Genular: Defining Cellular Identity and Function

Details for: Prdx1

Gene ID: 18477

Symbol: Prdx1

Ensembl ID: ENSMUSG00000028691

Description: peroxiredoxin 1

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Keap1-nfe2l2 pathway
(R-MMU-9755511)
Nfe2l2 regulating anti-oxidant/detoxification enzymes
(R-MMU-9818027)
Nuclear events mediated by nfe2l2
(R-MMU-9759194)
Rna polymerase ii transcription
(R-MMU-73857)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Antioxidant activity
(GO:0016209)
Canonical nf-kappab signal transduction
(GO:0007249)
Cell redox homeostasis
(GO:0045454)
Cellular response to stress
(GO:0033554)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Erythrocyte homeostasis
(GO:0034101)
Euchromatin
(GO:0000791)
Fibroblast proliferation
(GO:0048144)
Heme binding
(GO:0020037)
Hydrogen peroxide catabolic process
(GO:0042744)
Identical protein binding
(GO:0042802)
Leukocyte activation
(GO:0045321)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Natural killer cell activation
(GO:0030101)
Natural killer cell mediated cytotoxicity
(GO:0042267)
Nucleus
(GO:0005634)
Oxidoreductase activity
(GO:0016491)
Peroxidase activity
(GO:0004601)
Peroxiredoxin activity
(GO:0051920)
Peroxisomal matrix
(GO:0005782)
Protein binding
(GO:0005515)
Regulation of non-canonical nf-kappab signal transduction
(GO:1901222)
Regulation of stress-activated mapk cascade
(GO:0032872)
Removal of superoxide radicals
(GO:0019430)
Response to oxidative stress
(GO:0006979)
Response to reactive oxygen species
(GO:0000302)
Thioredoxin-dependent peroxiredoxin activity
(GO:0140824)
Thioredoxin peroxidase activity
(GO:0008379)

Other Information

Proteins

Peroxiredoxin-1

Genular Protein ID: 641832603

Symbol: PRDX1_MOUSE

Name: Peroxiredoxin-1

UniProtKB Accession Codes:

P35700 Q3UBV4 Q9CWI2

Database IDs:

Citations:

PubMed ID: 8360158

Title: Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein.

PubMed ID: 8360158

DOI: 10.1016/s0021-9258(17)46676-2

PubMed ID: 8089076

Title: Cloning and characterization of OSF-3, a new member of the MER5 family, expressed in mouse osteoblastic cells.

PubMed ID: 8089076

DOI: 10.1093/oxfordjournals.jbchem.a124388

PubMed ID: 10548725

Title: Characterization of mouse peroxiredoxin I genomic DNA and its expression.

PubMed ID: 10548725

DOI: 10.1016/s0378-1119(99)00413-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19766572

Title: The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.

PubMed ID: 19766572

DOI: 10.1016/j.cell.2009.06.042

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21969592

Title: Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.

PubMed ID: 21969592

DOI: 10.1073/pnas.1103318108

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 199
Mass: 22176
Checksum: BEF5C995A86124D1
Sequence:

MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS 
DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK 
ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG 
SDTIKPDVNK SKEYFSKQK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prdx1

Associated with

Other Information

Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein. PubMed ID: 8360158

Cloning and characterization of OSF-3, a new member of the MER5 family, expressed in mouse osteoblastic cells. PubMed ID: 8089076

Characterization of mouse peroxiredoxin I genomic DNA and its expression. PubMed ID: 10548725

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2. PubMed ID: 19766572

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition. PubMed ID: 21969592

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337