Genular: Defining Cellular Identity and Function

Details for: Nfib

Gene ID: 18028

Symbol: Nfib

Ensembl ID: ENSMUSG00000008575

Description: nuclear factor I/B

Associated with

Anterior commissure morphogenesis
(GO:0021960)
Brain development
(GO:0007420)
Cell differentiation involved in salivary gland development
(GO:0060689)
Cell population proliferation
(GO:0008283)
Cell proliferation in forebrain
(GO:0021846)
Cell quiescence
(GO:0044838)
Cerebellar mossy fiber
(GO:0044300)
Chondrocyte differentiation
(GO:0002062)
Club cell differentiation
(GO:0060486)
Commissural neuron axon guidance
(GO:0071679)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Dna replication
(GO:0006260)
Double-stranded dna binding
(GO:0003690)
Exit from mitosis
(GO:0010458)
Fibrillar center
(GO:0001650)
Forebrain development
(GO:0030900)
Gene expression
(GO:0010467)
Generation of neurons
(GO:0048699)
Glandular epithelial cell differentiation
(GO:0002067)
Glial cell differentiation
(GO:0010001)
Glial cell fate specification
(GO:0021780)
Glial cell proliferation
(GO:0014009)
Hindbrain development
(GO:0030902)
Lung ciliated cell differentiation
(GO:0061141)
Lung development
(GO:0030324)
Negative regulation of dna binding
(GO:0043392)
Negative regulation of epithelial cell proliferation involved in lung morphogenesis
(GO:2000795)
Negative regulation of mesenchymal cell proliferation involved in lung development
(GO:2000791)
Negative regulation of mirna transcription
(GO:1902894)
Negative regulation of stem cell proliferation
(GO:2000647)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural precursor cell proliferation
(GO:0061351)
Neurogenesis
(GO:0022008)
Neuron fate specification
(GO:0048665)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Principal sensory nucleus of trigeminal nerve development
(GO:0021740)
Regeneration
(GO:0031099)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to bacterium
(GO:0009617)
Response to wounding
(GO:0009611)
Retina development in camera-type eye
(GO:0060041)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Salivary gland cavitation
(GO:0060662)
Sequence-specific double-stranded dna binding
(GO:1990837)
Stem cell population maintenance
(GO:0019827)
Stem cell proliferation
(GO:0072089)
Tissue homeostasis
(GO:0001894)
Transcription regulator inhibitor activity
(GO:0140416)
Type ii pneumocyte differentiation
(GO:0060510)
Type i pneumocyte differentiation
(GO:0060509)

Other Information

Proteins

Nuclear factor 1 B-type
Q6GSP7_MOUSE

Genular Protein ID: 2395780013

Symbol: NFIB_MOUSE

Name: Nuclear factor 1 B-type

UniProtKB Accession Codes:

P97863 P70252 P70253 P70254 Q9R1G4

Database IDs:

Citations:

PubMed ID: 9056636

Title: Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

PubMed ID: 9056636

DOI: 10.1002/(sici)1097-0177(199703)208:3<313::aid-aja3>3.0.co;2-l

PubMed ID: 12568726

Title: Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.

PubMed ID: 12568726

DOI: 10.1016/s0378-1119(02)01204-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10087299

Title: Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals.

PubMed ID: 10087299

DOI: 10.1007/s003359901008

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 15632069

Title: The transcription factor gene Nfib is essential for both lung maturation and brain development.

PubMed ID: 15632069

DOI: 10.1128/mcb.25.2.685-698.2005

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 30388402

Title: NFIB haploinsufficiency is associated with intellectual disability and macrocephaly.

PubMed ID: 30388402

DOI: 10.1016/j.ajhg.2018.10.006

Sequence Information:

Length: 570
Mass: 63507
Checksum: D94AB4400A2811CC
Sequence:

MMYSPICLTQ DEFHPFIEAL LPHVRAIAYT WFNLQARKRK YFKKHEKRMS KDEERAVKDE 
LLSEKPEIKQ KWASRLLAKL RKDIRQEYRE DFVLTVTGKK HPCCVLSNPD QKGKIRRIDC 
LRQADKVWRL DLVMVILFKG IPLESTDGER LMKSPHCTNP ALCVQPHHIT VSVKELDLFL 
AYYVQEQDSG QSGSPSHSDP AKNPPGYLED SFVKSGVFNV SELVRVSRTP ITQGTGVNFP 
IGEIPSQPYY HDMNSGVNLQ RSLSSPPSSK RPKTISIDEN MEPSPTGDFY PSPNSPAAGS 
RTWHERDQDM SSPTTMKKPE KPLFSSTSPQ DSSPRLSTFP QHHHPGIPGV AHSVISTRTP 
PPPSPLPFPT QAILPPAPSS YFSHPTIRYP PHLNPQDTLK NYVPSYDPSS PQTSQPNSSG 
QVVGKVPGHF TPVLAPSPHP SAVRPVTLTM TDTKPITTST EGEAASPTAT TYTASGTSQA 
NRYVGLSPRD PSFLHQQQLR ICDWTMNQNG RHLYPSTSED TLGITWQSPG TWASLVPFQV 
SNRTPILPAN VQNYGLNIIG EPFLQAETSN

Genular Protein ID: 1185143284

Symbol: Q6GSP7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q6GSP7

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 11978849

Title: Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.

PubMed ID: 11978849

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 420
Mass: 47472
Checksum: E26259E1F965146D
Sequence:

MMYSPICLTQ DEFHPFIEAL LPHVRAIAYT WFNLQARKRK YFKKHEKRMS KDEERAVKDE 
LLSEKPEIKQ KWASRLLAKL RKDIRQEYRE DFVLTVTGKK HPCCVLSNPD QKGKIRRIDC 
LRQADKVWRL DLVMVILFKG IPLESTDGER LMKSPHCTNP ALCVQPHHIT VSVKELDLFL 
AYYVQEQDSG QSGSPSHSDP AKNPPGYLED SFVKSGVFNV SELVRVSRTP ITQGTGVNFP 
IGEIPSQPYY HDMNSGVNLQ RSLSSPPSSK RPKTISIDEN MEPSPTGDFY PSPNSPAAGS 
RTWHERDQDM SSPTTMKKPE KPLFSSTSPQ DSSPRLSTFP QHHHPGIPGV AHSVISTRTP 
PPPSPLPFPT QAILPPAPSS YFSHPTIRYP PHLNPQDTLK NYVPSYDPSS PQTSQSWYLG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nfib

Associated with

Other Information

Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. PubMed ID: 9056636

Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One. PubMed ID: 12568726

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals. PubMed ID: 10087299

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

The transcription factor gene Nfib is essential for both lung maturation and brain development. PubMed ID: 15632069

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

NFIB haploinsufficiency is associated with intellectual disability and macrocephaly. PubMed ID: 30388402

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a &lt;1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene. PubMed ID: 11978849

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Database document:

PubMed ID: 9056636

PubMed ID: 12568726

PubMed ID: 15489334

PubMed ID: 10087299

PubMed ID: 15345747

PubMed ID: 15632069

PubMed ID: 17242355

PubMed ID: 21183079

PubMed ID: 23806337

PubMed ID: 24129315

PubMed ID: 30388402

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 11978849

PubMed ID: 12466851

PubMed ID: 15489334

PubMed ID: 16141073