Genular: Defining Cellular Identity and Function

Details for: Nsf

Gene ID: 18195

Symbol: Nsf

Ensembl ID: ENSMUSG00000034187

Description: N-ethylmaleimide sensitive fusion protein

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Copi-dependent golgi-to-er retrograde traffic
(R-MMU-6811434)
Copi-mediated anterograde transport
(R-MMU-6807878)
Copii-mediated vesicle transport
(R-MMU-204005)
Er to golgi anterograde transport
(R-MMU-199977)
Glutamate binding, activation of ampa receptors and synaptic plasticity
(R-MMU-399721)
Golgi-to-er retrograde transport
(R-MMU-8856688)
Intra-golgi and retrograde golgi-to-er traffic
(R-MMU-6811442)
Intra-golgi traffic
(R-MMU-6811438)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Post-translational protein modification
(R-MMU-597592)
Retrograde transport at the trans-golgi-network
(R-MMU-6811440)
Trafficking of ampa receptors
(R-MMU-399719)
Trafficking of glur2-containing ampa receptors
(R-MMU-416993)
Transmission across chemical synapses
(R-MMU-112315)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Atp-dependent protein binding
(GO:0043008)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
D1 dopamine receptor binding
(GO:0031748)
Dendritic shaft
(GO:0043198)
Golgi apparatus
(GO:0005794)
Golgi stack
(GO:0005795)
Golgi to plasma membrane protein transport
(GO:0043001)
Hydrolase activity
(GO:0016787)
Intra-golgi vesicle-mediated transport
(GO:0006891)
Intracellular protein transport
(GO:0006886)
Ionotropic glutamate receptor binding
(GO:0035255)
Metal ion binding
(GO:0046872)
Myelin sheath
(GO:0043209)
Nucleotide binding
(GO:0000166)
Pdz domain binding
(GO:0030165)
Plasma membrane
(GO:0005886)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of receptor-mediated endocytosis
(GO:0048260)
Positive regulation of receptor recycling
(GO:0001921)
Potassium ion transport
(GO:0006813)
Protein-containing complex binding
(GO:0044877)
Protein-containing complex disassembly
(GO:0032984)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein serine/threonine kinase binding
(GO:0120283)
Protein transport
(GO:0015031)
Regulation of exocytosis
(GO:0017157)
Regulation of receptor internalization
(GO:0002090)
Small gtpase binding
(GO:0031267)
Snare complex disassembly
(GO:0035494)
Syntaxin-1 binding
(GO:0017075)
Syntaxin binding
(GO:0019905)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

Vesicle-fusing ATPase

Genular Protein ID: 1926333328

Symbol: NSF_MOUSE

Name: Vesicle-fusing ATPase

UniProtKB Accession Codes:

P46460 A2A646 Q8BQ65 Q8C3R2 Q8CCT9 Q8CEF0 Q923C6

Database IDs:

Citations:

PubMed ID: 8082782

Title: Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast.

PubMed ID: 8082782

DOI: 10.1016/0014-5793(94)00879-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16461345

Title: Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis.

PubMed ID: 16461345

DOI: 10.1074/jbc.m513496200

PubMed ID: 18272689

Title: Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin.

PubMed ID: 18272689

DOI: 10.1523/jneurosci.4130-07.2008

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 744
Mass: 82613
Checksum: BE55AD0056AD5585
Sequence:

MAGRTMQAAR CPTDELSLSN CAVVNEKDFQ SGQHVMVRTS PNHKYIFTLR THPSVVPGCI 
AFSLPQRKWA GLSIGQDIEV ALYSFDKAKQ CIGTMTIEID FLQKKNIDSN PYDTDKMAAE 
FIQQFNNQAF SVGQQLVFSF NDKLFGLLVK DIEAMDPSIL KGEPASGKRQ KIEVGLVVGN 
SQVAFEKAEN SSLNLIGKAK TKENRQSIIN PDWNFEKMGI GGLDKEFSDI FRRAFASRVF 
PPEIVEQMGC KHVKGILLYG PPGCGKTLLA RQIGKMLNAR EPKVVNGPEI LNKYVGESEA 
NIRKLFADAE EEQRRLGANS GLHIIIFDEI DAICKQRGSM AGSTGVHDTV VNQLLSKIDG 
VEQLNNILVI GMTNRPDLID EALLRPGRLE VKMEIGLPDE KGRLQILHIH TARMRGHQLL 
SADVDIKELA VETKNFSGAE LEGLVRAAQS TAMNRHIKAS TKVEVDMEKA ESLQVTRGDF 
LASLENDIKP AFGTNQEDYA SYIMNGIIKW GDPVTRVLDD GELLVQQTKN SDRTPLVSVL 
LEGPPHSGKT ALAAKIAEES NFPFIKICSP DKMIGFSETA KCQAMKKIFD DAYKSQLSCV 
VVDDIERLLD YVPIGPRFSN LVLQALLVLL KKAPPQGRKL LIIGTTSRKD VLQEMEMLNA 
FSTTIHVPNI ATGEQLLEAL ELLGNFKDKE RTTIAQQVKG KKVWIGIKKL LMLIEMSLQM 
DPEYRVRKFL ALMREEGASP LDFD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nsf

Associated with

Other Information

Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. PubMed ID: 8082782

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. PubMed ID: 16461345

Muscle-specific receptor tyrosine kinase endocytosis in acetylcholine receptor clustering in response to agrin. PubMed ID: 18272689

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337