Genular: Defining Cellular Identity and Function

Details for: Oaz1

Gene ID: 18245

Symbol: Oaz1

Ensembl ID: ENSMUSG00000035242

Description: ornithine decarboxylase antizyme 1

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Metabolism of polyamines
(R-MMU-351202)
Regulation of ornithine decarboxylase (odc)
(R-MMU-350562)
Cellular response to leptomycin b
(GO:0072750)
Cellular response to polyamine macromolecule
(GO:1904584)
Cytoplasm
(GO:0005737)
Enzyme binding
(GO:0019899)
Negative regulation of ornithine catabolic process
(GO:1903267)
Negative regulation of polyamine transmembrane transport
(GO:1902268)
Nucleus
(GO:0005634)
Ornithine decarboxylase inhibitor activity
(GO:0008073)
Polyamine biosynthetic process
(GO:0006596)
Polyamine metabolic process
(GO:0006595)
Positive regulation of intracellular protein transport
(GO:0090316)
Positive regulation of proteasomal protein catabolic process
(GO:1901800)
Positive regulation of protein catabolic process
(GO:0045732)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)

Other Information

Proteins

Ornithine decarboxylase antizyme 1

Genular Protein ID: 4181037732

Symbol: OAZ1_MOUSE

Name: Ornithine decarboxylase antizyme 1

UniProtKB Accession Codes:

P54369 O08610

Database IDs:

Citations:

PubMed ID: 9428668

Title: Polyamines regulate both transcription and translation of the gene encoding ornithine decarboxylase antizyme in mouse.

PubMed ID: 9428668

DOI: 10.1111/j.1432-1033.1997.0223a.x

PubMed ID: 16916800

Title: Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity.

PubMed ID: 16916800

DOI: 10.1074/jbc.m602840200

PubMed ID: 18062773

Title: ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1.

PubMed ID: 18062773

DOI: 10.1042/bj20071423

PubMed ID: 18508777

Title: Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells.

PubMed ID: 18508777

DOI: 10.1074/jbc.m801024200

PubMed ID: 19449338

Title: Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes.

PubMed ID: 19449338

DOI: 10.1002/jcb.22168

PubMed ID: 24967154

Title: Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.

PubMed ID: 24967154

DOI: 10.1016/j.fob.2014.05.004

Sequence Information:

Length: 227
Mass: 25133
Checksum: C2D0E1614C5F28A5
Sequence:

MVKSSLQRIL NSHCFAREKE GDKRSATLHA SRTMPLLSQH SRGGCSSESS RVALNCCSNL 
GPGPRWCSDV PHPPLKIPGG RGNSQRDHSL SASILYSDER LNVTEEPTSN DKTRVLSIQS 
TLTEAKQVTW RAVWSGGGLY IELPAGPLPE GSKDSFAALL EFAEEQLQAD HVFICFPKNR 
EDRAALLRTF SFLGFEIVRP GHPLVPKRPD ACFMVYTLER EDPGEED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Oaz1

Associated with

Other Information

Polyamines regulate both transcription and translation of the gene encoding ornithine decarboxylase antizyme in mouse. PubMed ID: 9428668

Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity. PubMed ID: 16916800

ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1. PubMed ID: 18062773

Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells. PubMed ID: 18508777

Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes. PubMed ID: 19449338