Details for: Sigmar1

Gene ID: 18391

Symbol: Sigmar1

Ensembl ID: ENSMUSG00000036078

Description: sigma non-opioid intracellular receptor 1

Associated with

Other Information

Genular Protein ID: 289389795

Symbol: SGMR1_MOUSE

Name: Sigma non-opioid intracellular receptor 1

UniProtKB Accession Codes:

O55242 Q9JKU9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CTD 1 ChEMBL 1 ChiTaRS 1 DNASU 1 DrugCentral 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 19 GeneTree 1 Genevisible 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 7 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 4 VEuPathDB 1 eggNOG 1 jPOST 1

Citations:

PubMed ID: 9425306

Title: Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor.

PubMed ID: 9425306

DOI: 10.1006/bbrc.1997.7840

PubMed ID: 9603192

Title: Cloning and characterization of a mouse sigma1 receptor.

PubMed ID: 9603192

DOI: 10.1046/j.1471-4159.1998.70062279.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11207432

Title: Expression of the purported sigma(1) (sigma(1)) receptor in the mammalian brain and its possible relevance in deficits induced by antagonism of the NMDA receptor complex as revealed using an antisense strategy.

PubMed ID: 11207432

DOI: 10.1016/s0891-0618(00)00106-x

PubMed ID: 11476895

Title: Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor.

PubMed ID: 11476895

DOI: 10.1016/s0167-4889(01)00117-3

PubMed ID: 11687279

Title: Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina.

PubMed ID: 11687279

DOI: 10.1016/s0169-328x(01)00249-2

PubMed ID: 11149946

Title: Regulating ankyrin dynamics: roles of sigma-1 receptors.

PubMed ID: 11149946

DOI: 10.1073/pnas.98.2.491

PubMed ID: 14622179

Title: Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.

PubMed ID: 14622179

DOI: 10.1046/j.1460-9568.2003.02950.x

PubMed ID: 12730355

Title: Sigma-1 receptors (sigma(1) binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum: roles in endoplasmic reticulum lipid compartmentalization and export.

PubMed ID: 12730355

DOI: 10.1124/jpet.103.051284

PubMed ID: 15571673

Title: Involvement of kappa-opioid receptors and sigma receptors in memory function demonstrated using an antisense strategy.

PubMed ID: 15571673

DOI: 10.1016/j.brainres.2004.10.020

PubMed ID: 15777781

Title: Formalin-induced pain is reduced in sigma(1) receptor knockout mice.

PubMed ID: 15777781

DOI: 10.1016/j.ejphar.2005.01.036

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20167253

Title: The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study.

PubMed ID: 20167253

DOI: 10.1016/j.neuroscience.2010.02.022

PubMed ID: 23332758

Title: Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine.

PubMed ID: 23332758

DOI: 10.1016/j.cell.2012.12.004

PubMed ID: 25678561

Title: Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.

PubMed ID: 25678561

DOI: 10.1093/brain/awv008

PubMed ID: 26792191

Title: The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury.

PubMed ID: 26792191

DOI: 10.1016/j.neuropharm.2016.01.015

Sequence Information:

  • Length: 223
  • Mass: 25250
  • Checksum: 54BB2F14472E3512
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GLDHELAFSR 
LIVELRRLHP GHVLPDEELQ WVFVNAGGWM GAMCILHASL SEYVLLFGTA LGSHGHSGRY 
WAEISDTIIS GTFHQWKEGT TKSEVFYPGE TVVHGPGEAT ALEWGPNTWM VEYGRGVIPS 
TLFFALADTF FSTQDYLTLF YTLRAYARGL RLELTTYLFG QDS

Genular Protein ID: 1985553681

Symbol: A2AMS0_MOUSE

Name: N/A

UniProtKB Accession Codes:

A2AMS0

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 9 HOGENOM 1 InterPro 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SMR 1 TopDownProteomics 1 UCSC 1 VEuPathDB 1

Sequence Information:

  • Length: 192
  • Mass: 21633
  • Checksum: 6C75160BF446D3BC
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GLDHELAFSR 
LIVELRRLHP GHVLPDEELQ WVFVNAGGWM GAMCILHASL SEYVLLFGTA LGSHGHSGET 
VVHGPGEATA LEWGPNTWMV EYGRGVIPST LFFALADTFF STQDYLTLFY TLRAYARGLR 
LELTTYLFGQ DS

Genular Protein ID: 848979279

Symbol: I4DCY6_MOUSE

Name: N/A

UniProtKB Accession Codes:

I4DCY6

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 InterPro 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 2 RuleBase 1 UCSC 1

Sequence Information:

  • Length: 106
  • Mass: 12063
  • Checksum: 1526929C7ECD14EB
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GLDHELAFSR 
LIVELRRLHP GHVLPDEELQ WVFVNAGGWM GAMCILHASL SETILG

Genular Protein ID: 171317651

Symbol: B7ZJH7_MOUSE

Name: N/A

UniProtKB Accession Codes:

B7ZJH7

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 InterPro 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 UCSC 1

Sequence Information:

  • Length: 185
  • Mass: 21177
  • Checksum: 250F7533FD8CC7A6
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GLDHELAFSR 
LIVELRRLHP GHVLPDEELQ WVFVNAGGWM GAMCILHASL SEYVLLFGTA LGSHGHSGRY 
WAEISDTIIS GTFHQWKEGT TKSEVFYPAD TFFSTQDYLT LFYTLRAYAR GLRLELTTYL 
FGQDS

Genular Protein ID: 516454510

Symbol: B7ZJH8_MOUSE

Name: N/A

UniProtKB Accession Codes:

B7ZJH8

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 InterPro 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1

Sequence Information:

  • Length: 114
  • Mass: 13002
  • Checksum: 91D44C9B5B03CDE7
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFYPG ETVVHGPGEA TALEWGPNTW 
MVEYGRGVIP STLFFALADT FFSTQDYLTL FYTLRAYARG LRLELTTYLF GQDS

Genular Protein ID: 894352847

Symbol: B7ZJH9_MOUSE

Name: N/A

UniProtKB Accession Codes:

B7ZJH9

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 InterPro 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 TopDownProteomics 1 UCSC 1

Sequence Information:

  • Length: 156
  • Mass: 17875
  • Checksum: C750213E5CB04D31
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GRYWAEISDT 
IISGTFHQWK EGTTKSEVFY PGETVVHGPG EATALEWGPN TWMVEYGRGV IPSTLFFALA 
DTFFSTQDYL TLFYTLRAYA RGLRLELTTY LFGQDS

Genular Protein ID: 932140880

Symbol: B7ZJH6_MOUSE

Name: N/A

UniProtKB Accession Codes:

B7ZJH6

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 InterPro 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 UCSC 1

Sequence Information:

  • Length: 218
  • Mass: 24450
  • Checksum: 0585D18BDED24845
  • Sequence:
    • MPWAAGRRWA WITLILTIIA VLIQAAWLWL GTQNFVFSRE EIAQLARQYA GLDHELAFSR 
LIVELRRLHP GHVLPDEELQ WVFVNAGGWM GAMCILHASL SEYVLLFGTA LGSHGHSGRY 
WAEISDTIIS GTFHQWKEGT TKSEVFYPAP RTTSHSSIPF GPMPGASGLS LPPTSLAKTP 
DQPGLKEDLW MDRSAAGPHP SLYSLELIFR QQRIPCRY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.