Genular: Defining Cellular Identity and Function

Details for: Gpr143

Gene ID: 18241

Symbol: Gpr143

Ensembl ID: ENSMUSG00000025333

Description: G protein-coupled receptor 143

Associated with

Amine ligand-binding receptors
(R-MMU-375280)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Signaling by gpcr
(R-MMU-372790)
Apical plasma membrane
(GO:0016324)
Calcium-mediated signaling using intracellular calcium source
(GO:0035584)
Dopamine binding
(GO:0035240)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
L-dopa binding
(GO:0072544)
L-dopa receptor activity
(GO:0035643)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Melanosome
(GO:0042470)
Melanosome localization
(GO:0032400)
Melanosome membrane
(GO:0033162)
Melanosome organization
(GO:0032438)
Melanosome transport
(GO:0032402)
Membrane
(GO:0016020)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Regulation of calcium-mediated signaling
(GO:0050848)
Regulation of melanosome organization
(GO:1903056)
Regulation of melanosome transport
(GO:1902908)
Signal transduction
(GO:0007165)
Tyrosine binding
(GO:0072545)

Other Information

Proteins

G-protein coupled receptor 143

Genular Protein ID: 2260035709

Symbol: GP143_MOUSE

Name: G-protein coupled receptor 143

UniProtKB Accession Codes:

P70259 O89031

Database IDs:

Citations:

PubMed ID: 8889556

Title: Cloning of the murine homolog of the ocular albinism type 1 (OA1) gene: sequence, genomic structure, and expression analysis in pigment cells.

PubMed ID: 8889556

DOI: 10.1101/gr.6.9.880

PubMed ID: 8921399

Title: Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene.

PubMed ID: 8921399

DOI: 10.1006/geno.1996.0545

PubMed ID: 18697795

Title: The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells.

PubMed ID: 18697795

DOI: 10.1093/hmg/ddn241

Sequence Information:

Length: 405
Mass: 44564
Checksum: 716405A6512ED312
Sequence:

MASPRLGIFC CPTWDAATQL VLSFQPRVFH ALCLGSGTLR LVLGLLQLLS GRRSVGHRAP 
ATSPAASVHI LRAATACDLL GCLGIVIRST VWIAYPEFIE NISNVNATDI WPATFCVGSA 
MWIQLLYSAC FWWLFCYAVD VYLVIRRSAG RSTILLYHIM AWGLAVLLCV EGAVMLYYPS 
VSRCERGLDH AIPHYVTTYL PLLLVLVANP ILFHKTVTSV ASLLKGRKGV YTENERLMGA 
VIKTRFFKIM LVLIACWLSN IINESLLFYL EMQPDIHGGS LKRIQNAART TWFIMGILNP 
AQGLLLSLAF YGWTGCSLDV HPPKMVIQWE TMTASAAEGT YQTPVRSCVP HQNPRKVVCV 
GGHTSDEVLS ILSEDSDAST VEIHTATGSC NIKEVDSISQ AQGEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.