Details for: Otx1

Gene ID: 18423

Symbol: Otx1

Ensembl ID: ENSMUSG00000005917

Description: orthodenticle homeobox 1

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Diencephalon morphogenesis
    (GO:0048852)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Forebrain development
    (GO:0030900)
  • Inner ear morphogenesis
    (GO:0042472)
  • Metencephalon development
    (GO:0022037)
  • Midbrain development
    (GO:0030901)
  • Multicellular organism development
    (GO:0007275)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 381576215

Symbol: OTX1_MOUSE

Name: Homeobox protein OTX1

UniProtKB Accession Codes:

P80205

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8101484

Title: A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

PubMed ID: 8101484

DOI: 10.1002/j.1460-2075.1993.tb05935.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1353865

Title: Nested expression domains of four homeobox genes in developing rostral brain.

PubMed ID: 1353865

DOI: 10.1038/358687a0

Sequence Information:

  • Length: 355
  • Mass: 37532
  • Checksum: DA5136D9D4FC948F
  • Sequence:
    • MMSYLKQPPY GMNGLGLAGP AMDLLHPSVG YPATPRKQRR ERTTFTRSQL DVLEALFAKT 
RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQSG NGTKTRPVKK KSSPVRESSG 
SESSGQFTPP AVSSSASSSS SASSASANPA AAAAAGLGGN PVAAASSLST PTASSIWSPA 
SISPGSAPTS VSVPEPLAAP SNASCMQRSV AAGAATAAAS YPMSYGQGGS YGQGYPAPSS 
SYFGGVDCSS YLAPMHSHHH PHQLSPMAPS SMAGHHHHHP HAHHPLSQSS GHHHHHHHHH 
HHQGYGGSGL AFNSADCLDY KEPAAAAASS AWKLNFNSPD CLDYKDQASW RFQVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.