Details for: Nxn

Gene ID: 18230

Symbol: Nxn

Ensembl ID: ENSMUSG00000020844

Description: nucleoredoxin

Associated with

Other Information

Genular Protein ID: 3786595390

Symbol: NXN_MOUSE

Name: Nucleoredoxin

UniProtKB Accession Codes:

P97346 Q5H8T6 Q5H8U0 Q99KF3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EC 3 EMBL 14 EPD 1 Ensembl 1 GO 10 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 1 Rhea 6 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9119370

Title: Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin.

PubMed ID: 9119370

DOI: 10.1006/geno.1996.4493

PubMed ID: 15670764

Title: Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11.

PubMed ID: 15670764

DOI: 10.1016/j.bbrc.2004.12.149

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10903915

Title: Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells.

PubMed ID: 10903915

DOI: 10.1006/bbrc.2000.3106

PubMed ID: 16764867

Title: Interaction of nucleoredoxin with protein phosphatase 2A.

PubMed ID: 16764867

DOI: 10.1016/j.febslet.2006.04.101

PubMed ID: 16604061

Title: The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled.

PubMed ID: 16604061

DOI: 10.1038/ncb1405

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20970343

Title: Nucleoredoxin sustains Wnt/beta-catenin signaling by retaining a pool of inactive dishevelled protein.

PubMed ID: 20970343

DOI: 10.1016/j.cub.2010.09.065

Sequence Information:

  • Length: 435
  • Mass: 48344
  • Checksum: C2AE7A65A5AB7843
  • Sequence:
    • MSGFLEELLG DKLVTGGGEE VDVHSLGARG IALLGLYFGC SLSAPCAQLS ASLAAFYGRL 
RGDAAAGPGA GAGAGAAAEP EPRHRLEIVF VSSDQDQRQW QDFVRDMPWL ALPYKEKHRK 
LKLWNKYRVS NIPSLIFLDA TTGKVVCRNG LLVIRDDPEG LEFPWGPKPF REVIAGPLLR 
NNGQSLESSS LEGSHVGVYF SAHWCPPCRS LTRVLVESYR KIKEAGQEFE IIFVSADRSE 
ESFKQYFSEM PWLAVPYTDE ARRSRLNRLY GIQGIPTLIV LDPQGEVITR QGRVEVLNDE 
DCREFPWHPK PVLELSDSNA VQLNEGPCLV LFVDSEDDGE SEAAKQLIQP IAEKIIAKYK 
AKEEEAPLLF FVAGEDDMTD SLRDYTNLPE AAPLLTILDM SARAKYVMDV EEITPAIVET 
FVNDFLAEKL KPEPI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.