Genular: Defining Cellular Identity and Function

Details for: Nog

Gene ID: 18121

Symbol: Nog

Ensembl ID: ENSMUSG00000048616

Description: noggin

Associated with

Signaling by bmp
(R-MMU-201451)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Anatomical structure formation involved in morphogenesis
(GO:0048646)
Atrial cardiac muscle tissue morphogenesis
(GO:0055009)
Axial mesoderm development
(GO:0048318)
Axon guidance
(GO:0007411)
Bmp signaling pathway
(GO:0030509)
Brain development
(GO:0007420)
Cartilage development
(GO:0051216)
Cell differentiation
(GO:0030154)
Cell differentiation in hindbrain
(GO:0021533)
Cell population proliferation
(GO:0008283)
Cellular response to bmp stimulus
(GO:0071773)
Central nervous system development
(GO:0007417)
Cytokine binding
(GO:0019955)
Dorsal/ventral pattern formation
(GO:0009953)
Embryonic digit morphogenesis
(GO:0042733)
Embryonic skeletal joint morphogenesis
(GO:0060272)
Embryonic skeletal system development
(GO:0048706)
Endocardial cushion formation
(GO:0003272)
Endoderm development
(GO:0007492)
Endoderm formation
(GO:0001706)
Epithelial cell proliferation
(GO:0050673)
Epithelial to mesenchymal transition
(GO:0001837)
Exploration behavior
(GO:0035640)
Face morphogenesis
(GO:0060325)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Forebrain development
(GO:0030900)
Heart trabecula morphogenesis
(GO:0061384)
In utero embryonic development
(GO:0001701)
Limb development
(GO:0060173)
Long-term synaptic potentiation
(GO:0060291)
Lung morphogenesis
(GO:0060425)
Membranous septum morphogenesis
(GO:0003149)
Memory
(GO:0007613)
Mesenchymal cell differentiation
(GO:0048762)
Mesoderm formation
(GO:0001707)
Middle ear morphogenesis
(GO:0042474)
Motor neuron axon guidance
(GO:0008045)
Multicellular organism development
(GO:0007275)
Negative regulation of astrocyte differentiation
(GO:0048712)
Negative regulation of bmp signaling pathway
(GO:0030514)
Negative regulation of cardiac epithelial to mesenchymal transition
(GO:0062044)
Negative regulation of cardiac muscle cell proliferation
(GO:0060044)
Negative regulation of cartilage development
(GO:0061037)
Negative regulation of cell differentiation
(GO:0045596)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of cytokine activity
(GO:0060302)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of osteoblast differentiation
(GO:0045668)
Negative regulation of smad protein signal transduction
(GO:0060392)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural plate anterior/posterior regionalization
(GO:0021999)
Neural plate morphogenesis
(GO:0001839)
Neural tube closure
(GO:0001843)
Neural tube development
(GO:0021915)
Nodal signaling pathway
(GO:0038092)
Notochord morphogenesis
(GO:0048570)
Osteoblast differentiation
(GO:0001649)
Outflow tract morphogenesis
(GO:0003151)
Pattern specification process
(GO:0007389)
Pharyngeal arch artery morphogenesis
(GO:0061626)
Pituitary gland development
(GO:0021983)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of oligodendrocyte progenitor proliferation
(GO:0070447)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Prostatic bud formation
(GO:0060513)
Protein-containing complex binding
(GO:0044877)
Protein homodimerization activity
(GO:0042803)
Regulation of bmp signaling pathway
(GO:0030510)
Regulation of fibroblast growth factor receptor signaling pathway
(GO:0040036)
Regulation of neuronal synaptic plasticity
(GO:0048168)
Skeletal system development
(GO:0001501)
Smoothened signaling pathway
(GO:0007224)
Somatic stem cell population maintenance
(GO:0035019)
Somite development
(GO:0061053)
Specification of segmental identity, mandibular segment
(GO:0042305)
Spinal cord development
(GO:0021510)
Stem cell differentiation
(GO:0048863)
Ureteric bud development
(GO:0001657)
Ureteric bud formation
(GO:0060676)
Urogenital system development
(GO:0001655)
Ventricular compact myocardium morphogenesis
(GO:0003223)
Ventricular septum morphogenesis
(GO:0060412)
Visual learning
(GO:0008542)
Wound healing
(GO:0042060)

Other Information

Proteins

NOGG_MOUSE

Genular Protein ID: 1285172257

Symbol: NOGG_MOUSE

Name: N/A

UniProtKB Accession Codes:

P97466

Database IDs:

Citations:

PubMed ID: 9585504

Title: Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite.

PubMed ID: 9585504

DOI: 10.1101/gad.12.10.1438

PubMed ID: 9603738

Title: Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton.

PubMed ID: 9603738

DOI: 10.1126/science.280.5368.1455

Sequence Information:

Length: 232
Mass: 25770
Checksum: 0192AF6373B78B74
Sequence:

MERCPSLGVT LYALVVVLGL RAAPAGGQHY LHIRPAPSDN LPLVDLIEHP DPIFDPKEKD 
LNETLLRSLL GGHYDPGFMA TSPPEDRPGG GGGPAGGAED LAELDQLLRQ RPSGAMPSEI 
KGLEFSEGLA QGKKQRLSKK LRRKLQMWLW SQTFCPVLYA WNDLGSRFWP RYVKVGSCFS 
KRSCSVPEGM VCKPSKSVHL TVLRWRCQRR GGQRCGWIPI QYPIISECKC SC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.