Details for: Otp

Gene ID: 18420

Symbol: Otp

Ensembl ID: ENSMUSG00000021685

Description: orthopedia homeobox

Associated with

Other Information

Genular Protein ID: 1942319568

Symbol: OTP_MOUSE

Name: Homeobox protein orthopedia

UniProtKB Accession Codes:

O09113

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 1 Ensembl 1 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 7913821

Title: Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila.

PubMed ID: 7913821

DOI: 10.1016/0896-6273(94)90461-8

PubMed ID: 10557207

Title: Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene.

PubMed ID: 10557207

DOI: 10.1101/gad.13.21.2787

PubMed ID: 11071765

Title: The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus.

PubMed ID: 11071765

DOI: 10.1006/dbio.2000.9902

PubMed ID: 17481897

Title: Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development.

PubMed ID: 17481897

DOI: 10.1016/j.cub.2007.04.003

Sequence Information:

  • Length: 325
  • Mass: 34159
  • Checksum: 429E3A91E0A9BA5F
  • Sequence:
    • MLSHADLLDA RLGMKDAAEL LGHREAVKCR LGVGGSDPGG HPGDLAPNSD PVEGATLLPG 
EDITTVGSTP ASLAVSAKDP DKQPGPQGGP NPSQAGQQQG QQKQKRHRTR FTPAQLNELE 
RSFAKTHYPD IFMREELALR IGLTESRVQV WFQNRRAKWK KRKKTTNVFR APGTLLPTPG 
LPQFPSAAAA AAAAMGDSLC SFHANDTRWA AAAMPGVSQL PLPPALGRQQ AMAQSLSQCS 
LAAGPPPNSM GLSNSLAGSN GAGLQSHLYQ PAFPGMVPAS LPGPSNVSGS PQLCSSPDSS 
DVWRGTSIAS LRRKALEHTV SMSFT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.