Details for: Slc11a2

Gene ID: 18174

Symbol: Slc11a2

Ensembl ID: ENSMUSG00000023030

Description: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Associated with

Other Information

Genular Protein ID: 4131498215

Symbol: NRAM2_MOUSE

Name: Natural resistance-associated macrophage protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7789986

Title: Identification and characterization of a second mouse Nramp gene.

PubMed ID: 7789986

DOI: 10.1016/0888-7543(95)80053-o

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12209011

Title: Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function.

PubMed ID: 12209011

DOI: 10.1073/pnas.192423399

PubMed ID: 10361139

Title: Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.

PubMed ID: 10361139

PubMed ID: 11739192

Title: Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.

PubMed ID: 11739192

DOI: 10.1182/blood.v98.13.3823

PubMed ID: 15849611

Title: Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver.

PubMed ID: 15849611

DOI: 10.1172/jci24356

PubMed ID: 16475818

Title: Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2).

PubMed ID: 16475818

DOI: 10.1021/bi052307m

PubMed ID: 17293870

Title: Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

PubMed ID: 17293870

DOI: 10.1038/nm1542

PubMed ID: 18776082

Title: Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

PubMed ID: 18776082

DOI: 10.1182/blood-2008-04-150953

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27462458

Title: Regulation of the divalent metal ion transporter via membrane budding.

PubMed ID: 27462458

DOI: 10.1038/celldisc.2016.11

PubMed ID: 9241278

Title: Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene.

PubMed ID: 9241278

DOI: 10.1038/ng0897-383

Sequence Information:

  • Length: 568
  • Mass: 62368
  • Checksum: 603AAF697AAD3C74
  • Sequence:
  • MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
    EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
    LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
    PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYITVK PSQSQVLRGM 
    FVPSCPGCRT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
    CIALFVSFII NVFVVSVFAE AFFEKTNKQV VEVCKNNSSP HADLFPSDNS TLAVDIYKGG 
    VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
    IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
    GILVLIVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLT FVFYLGWQCL IALGLSFLDC 
    GRSYRLGLTA QPELYLLNTV DADSVVSR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.