Details for: AGTR1

Gene ID: 185

Symbol: AGTR1

Ensembl ID: ENSG00000144891

Description: angiotensin II receptor type 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.3949
    Cell Significance Index: -8.0200
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 6.0217
    Cell Significance Index: 62.3000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 5.6896
    Cell Significance Index: 38.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.9823
    Cell Significance Index: 64.6100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 2.3036
    Cell Significance Index: 19.3500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.2161
    Cell Significance Index: 59.3800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.1098
    Cell Significance Index: 35.5400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.0649
    Cell Significance Index: 12.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.0413
    Cell Significance Index: 39.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.8747
    Cell Significance Index: 372.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.7543
    Cell Significance Index: 79.5200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.1380
    Cell Significance Index: 57.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7941
    Cell Significance Index: 78.5600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7292
    Cell Significance Index: 658.4100
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.7045
    Cell Significance Index: 9.5000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.5714
    Cell Significance Index: 11.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5702
    Cell Significance Index: 108.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5581
    Cell Significance Index: 11.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4314
    Cell Significance Index: 46.9300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4298
    Cell Significance Index: 69.9100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4287
    Cell Significance Index: 12.2900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3887
    Cell Significance Index: 12.4500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3013
    Cell Significance Index: 18.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2601
    Cell Significance Index: 17.9900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.2345
    Cell Significance Index: 3.7200
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: 0.1380
    Cell Significance Index: 0.6600
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.1049
    Cell Significance Index: 1.4900
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 0.0996
    Cell Significance Index: 0.4600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0794
    Cell Significance Index: 1.1400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0271
    Cell Significance Index: 0.4000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0131
    Cell Significance Index: 0.2100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0083
    Cell Significance Index: 0.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0065
    Cell Significance Index: 0.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0023
    Cell Significance Index: 1.5700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0020
    Cell Significance Index: -0.5700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0050
    Cell Significance Index: -9.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0074
    Cell Significance Index: -13.7200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0090
    Cell Significance Index: -13.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0129
    Cell Significance Index: -9.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0130
    Cell Significance Index: -8.2400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0147
    Cell Significance Index: -10.8800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0173
    Cell Significance Index: -10.7800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0176
    Cell Significance Index: -9.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0195
    Cell Significance Index: -10.6500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0212
    Cell Significance Index: -2.4700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0239
    Cell Significance Index: -8.5900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0254
    Cell Significance Index: -4.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0268
    Cell Significance Index: -12.1800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0372
    Cell Significance Index: -0.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0439
    Cell Significance Index: -8.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0454
    Cell Significance Index: -7.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0460
    Cell Significance Index: -9.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0473
    Cell Significance Index: -1.7900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0568
    Cell Significance Index: -0.9500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0568
    Cell Significance Index: -4.2300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0602
    Cell Significance Index: -8.7600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0614
    Cell Significance Index: -7.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0629
    Cell Significance Index: -6.4300
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0641
    Cell Significance Index: -0.7800
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0665
    Cell Significance Index: -0.6900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0674
    Cell Significance Index: -1.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0697
    Cell Significance Index: -9.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0704
    Cell Significance Index: -9.6700
  • Cell Name: fibroblast of the aortic adventitia (CL0002547)
    Fold Change: -0.0842
    Cell Significance Index: -0.8500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0881
    Cell Significance Index: -10.1000
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.0950
    Cell Significance Index: -0.9800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0952
    Cell Significance Index: -9.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0979
    Cell Significance Index: -4.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1004
    Cell Significance Index: -4.4400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1118
    Cell Significance Index: -1.8800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1325
    Cell Significance Index: -8.3500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1338
    Cell Significance Index: -9.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1364
    Cell Significance Index: -10.4700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1397
    Cell Significance Index: -3.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1424
    Cell Significance Index: -7.9900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1492
    Cell Significance Index: -7.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1501
    Cell Significance Index: -9.2000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1506
    Cell Significance Index: -4.2100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1534
    Cell Significance Index: -2.7100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1540
    Cell Significance Index: -4.0500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1593
    Cell Significance Index: -9.7900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1669
    Cell Significance Index: -2.7500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.1732
    Cell Significance Index: -1.6700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1847
    Cell Significance Index: -8.6100
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.1919
    Cell Significance Index: -1.1100
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: -0.2351
    Cell Significance Index: -1.4400
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.2425
    Cell Significance Index: -2.9500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2438
    Cell Significance Index: -12.6700
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.2446
    Cell Significance Index: -2.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2452
    Cell Significance Index: -8.5200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2576
    Cell Significance Index: -2.8000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2578
    Cell Significance Index: -9.0300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2845
    Cell Significance Index: -8.3800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2851
    Cell Significance Index: -9.0800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2899
    Cell Significance Index: -7.7400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2966
    Cell Significance Index: -9.7100
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.2984
    Cell Significance Index: -5.1000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3008
    Cell Significance Index: -6.2400
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.3075
    Cell Significance Index: -4.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The AGTR1 gene encodes a G protein-coupled receptor (GPCR) that is activated by angiotensin II, a potent vasoconstrictor peptide produced by the renin-angiotensin system. The AGTR1 receptor is characterized by its high affinity for angiotensin II, which binding to the receptor triggers a conformational change that activates the receptor's intrinsic G protein-coupled receptor signaling pathway. This pathway involves the activation of Gq proteins, which in turn stimulate phospholipase C, leading to the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). The resulting increase in intracellular calcium levels triggers a cascade of downstream signaling events that regulate blood pressure, vascular tone, and electrolyte balance. **Pathways and Functions** The AGTR1 receptor is involved in several key signaling pathways, including: 1. **Angiotensin-activated signaling pathway**: This pathway is initiated by the binding of angiotensin II to the AGTR1 receptor, which activates a series of downstream signaling events that regulate blood pressure, vascular tone, and electrolyte balance. 2. **G protein-coupled receptor signaling pathway**: This pathway involves the activation of Gq proteins, which stimulate phospholipase C, leading to the generation of IP3 and DAG. 3. **Calcium-mediated signaling**: The activation of the AGTR1 receptor triggers an increase in intracellular calcium levels, which stimulates a cascade of downstream signaling events that regulate blood pressure, vascular tone, and electrolyte balance. 4. **Inflammatory response**: The AGTR1 receptor is involved in the regulation of inflammatory responses, and its dysregulation has been implicated in several inflammatory diseases. 5. **Cell growth and proliferation**: The AGTR1 receptor is involved in the regulation of cell growth and proliferation, and its dysregulation has been implicated in several cancer diseases. **Clinical Significance** The AGTR1 gene has been implicated in several cardiovascular and kidney diseases, including: 1. **Hypertension**: The AGTR1 receptor plays a critical role in regulating blood pressure, and its dysregulation has been implicated in the development of hypertension. 2. **Heart failure**: The AGTR1 receptor is involved in the regulation of cardiac function, and its dysregulation has been implicated in the development of heart failure. 3. **Kidney disease**: The AGTR1 receptor is involved in the regulation of renal function, and its dysregulation has been implicated in the development of kidney disease. 4. **Cardiac fibrosis**: The AGTR1 receptor is involved in the regulation of cardiac fibrosis, and its dysregulation has been implicated in the development of cardiac fibrosis. 5. **Atherosclerosis**: The AGTR1 receptor is involved in the regulation of atherosclerosis, and its dysregulation has been implicated in the development of atherosclerosis. In conclusion, the AGTR1 gene plays a critical role in the regulation of blood pressure, vascular tone, and electrolyte balance, and its dysregulation has been implicated in several cardiovascular and kidney diseases. Further research is needed to fully understand the mechanisms by which the AGTR1 receptor regulates these physiological processes and to develop effective therapeutic strategies for the treatment of AGTR1-related diseases.

Genular Protein ID: 2236217875

Symbol: AGTR1_HUMAN

Name: AT1BR

UniProtKB Accession Codes:

P30556 Q13725 Q8TBK4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 15 DrugCentral 1 EMBL 10 EMDB 2 Ensembl 8 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 2 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1378723

Title: Cloning, expression, and characterization of a gene encoding the human angiotensin II type 1A receptor.

PubMed ID: 1378723

DOI: 10.1016/s0006-291x(05)80804-6

PubMed ID: 1543512

Title: Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor.

PubMed ID: 1543512

DOI: 10.1016/0006-291x(92)91600-u

PubMed ID: 1567413

Title: Cloning and characterization of a human angiotensin II type 1 receptor.

PubMed ID: 1567413

DOI: 10.1016/s0006-291x(05)80288-8

PubMed ID: 1550596

Title: Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor.

PubMed ID: 1550596

DOI: 10.1016/0006-291x(92)90570-b

PubMed ID: 1508224

Title: Genetic analysis of the human type-1 angiotensin II receptor.

PubMed ID: 1508224

DOI: 10.1210/mend.6.7.1508224

PubMed ID: 8135787

Title: Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression.

PubMed ID: 8135787

DOI: 10.1006/bbrc.1994.1252

PubMed ID: 7792812

Title: Type 1 angiotensin II receptors of adrenal tumors.

PubMed ID: 7792812

DOI: 10.1016/0039-128x(94)00022-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8987975

Title: The active state of the AT1 angiotensin receptor is generated by angiotensin II induction.

PubMed ID: 8987975

DOI: 10.1021/bi961593m

PubMed ID: 15809376

Title: G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor.

PubMed ID: 15809376

DOI: 10.1161/01.cir.0000160867.23556.7d

PubMed ID: 15611106

Title: beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation.

PubMed ID: 15611106

DOI: 10.1074/jbc.m412924200

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 26460884

Title: G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation.

PubMed ID: 26460884

DOI: 10.1021/acs.biochem.5b00975

PubMed ID: 33713620

Title: Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system.

PubMed ID: 33713620

DOI: 10.1016/j.cell.2021.02.053

PubMed ID: 25913193

Title: Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.

PubMed ID: 25913193

DOI: 10.1016/j.cell.2015.04.011

PubMed ID: 26420482

Title: Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.

PubMed ID: 26420482

DOI: 10.1074/jbc.m115.689000

PubMed ID: 30639100

Title: Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.

PubMed ID: 30639100

DOI: 10.1016/j.cell.2018.12.006

PubMed ID: 32079768

Title: Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.

PubMed ID: 32079768

DOI: 10.1126/science.aay9813

PubMed ID: 16116425

Title: Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.

PubMed ID: 16116425

DOI: 10.1038/ng1623

Sequence Information:

  • Length: 359
  • Mass: 41061
  • Checksum: 35FC856F53E911A6
  • Sequence:
    • MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFGNSLVV IVIYFYMKLK 
TVASVFLLNL ALADLCFLLT LPLWAVYTAM EYRWPFGNYL CKIASASVSF NLYASVFLLT 
CLSIDRYLAI VHPMKSRLRR TMLVAKVTCI IIWLLAGLAS LPAIIHRNVF FIENTNITVC 
AFHYESQNST LPIGLGLTKN ILGFLFPFLI ILTSYTLIWK ALKKAYEIQK NKPRNDDIFK 
IIMAIVLFFF FSWIPHQIFT FLDVLIQLGI IRDCRIADIV DTAMPITICI AYFNNCLNPL 
FYGFLGKKFK RYFLQLLKYI PPKAKSHSNL STKMSTLSYR PSDNVSSSTK KPAPCFEVE

Genular Protein ID: 3649131496

Symbol: Q6NUP5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NUP5

Database IDs:

ARBA 10 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 IntAct 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 2 SAM 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 359
  • Mass: 41089
  • Checksum: 3F13B86F53F62CAE
  • Sequence:
    • MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFGNSLVV IVIYFYMKLK 
TVASVFLLNL ALADLCFLLT LPLWAVYTAM EYRWPFGNYL CKIASASVSF NLYASVFLLT 
CLSIDRYLAI VHPMKSRLRR TMLVAKVTCI IIWLLAGLAS LPAIIHRNVF FIENTNITVC 
AFHYESQNST LPIGLGLTKN ILGFLFPFLI ILTSYTLIWK ALKRAYEIQK NKPRNDDIFK 
IIMAIVLFFF FSWIPHQIFT FLDVLIQLGI IRDCRIADIV DTAMPITICI AYFNNCLNPL 
FYGFLGKKFK RYFLQLLKYI PPKAKSHSNL STKMSTLSYR PSDNVSSSTK KPAPCFEVE

Genular Protein ID: 3929261227

Symbol: D3DNG8_HUMAN

Name: N/A

UniProtKB Accession Codes:

D3DNG8 A0A0A0MSP9

Database IDs:

ARBA 10 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 RuleBase 2 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 394
  • Mass: 44919
  • Checksum: 9EB6A10F64A09413
  • Sequence:
    • MKKMNHKSTD SPKAPQLRGG VFDIVFATNS TQVIKMILNS STEDGIKRIQ DDCPKAGRHN 
YIFVMIPTLY SIIFVVGIFG NSLVVIVIYF YMKLKTVASV FLLNLALADL CFLLTLPLWA 
VYTAMEYRWP FGNYLCKIAS ASVSFNLYAS VFLLTCLSID RYLAIVHPMK SRLRRTMLVA 
KVTCIIIWLL AGLASLPAII HRNVFFIENT NITVCAFHYE SQNSTLPIGL GLTKNILGFL 
FPFLIILTSY TLIWKALKKA YEIQKNKPRN DDIFKIIMAI VLFFFFSWIP HQIFTFLDVL 
IQLGIIRDCR IADIVDTAMP ITICIAYFNN CLNPLFYGFL GKKFKRYFLQ LLKYIPPKAK 
SHSNLSTKMS TLSYRPSDNV SSSTKKPAPC FEVE

Genular Protein ID: 201944099

Symbol: A0A0A0MSE3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSE3

Database IDs:

ARBA 10 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 2 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 388
  • Mass: 44205
  • Checksum: 4521C804B9582A3C
  • Sequence:
    • MLTFTSECGC TTFGVFDIVF ATNSTQVIKM ILNSSTEDGI KRIQDDCPKA GRHNYIFVMI 
PTLYSIIFVV GIFGNSLVVI VIYFYMKLKT VASVFLLNLA LADLCFLLTL PLWAVYTAME 
YRWPFGNYLC KIASASVSFN LYASVFLLTC LSIDRYLAIV HPMKSRLRRT MLVAKVTCII 
IWLLAGLASL PAIIHRNVFF IENTNITVCA FHYESQNSTL PIGLGLTKNI LGFLFPFLII 
LTSYTLIWKA LKKAYEIQKN KPRNDDIFKI IMAIVLFFFF SWIPHQIFTF LDVLIQLGII 
RDCRIADIVD TAMPITICIA YFNNCLNPLF YGFLGKKFKR YFLQLLKYIP PKAKSHSNLS 
TKMSTLSYRP SDNVSSSTKK PAPCFEVE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.