Genular: Defining Cellular Identity and Function

Details for: P2rx1

Gene ID: 18436

Symbol: P2rx1

Ensembl ID: ENSMUSG00000020787

Description: purinergic receptor P2X, ligand-gated ion channel, 1

Associated with

Elevation of cytosolic ca2+ levels
(R-MMU-139853)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Platelet calcium homeostasis
(R-MMU-418360)
Platelet homeostasis
(R-MMU-418346)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Apoptotic process
(GO:0006915)
Atp binding
(GO:0005524)
Calcium ion transmembrane transport
(GO:0070588)
Ceramide biosynthetic process
(GO:0046513)
Establishment of localization in cell
(GO:0051649)
External side of plasma membrane
(GO:0009897)
Extracellularly atp-gated monoatomic cation channel activity
(GO:0004931)
Glutamatergic synapse
(GO:0098978)
Identical protein binding
(GO:0042802)
Insemination
(GO:0007320)
Membrane
(GO:0016020)
Monoatomic cation channel activity
(GO:0005261)
Monoatomic cation transmembrane transport
(GO:0098655)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Neuronal action potential
(GO:0019228)
Nucleotide binding
(GO:0000166)
Organic cyclic compound binding
(GO:0097159)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of calcium ion import across plasma membrane
(GO:1905665)
Positive regulation of monoatomic ion transport
(GO:0043270)
Postsynaptic membrane
(GO:0045211)
Presynaptic active zone membrane
(GO:0048787)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Purinergic nucleotide receptor activity
(GO:0001614)
Regulation of blood pressure
(GO:0008217)
Regulation of calcium ion transport
(GO:0051924)
Regulation of presynaptic cytosolic calcium ion concentration
(GO:0099509)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of synaptic vesicle exocytosis
(GO:2000300)
Regulation of vascular associated smooth muscle contraction
(GO:0003056)
Regulation of vasoconstriction
(GO:0019229)
Response to atp
(GO:0033198)
Response to organic substance
(GO:0010033)
Serotonin secretion by platelet
(GO:0002554)
Suramin binding
(GO:0043924)
Synaptic transmission, glutamatergic
(GO:0035249)

Other Information

Proteins

P2X purinoceptor 1

Genular Protein ID: 3381884726

Symbol: P2RX1_MOUSE

Name: P2X purinoceptor 1

UniProtKB Accession Codes:

P51576 Q5SRU4

Database IDs:

Citations:

PubMed ID: 8834001

Title: Characterization and chromosomal localization of a human P2X receptor from the urinary bladder.

PubMed ID: 8834001

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 399
Mass: 44851
Checksum: 8CBF6B97F569472E
Sequence:

MARRLQDELS AFFFEYDTPR MVLVRNKKVG VIFRLIQLVV LVYVIGWVFV YEKGYQTSSG 
LISSVSVKLK GLAVTQLQGL GPQVWDVADY VFPAHGDSSF VVMTNFIMTP QQAQGHCAEN 
PEGGICQDDS GCTPGKAERK AQGIRTGNCV PFNGTVKTCE IFGWCPVEVD DKIPSPALLH 
EAENFTLFIK NSISFPRFKV NRRNLVEEVN GTYMKKCLYH KILHPLCPVF SLGYVVRESG 
QDFRSLAEKG GVVGITIDWE CDLDWHVRHC KPIYQFHGLY GEKNLSPGFN FRFARHFVQN 
GTNRRHLFKV FGIRFDILVD GKAGKFDIIP TMTTIGSGIG IFGVATVLCD LLLLHILPKR 
HYYKQKKFKY AEDMGPGEGE RDPAATSSTL GLQENMRTS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.