Genular: Defining Cellular Identity and Function

Details for: Nup50

Gene ID: 18141

Symbol: Nup50

Ensembl ID: ENSMUSG00000016619

Description: nucleoporin 50

Associated with

Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to heat stress
(R-MMU-3371556)
Gene expression (transcription)
(R-MMU-74160)
Gene silencing by rna
(R-MMU-211000)
Glucose metabolism
(R-MMU-70326)
Glycolysis
(R-MMU-70171)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of non-coding rna
(R-MMU-194441)
Metabolism of proteins
(R-MMU-392499)
Metabolism of rna
(R-MMU-8953854)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Nuclear envelope breakdown
(R-MMU-2980766)
Nuclear pore complex (npc) disassembly
(R-MMU-3301854)
Post-translational protein modification
(R-MMU-597592)
Processing of capped intron-containing pre-mrna
(R-MMU-72203)
Regulation of glucokinase by glucokinase regulatory protein
(R-MMU-170822)
Regulation of hsf1-mediated heat shock response
(R-MMU-3371453)
Snrnp assembly
(R-MMU-191859)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of chromatin organization proteins
(R-MMU-4551638)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Sumoylation of dna replication proteins
(R-MMU-4615885)
Sumoylation of rna binding proteins
(R-MMU-4570464)
Sumoylation of sumoylation proteins
(R-MMU-4085377)
Sumoylation of ubiquitinylation proteins
(R-MMU-3232142)
Transcriptional regulation by small rnas
(R-MMU-5578749)
Transport of mature mrna derived from an intron-containing transcript
(R-MMU-159236)
Transport of mature mrna derived from an intronless transcript
(R-MMU-159231)
Transport of mature mrnas derived from intronless transcripts
(R-MMU-159234)
Transport of mature transcript to cytoplasm
(R-MMU-72202)
Transport of the slbp dependant mature mrna
(R-MMU-159230)
Transport of the slbp independent mature mrna
(R-MMU-159227)
Neural tube formation
(GO:0001841)
Nuclear envelope
(GO:0005635)
Nuclear membrane
(GO:0031965)
Nuclear pore
(GO:0005643)
Nucleocytoplasmic transport
(GO:0006913)
Nucleoplasm
(GO:0005654)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Ribonucleoprotein complex
(GO:1990904)

Other Information

Proteins

Nuclear pore complex protein Nup50

Genular Protein ID: 13150714

Symbol: NUP50_MOUSE

Name: Nuclear pore complex protein Nup50

UniProtKB Accession Codes:

Q9JIH2 Q3TG43 Q3TN17 Q6P1F4 Q6PAL4 Q8C2Y6 Q9CU02 Q9JK85

Database IDs:

Citations:

PubMed ID: 10891500

Title: Characterization and targeted disruption of murine nup50, a p27(Kip1)-interacting component of the nuclear pore complex.

PubMed ID: 10891500

DOI: 10.1128/mcb.20.15.5631-5642.2000

PubMed ID: 10811608

Title: Cyclin E-mediated elimination of p27 requires its interaction with the nuclear pore-associated protein mNPAP60.

PubMed ID: 10811608

DOI: 10.1093/emboj/19.10.2168

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 16222336

Title: Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling.

PubMed ID: 16222336

DOI: 10.1038/sj.emboj.7600843

Sequence Information:

Length: 466
Mass: 49485
Checksum: 8B9216CBB613661A
Sequence:

MAKRVAEKEL TDRNWDEEDE VEEMGTFSVA SEEVMKNRAV KKAKRRNVGF ESDSGGAFKG 
FKGLVVPSGG GGFSGFGGSG GKPLEGLTNG NSTDNATPFS NVKTAAEPKA AFGSFAVNGP 
TTLVDKKISS PKCNNSNQPP SSGPASSTAC PGNAYHKQLA GLNCSVRDWI VKHVNTNPLC 
DLTPIFKDYE RYLATIEKQL ENGGGSSSES QTDRATAGME PPSLFGSTKL QQESPFSFHG 
NKAEDTSEKV EFTAEKKSDA AQGATSASFS FGKKIESSAL GSLSSGSLTG FSFSAGSSSL 
FGKDAAQSKA ASSLFSAKAS ESPAGGGSSE CRDGEEEEND EPPKVVVTEV KEEDAFYSKK 
CKLFYKKDNE FKEKGVGTLH LKPTATQKTQ LLVRADTNLG NILLNVLIAP NMPCTRTGKN 
NVLIVCVPNP PLDEKQPTLP ATMLIRVKTS EDADELHKIL LEKKDA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nup50

Associated with

Other Information

Characterization and targeted disruption of murine nup50, a p27(Kip1)-interacting component of the nuclear pore complex. PubMed ID: 10891500

Cyclin E-mediated elimination of p27 requires its interaction with the nuclear pore-associated protein mNPAP60. PubMed ID: 10811608

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling. PubMed ID: 16222336