Details for: Nkx2 5
Associated with
Other Information
Genular Protein ID: 3078639222
Symbol: NKX25_MOUSE
Name: Homeobox protein Nkx-2.5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7904557
Title: Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.
PubMed ID: 7904557
PubMed ID: 7910553
PubMed ID: 9778505
Title: A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice.
PubMed ID: 9778505
PubMed ID: 7690144
Title: Csx: a murine homeobox-containing gene specifically expressed in the developing heart.
PubMed ID: 7690144
PubMed ID: 9748262
Title: Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors.
PubMed ID: 9748262
PubMed ID: 9584153
Title: The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression.
PubMed ID: 9584153
PubMed ID: 12023302
Title: Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation.
PubMed ID: 12023302
DOI: 10.1101/gad.222902
PubMed ID: 14757752
Title: A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5.
PubMed ID: 14757752
PubMed ID: 15542826
Title: Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.
PubMed ID: 15542826
PubMed ID: 16556915
Title: Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field.
PubMed ID: 16556915
DOI: 10.1242/dev.02309
PubMed ID: 17584735
Title: Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.
PubMed ID: 17584735
PubMed ID: 19483677
Title: A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
PubMed ID: 19483677
DOI: 10.1038/nature08086
PubMed ID: 22560297
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
PubMed ID: 22560297
Sequence Information:
- Length: 318
- Mass: 34163
- Checksum: 6A3E7859F46D4FA6
- Sequence:
MFPSPALTPT PFSVKDILNL EQQQRSLASG DLSARLEATL APASCMLAAF KPEAYSGPEA AASGLAELRA EMGPAPSPPK CSPAFPAAPT FYPGAYGDPD PAKDPRADKK ELCALQKAVE LDKAETDGAE RPRARRRRKP RVLFSQAQVY ELERRFKQQR YLSAPERDQL ASVLKLTSTQ VKIWFQNRRY KCKRQRQDQT LELLGPPPPP ARRIAVPVLV RDGKPCLGDP AAYAPAYGVG LNAYGYNAYP YPSYGGAACS PGYSCAAYPA APPAAQPPAA SANSNFVNFG VGDLNTVQSP GMPQGNSGVS TLHGIRAW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.