Genular: Defining Cellular Identity and Function

Details for: Slc22a6

Gene ID: 18399

Symbol: Slc22a6

Ensembl ID: ENSMUSG00000024650

Description: solute carrier family 22 (organic anion transporter), member 6

Associated with

Organic cation/anion/zwitterion transport
(R-MMU-549132)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-MMU-425366)
Transport of small molecules
(R-MMU-382551)
Alpha-ketoglutarate transmembrane transporter activity
(GO:0015139)
Alpha-ketoglutarate transport
(GO:0015742)
Antiporter activity
(GO:0015297)
Basal plasma membrane
(GO:0009925)
Basolateral plasma membrane
(GO:0016323)
Caveola
(GO:0005901)
Chloride ion binding
(GO:0031404)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Monoatomic anion transport
(GO:0006820)
Organic anion transmembrane transporter activity
(GO:0008514)
Organic anion transport
(GO:0015711)
Plasma membrane
(GO:0005886)
Prostaglandin transmembrane transporter activity
(GO:0015132)
Prostaglandin transport
(GO:0015732)
Protein-containing complex
(GO:0032991)
Renal tubular secretion
(GO:0097254)
Sodium-independent organic anion transmembrane transporter activity
(GO:0015347)
Sodium-independent organic anion transport
(GO:0043252)
Solute:inorganic anion antiporter activity
(GO:0005452)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)
Xenobiotic transmembrane transporter activity
(GO:0042910)

Other Information

Proteins

Kidney-specific transport protein

Genular Protein ID: 2965738671

Symbol: S22A6_MOUSE

Name: Kidney-specific transport protein

UniProtKB Accession Codes:

Q8VC69 Q61185

Database IDs:

Citations:

PubMed ID: 9045672

Title: Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney.

PubMed ID: 9045672

DOI: 10.1074/jbc.272.10.6471

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9880528

Title: Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.

PubMed ID: 9880528

DOI: 10.1074/jbc.274.3.1519

PubMed ID: 10744714

Title: Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells.

PubMed ID: 10744714

DOI: 10.1074/jbc.275.14.10278

PubMed ID: 14979872

Title: Cysteine residues in the organic anion transporter mOAT1.

PubMed ID: 14979872

DOI: 10.1042/bj20031724

PubMed ID: 14749323

Title: Role of glycosylation in the organic anion transporter OAT1.

PubMed ID: 14749323

DOI: 10.1074/jbc.m400197200

PubMed ID: 15944205

Title: Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites.

PubMed ID: 15944205

DOI: 10.1152/ajpcell.00619.2004

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 545
Mass: 60013
Checksum: 827782E115705C77
Sequence:

MAFNDLLKQV GGVGRFQLIQ VTMVVAPLLL MASHNTLQNF TAAIPAHHCR PPANANLSKD 
GGLEAWLPLD KQGRPESCLR FPFPHNGTEA NGTGVTEPCL DGWVYDNSTF PSTIVTEWNL 
VCSHRAFRQL AQSLFMVGVL LGAMMFGYLA DRLGRRKVLI LNYLQTAVSG TCAAYAPNYT 
VYCIFRLLSG MSLASIAINC MTLNMEWMPI HTRAYVGTLI GYVYSLGQFL LAGIAYAVPH 
WRHLQLAVSV PFFVAFIYSW FFIESARWYS SSGRLDLTLR ALQRVARING KQEEGAKLSI 
EVLQTSLQKE LTLNKGQASA MELLRCPTLR RLFLCLSMLW FATSFAYYGL VMDLQGFGVS 
MYLIQVIFGA VDLPAKFVCF LVINSMGRRP AQLASLLLAG ICILVNGIIP RGHTIIRTSL 
AVLGKGCLAS SFNCIFLYTG ELYPTMIRQT GLGMGSTMAR VGSIVSPLIS MTAEFYPSIP 
LFIFGAVPVA ASAVTALLPE TLGQPLPDTV QDLKSRSRGK QKQQQLEQQK QMIPLQVSTQ 
EKNGL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc22a6

Associated with

Other Information

Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. PubMed ID: 9045672

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells. PubMed ID: 9880528

Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells. PubMed ID: 10744714

Cysteine residues in the organic anion transporter mOAT1. PubMed ID: 14979872

Role of glycosylation in the organic anion transporter OAT1. PubMed ID: 14749323

Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. PubMed ID: 15944205

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079