Genular: Defining Cellular Identity and Function

Details for: Pax5

Gene ID: 18507

Symbol: Pax5

Ensembl ID: ENSMUSG00000014030

Description: paired box 5

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 regulates transcription of genes involved in bcr signaling
(R-MMU-8939245)
Transcriptional regulation by runx1
(R-MMU-8878171)
Adult behavior
(GO:0030534)
Anatomical structure development
(GO:0048856)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cerebral cortex development
(GO:0021987)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Dopaminergic neuron differentiation
(GO:0071542)
Embryonic cranial skeleton morphogenesis
(GO:0048701)
Lateral ventricle development
(GO:0021670)
Multicellular organism development
(GO:0007275)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Skeletal muscle cell differentiation
(GO:0035914)
Spermatogenesis
(GO:0007283)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Paired box protein Pax-5

Genular Protein ID: 11468674

Symbol: PAX5_MOUSE

Name: Paired box protein Pax-5

UniProtKB Accession Codes:

Q02650

Database IDs:

Citations:

PubMed ID: 1516825

Title: Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

PubMed ID: 1516825

DOI: 10.1101/gad.6.9.1589

PubMed ID: 1685142

Title: Pax: a murine multigene family of paired box-containing genes.

PubMed ID: 1685142

DOI: 10.1016/0888-7543(91)90151-4

PubMed ID: 9042861

Title: Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

PubMed ID: 9042861

DOI: 10.1101/gad.11.4.476

PubMed ID: 11799127

Title: The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.

PubMed ID: 11799127

DOI: 10.1074/jbc.m111763200

PubMed ID: 16546096

Title: Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

PubMed ID: 16546096

DOI: 10.1016/j.immuni.2006.01.012

Sequence Information:

Length: 391
Mass: 42231
Checksum: D703E94808DE8EC8
Sequence:

MDLEKNYPTP RTIRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV 
SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA EYKRQNPTMF AWEIRDRLLA 
ERVCDNDTVP SVSSINRIIR TKVQQPPNQP VPASSHSIVS TGSVTQVSSV STDSAGSSYS 
ISGILGITSP SADTNKRKRD EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV 
FERQHYSDIF TTTEPIKPEQ TTEYSAMASL AGGLDDMKAN LTSPTPADIG SSVPGPQSYP 
IVTGRDLAST TLPGYPPHVP PAGQGSYSAP TLTGMVPGSE FSGSPYSHPQ YSSYNDSWRF 
PNPGLLGSPY YYSPAARGAA PPAAATAYDR H

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pax5

Associated with

Other Information

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. PubMed ID: 1516825

Pax: a murine multigene family of paired box-containing genes. PubMed ID: 1685142

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. PubMed ID: 9042861