Details for: Nefl

Gene ID: 18039

Symbol: Nefl

Ensembl ID: ENSMUSG00000022055

Description: neurofilament, light polypeptide

Associated with

Other Information

Genular Protein ID: 380250093

Symbol: NFL_MOUSE

Name: Neurofilament light polypeptide

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3103856

Title: Cloning and developmental expression of the murine neurofilament gene family.

PubMed ID: 3103856

DOI: 10.1016/0169-328x(86)90030-6

PubMed ID: 3785173

Title: Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum.

PubMed ID: 3785173

DOI: 10.1128/mcb.6.5.1529-1534.1986

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2246261

Title: Structure of the 68-kDa neurofilament gene and regulation of its expression.

PubMed ID: 2246261

DOI: 10.1016/s0021-9258(17)45441-x

PubMed ID: 1717455

Title: Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport.

PubMed ID: 1717455

DOI: 10.1016/s0021-9258(18)55143-7

PubMed ID: 3919033

Title: Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: isolation of a cloned cDNA probe.

PubMed ID: 3919033

DOI: 10.1083/jcb.100.3.843

PubMed ID: 16236762

Title: RNA-binding protein is involved in aggregation of light neurofilament protein and is implicated in the pathogenesis of motor neuron degeneration.

PubMed ID: 16236762

DOI: 10.1093/hmg/ddi392

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 16452088

Title: O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

PubMed ID: 16452088

DOI: 10.1074/mcp.t500040-mcp200

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 18687884

Title: Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration.

PubMed ID: 18687884

DOI: 10.1073/pnas.0802261105

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22723690

Title: Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons.

PubMed ID: 22723690

DOI: 10.1523/jneurosci.1081-12.2012

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

  • Length: 543
  • Mass: 61508
  • Checksum: BC40F8A8A536CFF5
  • Sequence:
  • MSSFGYDPYF STSYKRRYVE TPRVHISSVR SGYSTARSAY SSYSAPVSSS LSVRRSYSSS 
    SGSLMPSLEN LDLSQVAAIS NDLKSIRTQE KAQLQDLNDR FASFIERVHE LEQQNKVLEA 
    ELLVLRQKHS EPSRFRALYE QEIRDLRLAA EDATNEKQAL QGEREGLEET LRNLQARYEE 
    EVLSREDAEG RLMEARKGAD EAALARAELE KRIDSLMDEI AFLKKVHEEE IAELQAQIQY 
    AQISVEMDVS SKPDLSAALK DIRAQYEKLA AKNMQNAEEW FKSRFTVLTE SAAKNTDAVR 
    AAKDEVSESR RLLKAKTLEI EACRGMNEAL EKQLQELEDK QNADISAMQD TINKLENELR 
    STKSEMARYL KEYQDLLNVK MALDIEIAAY RKLLEGEETR LSFTSVGSIT SGYSQSSQVF 
    GRSAYSGLQS SSYLMSARSF PAYYTSHVQE EQTEVEETIE ATKAEEAKDE PPSEGEAEEE 
    EKEKEEGEEE EGAEEEEAAK DESEDTKEEE EGGEGEEEDT KESEEEEKKE ESAGEEQVAK 
    KKD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.