Genular: Defining Cellular Identity and Function

Details for: Nfkbib

Gene ID: 18036

Symbol: Nfkbib

Ensembl ID: ENSMUSG00000030595

Description: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

Associated with

Activation of nf-kappab in b cells
(R-MMU-1169091)
Adaptive immune system
(R-MMU-1280218)
Cytokine signaling in immune system
(R-MMU-1280215)
Cytosolic sensors of pathogen-associated dna
(R-MMU-1834949)
Ddx58/ifih1-mediated induction of interferon-alpha/beta
(R-MMU-168928)
Downstream signaling events of b cell receptor (bcr)
(R-MMU-1168372)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-1 family signaling
(R-MMU-446652)
Interleukin-1 signaling
(R-MMU-9020702)
Myd88 cascade initiated on plasma membrane
(R-MMU-975871)
Myd88 dependent cascade initiated on endosome
(R-MMU-975155)
Myd88-independent tlr4 cascade
(R-MMU-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-MMU-166058)
Rip-mediated nfkb activation via zbp1
(R-MMU-1810476)
Signaling by interleukins
(R-MMU-449147)
Signaling by the b cell receptor (bcr)
(R-MMU-983705)
Tak1-dependent ikk and nf-kappa-b activation
(R-MMU-445989)
Toll-like receptor cascades
(R-MMU-168898)
Toll like receptor 2 (tlr2) cascade
(R-MMU-181438)
Toll like receptor 3 (tlr3) cascade
(R-MMU-168164)
Toll like receptor 4 (tlr4) cascade
(R-MMU-166016)
Toll like receptor 5 (tlr5) cascade
(R-MMU-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-MMU-168181)
Toll like receptor 9 (tlr9) cascade
(R-MMU-168138)
Toll like receptor 10 (tlr10) cascade
(R-MMU-168142)
Toll like receptor tlr1:tlr2 cascade
(R-MMU-168179)
Toll like receptor tlr6:tlr2 cascade
(R-MMU-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-MMU-975138)
Traf6 mediated nf-kb activation
(R-MMU-933542)
Trif(ticam1)-mediated tlr4 signaling
(R-MMU-937061)
Zbp1(dai) mediated induction of type i ifns
(R-MMU-1606322)
Cellular response to lipopolysaccharide
(GO:0071222)
Cytoplasm
(GO:0005737)
Inflammatory response
(GO:0006954)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of canonical nf-kappab signal transduction
(GO:0043122)

Other Information

Proteins

NF-kappa-B inhibitor beta

Genular Protein ID: 1205121949

Symbol: IKBB_MOUSE

Name: NF-kappa-B inhibitor beta

UniProtKB Accession Codes:

Q60778 Q564F1 Q9D6L5

Database IDs:

Citations:

PubMed ID: 7867065

Title: IkappaB-beta regulates the persistent response in a biphasic activation of NF-kappaB.

PubMed ID: 7867065

DOI: 10.1016/0092-8674(95)90511-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8816457

Title: Role of unphosphorylated, newly synthesized IkappaB beta in persistent activation of NF-kappaB.

PubMed ID: 8816457

DOI: 10.1128/mcb.16.10.5444

PubMed ID: 10657303

Title: A subclass of Ras proteins that regulate the degradation of IkappaB.

PubMed ID: 10657303

DOI: 10.1126/science.287.5454.869

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 359
Mass: 37965
Checksum: 0E2B46C89E2404EF
Sequence:

MAGVACLGKT ADADEWCDSG LGSLGPDAAA PGGPGLGAEL GPELSWAPLV FGYVTEDGDT 
ALHLAVIHQH EPFLDFLLGF SAGTEYLDLQ NDLGQTALHL AAILGEASTV EKLYAAGAGV 
LVAERGGHTA LHLACRVRAH TCACVLLQPR PSHPRDASDT YLTQSQDCTP DTSHAPAAVD 
SQPNPENEEE PRDEDWRLQL EAENYDGHTP LHVAVIHKDA EMVRLLRDAG ADLNKPEPTC 
GRTPLHLAVE AQAASVLELL LKAGADPTAR MYGGRTPLGS ALLRPNPILA RLLRAHGAPE 
PEDEDDKLSP CSSSGSDSDS DNRDEGDEYD DIVVHSGRSQ NRQPPSPASK PLPDDPNPA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nfkbib

Associated with

Other Information

IkappaB-beta regulates the persistent response in a biphasic activation of NF-kappaB. PubMed ID: 7867065

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Role of unphosphorylated, newly synthesized IkappaB beta in persistent activation of NF-kappaB. PubMed ID: 8816457