Genular: Defining Cellular Identity and Function

Details for: Nsg1

Gene ID: 18196

Symbol: Nsg1

Ensembl ID: ENSMUSG00000029126

Description: neuron specific gene family member 1

Associated with

Amyloid precursor protein metabolic process
(GO:0042982)
Apoptotic process
(GO:0006915)
Cell projection
(GO:0042995)
Clathrin coat assembly
(GO:0048268)
Clathrin light chain binding
(GO:0032051)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Dopamine receptor signaling pathway
(GO:0007212)
Early endosome
(GO:0005769)
Early endosome membrane
(GO:0031901)
Endoplasmic reticulum
(GO:0005783)
Endosomal transport
(GO:0016197)
Endosome
(GO:0005768)
Glutamatergic synapse
(GO:0098978)
Golgi apparatus
(GO:0005794)
Ionotropic glutamate receptor binding
(GO:0035255)
Late endosome
(GO:0005770)
Lateral plasma membrane
(GO:0016328)
Lysosomal lumen
(GO:0043202)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Neurotransmitter receptor cycle
(GO:0099627)
Neurotransmitter receptor transport, endosome to postsynaptic membrane
(GO:0098887)
Positive regulation of receptor recycling
(GO:0001921)
Postsynaptic endosome
(GO:0098845)
Postsynaptic membrane
(GO:0045211)
Postsynaptic neurotransmitter receptor cycle
(GO:0099630)
Protein binding
(GO:0005515)
Receptor recycling
(GO:0001881)
Recycling endosome membrane
(GO:0055038)
Regulation of long-term synaptic potentiation
(GO:1900271)
Signaling receptor binding
(GO:0005102)
Somatodendritic compartment
(GO:0036477)
Spontaneous synaptic transmission
(GO:0098814)
Trans-golgi network membrane
(GO:0032588)
Vesicle-mediated transport in synapse
(GO:0099003)

Other Information

Proteins

M234

Genular Protein ID: 4211278633

Symbol: NSG1_MOUSE

Name: M234

UniProtKB Accession Codes:

Q62092 O54717 Q3UF63 Q922E5

Database IDs:

Citations:

PubMed ID: 9013775

Title: Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons.

PubMed ID: 9013775

DOI: 10.1016/s0169-328x(96)00115-5

PubMed ID: 9461575

Title: A 21-kDa polypeptide belonging to a new family of proteins is expressed in the Golgi apparatus of neural and germ cells.

PubMed ID: 9461575

DOI: 10.1074/jbc.273.7.3909

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12070131

Title: Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD.

PubMed ID: 12070131

DOI: 10.1083/jcb.200202022

PubMed ID: 15187090

Title: Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors.

PubMed ID: 15187090

DOI: 10.1074/jbc.m402751200

PubMed ID: 16037816

Title: Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2.

PubMed ID: 16037816

DOI: 10.1038/sj.emboj.7600755

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21084623

Title: Identification of NEEP21 as a ss-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro.

PubMed ID: 21084623

DOI: 10.1523/jneurosci.4464-10.2010

PubMed ID: 28299779

Title: The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo.

PubMed ID: 28299779

DOI: 10.1002/cne.24168

PubMed ID: 28874679

Title: The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes.

PubMed ID: 28874679

DOI: 10.1038/s41598-017-07667-x

Sequence Information:

Length: 185
Mass: 20929
Checksum: B184238A71710C1F
Sequence:

MVKLGNNFAE KGTKQPLLED GFDTIPLMTP LDVNQLQFPP PDKVVVKTKT EYEPDRKKGK 
ARPPKIAEFT VSITEGVTER FKVSVLVLFA LAFLTCVVFL VVYKVYKYDR ACPDGFVLKN 
TQCIPEGLES YYTEQDSSAR EKFYTVINHY NVAKQSITRS VSPWMSVLSE EKLSEQETEA 
AEKSA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nsg1

Associated with

Other Information

Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons. PubMed ID: 9013775

A 21-kDa polypeptide belonging to a new family of proteins is expressed in the Golgi apparatus of neural and germ cells. PubMed ID: 9461575

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD. PubMed ID: 12070131

Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors. PubMed ID: 15187090

Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. PubMed ID: 16037816

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Identification of NEEP21 as a ss-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro. PubMed ID: 21084623

The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. PubMed ID: 28299779

The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. PubMed ID: 28874679