Genular: Defining Cellular Identity and Function

Details for: P2ry1

Gene ID: 18441

Symbol: P2ry1

Ensembl ID: ENSMUSG00000027765

Description: purinergic receptor P2Y, G-protein coupled 1

Associated with

Adp signalling through p2y purinoceptor 1
(R-MMU-418592)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hemostasis
(R-MMU-109582)
Nucleotide-like (purinergic) receptors
(R-MMU-418038)
P2y receptors
(R-MMU-417957)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Signal amplification
(R-MMU-392518)
Signaling by gpcr
(R-MMU-372790)
A1 adenosine receptor binding
(GO:0031686)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adp binding
(GO:0043531)
Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Basolateral plasma membrane
(GO:0016323)
Blood vessel diameter maintenance
(GO:0097746)
Cell body
(GO:0044297)
Cellular response to organic cyclic compound
(GO:0071407)
Cellular response to purine-containing compound
(GO:0071415)
Cilium
(GO:0005929)
Dendrite
(GO:0030425)
Eating behavior
(GO:0042755)
Establishment of localization in cell
(GO:0051649)
Glial cell migration
(GO:0008347)
Glutamatergic synapse
(GO:0098978)
G protein-coupled adenosine receptor signaling pathway
(GO:0001973)
G protein-coupled adp receptor activity
(GO:0001621)
G protein-coupled atp receptor activity
(GO:0045031)
G protein-coupled purinergic nucleotide receptor activity
(GO:0045028)
G protein-coupled purinergic nucleotide receptor signaling pathway
(GO:0035589)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Membrane
(GO:0016020)
Monoatomic ion transport
(GO:0006811)
Negative regulation of norepinephrine secretion
(GO:0010700)
Nucleotide binding
(GO:0000166)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of hormone secretion
(GO:0046887)
Positive regulation of inositol trisphosphate biosynthetic process
(GO:0032962)
Positive regulation of monoatomic ion transport
(GO:0043270)
Positive regulation of penile erection
(GO:0060406)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Postsynaptic density
(GO:0014069)
Postsynaptic membrane
(GO:0045211)
Presynaptic active zone membrane
(GO:0048787)
Protein heterodimerization activity
(GO:0046982)
Protein localization to plasma membrane
(GO:0072659)
Regulation of cell shape
(GO:0008360)
Regulation of presynaptic cytosolic calcium ion concentration
(GO:0099509)
Regulation of synaptic vesicle exocytosis
(GO:2000300)
Relaxation of muscle
(GO:0090075)
Response to mechanical stimulus
(GO:0009612)
Scaffold protein binding
(GO:0097110)
Signal transduction
(GO:0007165)
Signal transduction involved in regulation of gene expression
(GO:0023019)

Other Information

Proteins

P2Y purinoceptor 1
Q8BMJ5_MOUSE

Genular Protein ID: 963053519

Symbol: P2RY1_MOUSE

Name: P2Y purinoceptor 1

UniProtKB Accession Codes:

P49650

Database IDs:

Citations:

PubMed ID: 7779087

Title: Cloning of rat and mouse P2Y purinoceptors.

PubMed ID: 7779087

DOI: 10.1006/bbrc.1995.1798

PubMed ID: 10606627

Title: Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice.

PubMed ID: 10606627

DOI: 10.1172/jci8399

Sequence Information:

Length: 373
Mass: 42213
Checksum: 944125E9F4560BB3
Sequence:

MTEVPWSVVP NGTDAAFLAG LGSLWGNSTV ASTAAVSSSF QCALTKTGFQ FYYLPAVYIL 
VFIIGFLGNS VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG 
DAMCKLQRFI FHVNLYGSIL FLTCISAHRY SGVVYPLKSL GRLKKKNAIY VSVLVWLIVV 
VAISPILFYS GTGTRKNKTV TCYDTTSNDY LRSYFIYSMC TTVAMFCIPL VLILGCYGLI 
VKALIYNDLD NSPLRRKSIY LVIIVLTVFA VSYIPFHVMK TMNLRARLDF QTPEMCDFND 
RVYATYQVTR GLASLNSCVD PILYFLAGDT FRRRLSRATR KASRRSEANL QSKSEEMTLN 
ILSEFKQNGD TSL

Genular Protein ID: 2159964210

Symbol: Q8BMJ5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BMJ5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 373
Mass: 42229
Checksum: BA88124B7847287C
Sequence:

MTEVPWSVVP NGTDAAFLAG LGSLWGNSTV ASTAAVSSSF QCALTKTGFQ FYYLPAVYIL 
VFIIGFLGNS VAIWMYVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG 
DAMCKLQRFI FHVNLYGSIL FLTCISAHRY SGVVYPLKSL GRLKKKNAIY VSVLVWLIVV 
VAISPILFYS GTGTRKNKTV TCYDTTSNDY LRSYFIYSMC TTVAMFCIPL VLILGCYGLI 
VKALIYNDLD NSPLRRKSIY LVIIVLTVFA VSYIPFHVMK TMNLRARLDF QTPEMCDFND 
RVYATYQVTR GLASLNSCVD PILYFLAGDT FRRRLSRATR KASRRSEANL QSKSEEMTLN 
ILSEFKQNGD TSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: P2ry1

Associated with

Other Information

Cloning of rat and mouse P2Y purinoceptors. PubMed ID: 7779087

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. PubMed ID: 10606627

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073