Details for: Tnfrsf11b

Gene ID: 18383

Symbol: Tnfrsf11b

Ensembl ID: ENSMUSG00000063727

Description: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

Associated with

Other Information

Genular Protein ID: 1949632267

Symbol: TR11B_MOUSE

Name: Tumor necrosis factor receptor superfamily member 11B

UniProtKB Accession Codes:

O08712 O70202

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 15 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9108485

Title: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

PubMed ID: 9108485

DOI: 10.1016/s0092-8674(00)80209-3

PubMed ID: 9714833

Title: Structure of the mouse osteoclastogenesis inhibitory factor (OCIF) gene and its expression in embryogenesis.

PubMed ID: 9714833

DOI: 10.1016/s0378-1119(98)00295-9

PubMed ID: 10952716

Title: Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis.

PubMed ID: 10952716

DOI: 10.1084/jem.192.4.463

PubMed ID: 23039992

Title: RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor.

PubMed ID: 23039992

DOI: 10.1016/j.str.2012.08.030

Sequence Information:

  • Length: 401
  • Mass: 45923
  • Checksum: CAA6102D3B312470
  • Sequence:
    • MNKWLCCALL VLLDIIEWTT QETLPPKYLH YDPETGHQLL CDKCAPGTYL KQHCTVRRKT 
LCVPCPDHSY TDSWHTSDEC VYCSPVCKEL QSVKQECNRT HNRVCECEEG RYLEIEFCLK 
HRSCPPGSGV VQAGTPERNT VCKKCPDGFF SGETSSKAPC IKHTNCSTFG LLLIQKGNAT 
HDNVCSGNRE ATQKCGIDVT LCEEAFFRFA VPTKIIPNWL SVLVDSLPGT KVNAESVERI 
KRRHSSQEQT FQLLKLWKHQ NRDQEMVKKI IQDIDLCESS VQRHLGHSNL TTEQLLALME 
SLPGKKISPE EIERTRKTCK SSEQLLKLLS LWRIKNGDQD TLKGLMYALK HLKTSHFPKT 
VTHSLRKTMR FLHSFTMYRL YQKLFLEMIG NQVQSVKISC L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.