Genular: Defining Cellular Identity and Function

Details for: P2ry2

Gene ID: 18442

Symbol: P2ry2

Ensembl ID: ENSMUSG00000032860

Description: purinergic receptor P2Y, G-protein coupled 2

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Metabolism of proteins
(R-MMU-392499)
Nucleotide-like (purinergic) receptors
(R-MMU-418038)
P2y receptors
(R-MMU-417957)
Signaling by gpcr
(R-MMU-372790)
Surfactant metabolism
(R-MMU-5683826)
A1 adenosine receptor binding
(GO:0031686)
Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Basolateral plasma membrane
(GO:0016323)
Blood vessel diameter maintenance
(GO:0097746)
Early endosome
(GO:0005769)
Establishment of localization in cell
(GO:0051649)
Glutamatergic synapse
(GO:0098978)
G protein-coupled purinergic nucleotide receptor activity
(GO:0045028)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled utp receptor activity
(GO:0045030)
Membrane
(GO:0016020)
Mucus secretion
(GO:0070254)
Negative regulation of ossification
(GO:0030279)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of mucus secretion
(GO:0070257)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of penile erection
(GO:0060406)
Positive regulation of prostaglandin secretion
(GO:0032308)
Positive regulation of smooth muscle cell migration
(GO:0014911)
Presynaptic active zone membrane
(GO:0048787)
Regulation of presynaptic cytosolic calcium ion concentration
(GO:0099509)
Regulation of synaptic vesicle exocytosis
(GO:2000300)
Signal transduction
(GO:0007165)

Other Information

Proteins

P2Y purinoceptor 2
A0A0R4J289_MOUSE

Genular Protein ID: 334212804

Symbol: P2RY2_MOUSE

Name: P2Y purinoceptor 2

UniProtKB Accession Codes:

P35383 O09031 Q9CPZ4

Database IDs:

Citations:

PubMed ID: 7685114

Title: Expression cloning of an ATP receptor from mouse neuroblastoma cells.

PubMed ID: 7685114

DOI: 10.1073/pnas.90.11.5113

PubMed ID: 8739319

Title: Expression cloning and signal transduction pathway of P2U receptor in mammary tumor cells.

PubMed ID: 8739319

DOI: 10.1159/000109169

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7876172

Title: Site-directed mutagenesis of P2U purinoceptors. Positively charged amino acids in transmembrane helices 6 and 7 affect agonist potency and specificity.

PubMed ID: 7876172

DOI: 10.1074/jbc.270.9.4185

Sequence Information:

Length: 373
Mass: 42175
Checksum: 590BBE502E41B3AE
Sequence:

MAADLEPWNS TINGTWEGDE LGYKCRFNED FKYVLLPVSY GVVCVLGLCL NVVALYIFLC 
RLKTWNASTT YMFHLAVSDS LYAASLPLLV YYYARGDHWP FSTVLCKLVR FLFYTNLYCS 
ILFLTCISVH RCLGVLRPLH SLRWGRARYA RRVAAVVWVL VLACQAPVLY FVTTSVRGTR 
ITCHDTSARE LFSHFVAYSS VMLGLLFAVP FSVILVCYVL MARRLLKPAY GTTGGLPRAK 
RKSVRTIALV LAVFALCFLP FHVTRTLYYS FRSLDLSCHT LNAINMAYKI TRPLASANSC 
LDPVLYFLAG QRLVRFARDA KPPTEPTPSP QARRKLGLHR PNRTVRKDLS VSSDDSRRTE 
STPAGSETKD IRL

Genular Protein ID: 1452852429

Symbol: A0A0R4J289_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J289

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 373
Mass: 42189
Checksum: E4BD653D895DCE8F
Sequence:

MAADLEPWNS TINGTWEGDE LGYKCRFNED FKYVLLPVSY GVVCVLGLCL NVVALYIFLC 
RLKTWNASTT YMFHLAVSDS LYAASLPLLV YYYARGDHWP FSTVLCKLVR FLFYTNLYCS 
ILFLTCISVH RCLGVLRPLH SLRWGRARYA RRVAAVVWVL VLACQAPVLY FVTTSVRGTR 
ITCHDTSARE LFSHFVAYSS VMLGLLFAVP FSVILVCYVL MARRLLKPAY GTTGGLPRAK 
RKSVRTIALV LAVFALCFLP FHLTRTLYYS FRSLDLSCHT LNAINMAYKI TRPLASANSC 
LDPVLYFLAG QRLVRFARDA KPPTEPTPSP QARRKLGLHR PNRTVRKDLS VSSDDSRRTE 
STPAGSETKD IRL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: P2ry2

Associated with

Other Information

Expression cloning of an ATP receptor from mouse neuroblastoma cells. PubMed ID: 7685114

Expression cloning and signal transduction pathway of P2U receptor in mammary tumor cells. PubMed ID: 8739319

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Site-directed mutagenesis of P2U purinoceptors. Positively charged amino acids in transmembrane helices 6 and 7 affect agonist potency and specificity. PubMed ID: 7876172