Genular: Defining Cellular Identity and Function

Details for: Nmbr

Gene ID: 18101

Symbol: Nmbr

Ensembl ID: ENSMUSG00000019865

Description: neuromedin B receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Antiviral innate immune response
(GO:0140374)
Bombesin receptor activity
(GO:0004946)
Bombesin receptor signaling pathway
(GO:0031989)
Cytosol
(GO:0005829)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Membrane
(GO:0016020)
Negative regulation of interleukin-6 production
(GO:0032715)
Neuropeptide receptor activity
(GO:0008188)
Plasma membrane
(GO:0005886)
Positive regulation of interferon-alpha production
(GO:0032727)
Positive regulation of osteoclast proliferation
(GO:0090290)
Positive regulation of respiratory gaseous exchange
(GO:1903942)
Signal transduction
(GO:0007165)
Sneeze reflex
(GO:0160023)

Other Information

Proteins

Neuromedin-B receptor

Genular Protein ID: 1141641430

Symbol: NMBR_MOUSE

Name: Neuromedin-B receptor

UniProtKB Accession Codes:

O54799

Database IDs:

Citations:

PubMed ID: 9262170

Title: Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse.

PubMed ID: 9262170

DOI: 10.1016/s0006-8993(97)00380-6

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26855425

Title: The peptidergic control circuit for sighing.

PubMed ID: 26855425

DOI: 10.1038/nature16964

PubMed ID: 28780306

Title: Neuromedin B and its receptor silencing suppresses osteoclast generation by modulating precursor proliferation via M-CSF/c-Fms/D-type cyclins.

PubMed ID: 28780306

DOI: 10.1016/j.yexcr.2017.08.003

PubMed ID: 30734045

Title: Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons.

PubMed ID: 30734045

DOI: 10.2340/00015555-3143

PubMed ID: 31601264

Title: Role of neuromedin B and its receptor in the innate immune responses against influenza A virus infection in vitro and in vivo.

PubMed ID: 31601264

DOI: 10.1186/s13567-019-0695-2

PubMed ID: 34133943

Title: Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem.

PubMed ID: 34133943

DOI: 10.1016/j.cell.2021.05.017

Sequence Information:

Length: 390
Mass: 43623
Checksum: 2EA733B1DF108B42
Sequence:

MPPRSLSNLS FPTEANESEL VPEVWEKDFL PDSDGTTAEL VIRCVIPSLY LIIISVGLLG 
NIMLVKIFLT NSAMRNVPNI FISNLAAGDL LLLLTCVPVD ASRYFFDEWV FGKLGCKLIP 
AIQLTSVGVS VFTLTALSAD RYRAIVNPMD MQTSGVLLWT SLKAVGIWVV SVLLAVPEAV 
FSEVARIGSL DNSSFTACIP YPQTDELHPK IHSVLIFLVY FLIPLVIISI YYYHIAKTLI 
KSAHNLPGEY NEHTKKQMET RKRLAKIVLV FVGCFVFCWF PNHVLYLYRS FNYKEIDPSL 
GHMIVTLVAR VLSFSNSCVN PFALYLLSES FRKHFNSQLC CGRKSYPERS TSYLLSSSAV 
RMTSLKSNTK NVVTNSVLLN GHSTKQEIAL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nmbr

Associated with

Other Information

Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse. PubMed ID: 9262170

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The peptidergic control circuit for sighing. PubMed ID: 26855425

Neuromedin B and its receptor silencing suppresses osteoclast generation by modulating precursor proliferation via M-CSF/c-Fms/D-type cyclins. PubMed ID: 28780306

Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons. PubMed ID: 30734045

Role of neuromedin B and its receptor in the innate immune responses against influenza A virus infection in vitro and in vivo. PubMed ID: 31601264

Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem. PubMed ID: 34133943