Genular: Defining Cellular Identity and Function

Details for: Nme2

Gene ID: 18103

Symbol: Nme2

Ensembl ID: ENSMUSG00000020857

Description: NME/NM23 nucleoside diphosphate kinase 2

Associated with

Azathioprine adme
(R-MMU-9748787)
Drug adme
(R-MMU-9748784)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interconversion of nucleotide di- and triphosphates
(R-MMU-499943)
Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
Neutrophil degranulation
(R-MMU-6798695)
Ribavirin adme
(R-MMU-9755088)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Atp binding
(GO:0005524)
Cell periphery
(GO:0071944)
Cell projection
(GO:0042995)
Ctp biosynthetic process
(GO:0006241)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Dtmp biosynthetic process
(GO:0006231)
Enzyme binding
(GO:0019899)
Fatty acid binding
(GO:0005504)
G-quadruplex dna binding
(GO:0051880)
Gdp binding
(GO:0019003)
Gtp biosynthetic process
(GO:0006183)
Heterocyclic compound binding
(GO:1901363)
Identical protein binding
(GO:0042802)
Intermediate filament
(GO:0005882)
Intermediate filament binding
(GO:0019215)
Kinase activity
(GO:0016301)
Lamellipodium
(GO:0030027)
Metal ion binding
(GO:0046872)
Mitochondrial membrane
(GO:0031966)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Negative regulation of myeloid leukocyte differentiation
(GO:0002762)
Nucleoside diphosphate kinase activity
(GO:0004550)
Nucleotide binding
(GO:0000166)
Nucleotide metabolic process
(GO:0009117)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphorylation
(GO:0016310)
Positive regulation of neuron projection development
(GO:0010976)
Protein binding
(GO:0005515)
Protein histidine kinase activity
(GO:0004673)
Protein serine/threonine kinase activity
(GO:0004674)
Regulation of apoptotic process
(GO:0042981)
Ruffle
(GO:0001726)
Transcription coactivator activity
(GO:0003713)
Transferase activity
(GO:0016740)
Utp biosynthetic process
(GO:0006228)

Other Information

Proteins

Nucleoside diphosphate kinase B

Genular Protein ID: 222998498

Symbol: NDKB_MOUSE

Name: Nucleoside diphosphate kinase B

UniProtKB Accession Codes:

Q01768

Database IDs:

Citations:

PubMed ID: 1325378

Title: Molecular cloning and functional expression of the second mouse nm23/NDP kinase gene, nm23-M2.

PubMed ID: 1325378

DOI: 10.1016/0014-5793(92)80807-s

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16476741

Title: Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.

PubMed ID: 16476741

DOI: 10.1074/jbc.m509244200

PubMed ID: 17532299

Title: NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling.

PubMed ID: 17532299

DOI: 10.1016/j.bbrc.2007.05.090

PubMed ID: 20884616

Title: Nucleoside diphosphate kinase B knock-out mice have impaired activation of the K+ channel KCa3.1, resulting in defective T cell activation.

PubMed ID: 20884616

DOI: 10.1074/jbc.m110.168070

Sequence Information:

Length: 152
Mass: 17363
Checksum: 1A5C3F84C1FFC83C
Sequence:

MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF 
FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS 
DSVESAEKEI HLWFKPEELI DYKSCAHDWV YE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nme2

Associated with

Other Information

Molecular cloning and functional expression of the second mouse nm23/NDP kinase gene, nm23-M2. PubMed ID: 1325378

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP. PubMed ID: 16476741

NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling. PubMed ID: 17532299