSSSSSSSAS SSASSSFSEE GAVGYSSDSE TLDLEEAEGA VGYQPEYSKF CRMSYQDPSQ LSCLPYLEHV GHNHTYNMAP SALDSADLPP PSTLKKGSKE KQADFLDKQM SRDEHRARAM KIPFTNDKII NLPVEEFNEL LSKYQLSEAQ LSLIRDIRRR GKNKMAAQNC RKRKLDTILN LERDVEDLQR DKARLLREKV EFLRSLRQMK QKVQSLYQEV FGRLRDEHGR PYSPSQYALQ YAGDGSVLLI PRTMADQQAR RQERKPKDRR K
Genular Protein ID: 2291676442
Symbol: Q3UFI8_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
Sequence Information:
- Length: 572
- Mass: 62887
- Checksum: E2E15EE0ABADC53A
- Sequence:
MGWESRLTAA SADIDLGAGR EVFDYSHRQK EQDVDKELQD GREREDTWSG EGAEALARDL LVDGETGESF PAQFPADVSS IPEAVPSESE SPALQNSLLS PLLTGTESPF DLEQQWQDLM SIMEMQAMEV NTSASEILYN APPGDPLSTN YSLAPNTPIN QNVSLHQASL GGCSQDFSLF SPEVESLPVA SSSTLLPLVP SNSTSLNSTF GSTNLAGLFF PSQLNGTAND TSGPELPDPL GGLLDEAMLD EISLMDLAIE EGFNPVQASQ LEEEFDSDSG LSLDSSHSPS SLSSSEGSSS SSSSSSSSSA SSSASSSFSE EGAVGYSSDS ETLDLEEAEG AVGYQPEYSK FCRMSYQDPS QLSCLPYLEH VGHNHTYNMA PSALDSADLP PPSTLKKGSK EKQADFLDKQ MSRDEHRARA MKIPFTNDKI INLPVEEFNE LLSKYQLSEA QLSLIRDIRR RGKNKMAAQN CRKRKLDTIL NLERDVEDLQ RDKARLLREK VEFLRSLRQM KQKVQSLYQE VFGRLRDEHG RPYSPSQYAL QYAGDGSVLL IPRTMADQQA RRQERKPKDR RK
Genular Protein ID: 3529989992
Symbol: Q3V3M1_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
Sequence Information:
- Length: 453
- Mass: 49852
- Checksum: 47EC7D2BD9AE123F
- Sequence:
MSIMEMQAME VNTSASEILY NAPPGDPLST NYSLAPNTPI NQNVSLHQAS LGGCSQDFSL FSPEVESLPV ASSSTLLPLV PSNSTSLNST FGSTNLAGLF FPSQLNGTAN DTSGPELPDP LGGLLDEAML DEISLMDLAI EEGFNPVQAS QLEEEFDSDS GLSLDSSHSP SSLSSSEGSS SSSSSSSSSS ASSSASSSFS EEGAVGYSSD SETLDLEEAE GAVGYQPEYS KFCRMSYQDP SQLSCLPYLE HVGHNHTYNM APSALDSADL PPPSTLKKGS KEKQADFLDK QMSRDEHRAR AMKIPFTNDK IINLPVEEFN ELLSKYQLSE AQLSLIRDIR RRGKNKMAAQ NCRKRKLDTI LNLERDVEDL QRDKARLLRE KVEFLRSLRQ MKQKVQSLYQ EVFGRLRDEH GRPYSPSQYA LQYAGDGSVL LIPRTMADQQ ARRQERKPKD RRK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.