Genular: Defining Cellular Identity and Function

Details for: Nqo1

Gene ID: 18104

Symbol: Nqo1

Ensembl ID: ENSMUSG00000003849

Description: NAD(P)H dehydrogenase, quinone 1

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Metabolism of polyamines
(R-MMU-351202)
Regulation of ornithine decarboxylase (odc)
(R-MMU-350562)
Cellular response to hydrogen peroxide
(GO:0070301)
Cellular response to oxidative stress
(GO:0034599)
Cytokine production
(GO:0001816)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Nad(p)h dehydrogenase (quinone) activity
(GO:0003955)
Nadh dehydrogenase (quinone) activity
(GO:0050136)
Nadh oxidation
(GO:0006116)
Nadph oxidation
(GO:0070995)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of catalytic activity
(GO:0043086)
Negative regulation of protein catabolic process
(GO:0042177)
Neuronal cell body
(GO:0043025)
Nucleus
(GO:0005634)
Oxidoreductase activity
(GO:0016491)
Positive regulation of neuron apoptotic process
(GO:0043525)
Protein binding
(GO:0005515)
Protein catabolic process
(GO:0030163)
Protein polyubiquitination
(GO:0000209)
Removal of superoxide radicals
(GO:0019430)
Response to amine
(GO:0014075)
Response to l-glutamine
(GO:1904844)
Response to lipopolysaccharide
(GO:0032496)
Response to oxidative stress
(GO:0006979)
Response to xenobiotic stimulus
(GO:0009410)
Superoxide dismutase activity
(GO:0004784)
Superoxide metabolic process
(GO:0006801)
Ubiquinone metabolic process
(GO:0006743)
Vitamin e metabolic process
(GO:0042360)
Vitamin k metabolic process
(GO:0042373)

Other Information

Proteins

NAD(P)H dehydrogenase [quinone] 1

Genular Protein ID: 2542189458

Symbol: NQO1_MOUSE

Name: NAD(P)H dehydrogenase [quinone] 1

UniProtKB Accession Codes:

Q64669

Database IDs:

Citations:

PubMed ID: 7704040

Title: Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels.

PubMed ID: 7704040

PubMed ID: 7527260

Title: Mouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis.

PubMed ID: 7527260

DOI: 10.1002/pro.5560030816

PubMed ID: 8999809

Title: Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse.

PubMed ID: 8999809

DOI: 10.1074/jbc.272.3.1437

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 10706635

Title: Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release.

PubMed ID: 10706635

DOI: 10.1073/pnas.97.7.3177

Sequence Information:

Length: 274
Mass: 30960
Checksum: 68F380922FD72965
Sequence:

MAARRALIVL AHSEKTSFNY AMKEAAVEAL KKRGWEVLES DLYAMNFNPI ISRNDITGEL 
KDSKNFQYPS ESSLAYKEGR LSPDIVAEHK KLEAADLVIF QFPLQWFGVP AILKGWFERV 
LVAGFAYTYA AMYDNGPFQN KKTLLSITTG GSGSMYSLQG VHGDMNVILW PIQSGILRFC 
GFQVLEPQLV YSIGHTPPDA RMQILEGWKK RLETVWEETP LYFAPSSLFD LNFQAGFLMK 
KEVQEEQKKN KFGLSVGHHL GKSIPADNQI KARK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nqo1

Associated with

Other Information

Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels. PubMed ID: 7704040

Mouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis. PubMed ID: 7527260

Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse. PubMed ID: 8999809