Genular: Defining Cellular Identity and Function

Details for: Nobox

Gene ID: 18291

Symbol: Nobox

Ensembl ID: ENSMUSG00000029736

Description: NOBOX oogenesis homeobox

Associated with

Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Multicellular organism development
(GO:0007275)
Nucleus
(GO:0005634)
Oogenesis
(GO:0048477)
Ovarian follicle development
(GO:0001541)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Transcription by rna polymerase ii
(GO:0006366)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Homeobox protein NOBOX

Genular Protein ID: 4286245047

Symbol: NOBOX_MOUSE

Name: Homeobox protein NOBOX

UniProtKB Accession Codes:

Q8VIH1 P70367

Database IDs:

Citations:

PubMed ID: 11804785

Title: Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes.

PubMed ID: 11804785

DOI: 10.1016/s0925-4773(01)00620-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8855241

Title: Cloning and characterization of four murine homeobox genes.

PubMed ID: 8855241

DOI: 10.1073/pnas.93.20.10691

PubMed ID: 15326356

Title: NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.

PubMed ID: 15326356

DOI: 10.1126/science.1099755

PubMed ID: 16997917

Title: Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters.

PubMed ID: 16997917

DOI: 10.1074/jbc.m604008200

PubMed ID: 17701902

Title: NOBOX homeobox mutation causes premature ovarian failure.

PubMed ID: 17701902

DOI: 10.1086/519496

Sequence Information:

Length: 527
Mass: 57565
Checksum: 1B6AF1323F785290
Sequence:

MEPTEKLCKK MQGQEAGDKP RTAALETEGP LQDSALPIQD DQDKQSSLPR ASLGKRPLSK 
TSEELMDAGT CRVHKAPTAA ACGPQSEEEG CSPPERKAES LKPSISAVPG QATAGSLNSH 
EGDLKKESLE VTCQFRKKTR TLYRSDQLEE LERIFQEDHY PDSDKRHEIS QMVGVTPQRI 
MVWFQNRRAK WRKVEKLNEK ETKNGPAAPS ADSSQHRSAP ELLDPMPTDL EPGPVPPENI 
LDVFPEPPML LTSEQTLTPF QNNEGAERVA VTPPLLSPPP IRRANLPLPL GPVQTPQVLP 
PMRDVPGSDS IYKDKAYVSW GTSIASPPTY SNLEDLGSQD YQASSQLGSF QLSQAPHLPL 
FPSLQSQFPY LPPFPYPIPS SMPFLPPEDS LFSFPFGFSG DSSQDYCPGP PPGQILLQPP 
AENMGTGPWS GHCLPEPPFP RPHYPQALGQ PLGAEGYFPN LLPTPYALTM SKQSSLGLNG 
LLEGTRVETG SSLSKMSDEQ TSSSLEQPAL EEVRDKNKNS HAAGAKE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nobox

Associated with

Other Information

Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes. PubMed ID: 11804785

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and characterization of four murine homeobox genes. PubMed ID: 8855241

NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. PubMed ID: 15326356

Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters. PubMed ID: 16997917