Genular: Defining Cellular Identity and Function

Details for: Otc

Gene ID: 18416

Symbol: Otc

Ensembl ID: ENSMUSG00000031173

Description: ornithine transcarbamylase

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Mitochondrial protein import
(R-MMU-1268020)
Protein localization
(R-MMU-9609507)
Amino acid binding
(GO:0016597)
Amino acid biosynthetic process
(GO:0008652)
Amino acid metabolic process
(GO:0006520)
Ammonium homeostasis
(GO:0097272)
Arginine biosynthetic process
(GO:0006526)
Arginine biosynthetic process via ornithine
(GO:0042450)
Carboxyl- or carbamoyltransferase activity
(GO:0016743)
Citrulline biosynthetic process
(GO:0019240)
Identical protein binding
(GO:0042802)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrion
(GO:0005739)
Monoatomic anion homeostasis
(GO:0055081)
Ornithine carbamoyltransferase activity
(GO:0004585)
Ornithine catabolic process
(GO:0006593)
Ornithine metabolic process
(GO:0006591)
Phosphate ion binding
(GO:0042301)
Phospholipid binding
(GO:0005543)
Transferase activity
(GO:0016740)
Urea cycle
(GO:0000050)

Other Information

Proteins

Ornithine carbamoyltransferase, mitochondrial

Genular Protein ID: 2431693032

Symbol: OTC_MOUSE

Name: Ornithine carbamoyltransferase, mitochondrial

UniProtKB Accession Codes:

P11725

Database IDs:

Citations:

PubMed ID: 3603027

Title: The molecular basis of the sparse fur mouse mutation.

PubMed ID: 3603027

DOI: 10.1126/science.3603027

PubMed ID: 2831503

Title: The genetic structure of mouse ornithine transcarbamylase.

PubMed ID: 2831503

DOI: 10.1093/nar/16.4.1593

PubMed ID: 3011788

Title: The 5' flanking region of the ornithine transcarbamylase gene contains DNA sequences regulating tissue-specific expression.

PubMed ID: 3011788

DOI: 10.1016/s0021-9258(19)57435-x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 354
Mass: 39765
Checksum: 33BBE5D1E88AA196
Sequence:

MLSNLRILLN NAALRKGHTS VVRHFWCGKP VQSQVQLKGR DLLTLKNFTG EEIQYMLWLS 
ADLKFRIKQK GEYLPLLQGK SLGMIFEKRS TRTRLSTETG FALLGGHPSF LTTQDIHLGV 
NESLTDTARV LSSMTDAVLA RVYKQSDLDT LAKEASIPIV NGLSDLYHPI QILADYLTLQ 
EHYGSLKGLT LSWIGDGNNI LHSIMMSAAK FGMHLQAATP KGYEPDPNIV KLAEQYAKEN 
GTKLSMTNDP LEAARGGNVL ITDTWISMGQ EDEKKKRLQA FQGYQVTMKT AKVAASDWTF 
LHCLPRKPEE VDDEVFYSPR SLVFPEAENR KWTIMAVMVS LLTDYSPVLQ KPKF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Otc

Associated with

Other Information

The molecular basis of the sparse fur mouse mutation. PubMed ID: 3603027

The genetic structure of mouse ornithine transcarbamylase. PubMed ID: 2831503

The 5' flanking region of the ornithine transcarbamylase gene contains DNA sequences regulating tissue-specific expression. PubMed ID: 3011788

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337