Details for: Nos2
Associated with
Other Information
Genular Protein ID: 2185657001
Symbol: NOS2_MOUSE
Name: Nitric oxide synthase, inducible
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1373522
Title: Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.
PubMed ID: 1373522
PubMed ID: 1379716
Title: Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.
PubMed ID: 1379716
PubMed ID: 1372907
Title: Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.
PubMed ID: 1372907
PubMed ID: 7503239
Title: Role of NF-kappa B in the regulation of inducible nitric oxide synthase in an MTAL cell line.
PubMed ID: 7503239
PubMed ID: 10438970
Title: Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.
PubMed ID: 10438970
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7544010
Title: The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
PubMed ID: 7544010
PubMed ID: 16373578
Title: Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2.
PubMed ID: 16373578
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 20603330
Title: The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.
PubMed ID: 20603330
PubMed ID: 21199876
Title: Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins.
PubMed ID: 21199876
PubMed ID: 22081021
Title: Requirement of argininosuccinate lyase for systemic nitric oxide production.
PubMed ID: 22081021
DOI: 10.1038/nm.2544
PubMed ID: 22073225
Title: The circadian deadenylase Nocturnin is necessary for stabilization of the iNOS mRNA in mice.
PubMed ID: 22073225
PubMed ID: 9334294
Title: The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
PubMed ID: 9334294
PubMed ID: 9516116
Title: Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.
PubMed ID: 9516116
PubMed ID: 10562538
Title: Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction.
PubMed ID: 10562538
PubMed ID: 10562539
Title: N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.
PubMed ID: 10562539
PubMed ID: 10769116
Title: Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins.
PubMed ID: 10769116
DOI: 10.1021/bi992409a
PubMed ID: 11669619
Title: Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.
PubMed ID: 11669619
DOI: 10.1021/bi011183k
PubMed ID: 12437348
Title: Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.
PubMed ID: 12437348
DOI: 10.1021/bi026313j
PubMed ID: 12464241
Title: Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase -- structural models of the short-lived oxygen complexes.
PubMed ID: 12464241
Sequence Information:
- Length: 1144
- Mass: 130575
- Checksum: 0735BE676113457F
- Sequence:
MACPWKFLFK VKSYQSDLKE EKDINNNVKK TPCAVLSPTI QDDPKSHQNG SPQLLTGTAQ NVPESLDKLH VTSTRPQYVR IKNWGSGEIL HDTLHHKATS DFTCKSKSCL GSIMNPKSLT RGPRDKPTPL EELLPHAIEF INQYYGSFKE AKIEEHLARL EAVTKEIETT GTYQLTLDEL IFATKMAWRN APRCIGRIQW SNLQVFDARN CSTAQEMFQH ICRHILYATN NGNIRSAITV FPQRSDGKHD FRLWNSQLIR YAGYQMPDGT IRGDAATLEF TQLCIDLGWK PRYGRFDVLP LVLQADGQDP EVFEIPPDLV LEVTMEHPKY EWFQELGLKW YALPAVANML LEVGGLEFPA CPFNGWYMGT EIGVRDFCDT QRYNILEEVG RRMGLETHTL ASLWKDRAVT EINVAVLHSF QKQNVTIMDH HTASESFMKH MQNEYRARGG CPADWIWLVP PVSGSITPVF HQEMLNYVLS PFYYYQIEPW KTHIWQNEKL RPRRREIRFR VLVKVVFFAS MLMRKVMASR VRATVLFATE TGKSEALARD LATLFSYAFN TKVVCMDQYK ASTLEEEQLL LVVTSTFGNG DCPSNGQTLK KSLFMLRELN HTFRYAVFGL GSSMYPQFCA FAHDIDQKLS HLGASQLAPT GEGDELSGQE DAFRSWAVQT FRAACETFDV RSKHHIQIPK RFTSNATWEP QQYRLIQSPE PLDLNRALSS IHAKNVFTMR LKSQQNLQSE KSSRTTLLVQ LTFEGSRGPS YLPGEHLGIF PGNQTALVQG ILERVVDCPT PHQTVCLEVL DESGSYWVKD KRLPPCSLSQ ALTYFLDITT PPTQLQLHKL ARFATDETDR QRLEALCQPS EYNDWKFSNN PTFLEVLEEF PSLHVPAAFL LSQLPILKPR YYSISSSQDH TPSEVHLTVA VVTYRTRDGQ GPLHHGVCST WIRNLKPQDP VPCFVRSVSG FQLPEDPSQP CILIGPGTGI APFRSFWQQR LHDSQHKGLK GGRMSLVFGC RHPEEDHLYQ EEMQEMVRKR VLFQVHTGYS RLPGKPKVYV QDILQKQLAN EVLSVLHGEQ GHLYICGDVR MARDVATTLK KLVATKLNLS EEQVEDYFFQ LKSQKRYHED IFGAVFSYGA KKGSALEEPK ATRL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.