Genular: Defining Cellular Identity and Function

Details for: Reg3b

Gene ID: 18489

Symbol: Reg3b

Ensembl ID: ENSMUSG00000071356

Description: regenerating islet-derived 3 beta

Associated with

Antimicrobial peptides
(R-MMU-6803157)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Acute-phase response
(GO:0006953)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Apical part of cell
(GO:0045177)
Carbohydrate binding
(GO:0030246)
Collagen-containing extracellular matrix
(GO:0062023)
Defense response to gram-negative bacterium
(GO:0050829)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth factor binding
(GO:0019838)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Inflammatory response
(GO:0006954)
Metal ion binding
(GO:0046872)
Negative regulation of cellular response to oxidative stress
(GO:1900408)
Oligosaccharide binding
(GO:0070492)
Peptidoglycan binding
(GO:0042834)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex
(GO:0032991)
Response to bacterium
(GO:0009617)
Response to peptide hormone
(GO:0043434)
Signaling receptor activity
(GO:0038023)
Zymogen granule
(GO:0042588)

Other Information

Proteins

Pancreatitis-associated protein 1

Genular Protein ID: 519274749

Symbol: REG3B_MOUSE

Name: Pancreatitis-associated protein 1

UniProtKB Accession Codes:

P35230

Database IDs:

Citations:

PubMed ID: 7679928

Title: Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP).

PubMed ID: 7679928

DOI: 10.1016/0167-4781(93)90290-t

PubMed ID: 9055810

Title: Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma.

PubMed ID: 9055810

DOI: 10.1016/s0378-1119(96)00589-6

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21694778

Title: Salmonella-induced mucosal lectin RegIII? kills competing gut microbiota.

PubMed ID: 21694778

DOI: 10.1371/journal.pone.0020749

PubMed ID: 22252863

Title: Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice.

PubMed ID: 22252863

DOI: 10.1128/iai.06165-11

PubMed ID: 34099862

Title: REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway.

PubMed ID: 34099862

DOI: 10.1038/s42003-021-02193-z

Sequence Information:

Length: 175
Mass: 19476
Checksum: 44B3101171E79775
Sequence:

MLPPTACSVM SWMLLSCLML LSQVQGEDSL KNIPSARISC PKGSQAYGSY CYALFQIPQT 
WFDAELACQK RPGGHLVSVL NSAEASFLSS MVKRTGNSYQ YTWIGLHDPT LGAEPNGGGW 
EWSNNDVMNY FNWERNPSTA LDRAFCGSLS RASGFLKWRD MTCEVKLPYV CKFTG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Reg3b

Associated with

Other Information

Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). PubMed ID: 7679928

Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma. PubMed ID: 9055810

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Salmonella-induced mucosal lectin RegIII? kills competing gut microbiota. PubMed ID: 21694778

Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice. PubMed ID: 22252863

REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. PubMed ID: 34099862