Details for: Pax8

Gene ID: 18510

Symbol: Pax8

Ensembl ID: ENSMUSG00000026976

Description: paired box 8

Associated with

  • Anatomical structure development
    (GO:0048856)
  • Animal organ morphogenesis
    (GO:0009887)
  • Cell differentiation
    (GO:0030154)
  • Cellular response to gonadotropin stimulus
    (GO:0071371)
  • Central nervous system development
    (GO:0007417)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-templated transcription
    (GO:0006351)
  • Dna binding
    (GO:0003677)
  • Epithelial cell differentiation
    (GO:0030855)
  • Inner ear morphogenesis
    (GO:0042472)
  • Kidney epithelium development
    (GO:0072073)
  • Mesonephric tubule development
    (GO:0072164)
  • Mesonephros development
    (GO:0001823)
  • Metanephric distal convoluted tubule development
    (GO:0072221)
  • Metanephric nephron tubule formation
    (GO:0072289)
  • Metanephros development
    (GO:0001656)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of apoptotic process involved in metanephric collecting duct development
    (GO:1900215)
  • Negative regulation of apoptotic process involved in metanephric nephron tubule development
    (GO:1900218)
  • Negative regulation of cardiac muscle cell apoptotic process
    (GO:0010667)
  • Negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
    (GO:0072305)
  • Negative regulation of mesenchymal cell apoptotic process involved in metanephros development
    (GO:1900212)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of branching involved in ureteric bud morphogenesis
    (GO:0090190)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
    (GO:0072108)
  • Positive regulation of metanephric dct cell differentiation
    (GO:2000594)
  • Positive regulation of thyroid hormone generation
    (GO:2000611)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Pronephric field specification
    (GO:0039003)
  • Pronephros development
    (GO:0048793)
  • Protein binding
    (GO:0005515)
  • Regulation of apoptotic process
    (GO:0042981)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of metanephric nephron tubule epithelial cell differentiation
    (GO:0072307)
  • Regulation of thyroid-stimulating hormone secretion
    (GO:2000612)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • S-shaped body morphogenesis
    (GO:0072050)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Thyroid gland development
    (GO:0030878)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Transcription regulator complex
    (GO:0005667)
  • Urogenital system development
    (GO:0001655)
  • Ventricular septum development
    (GO:0003281)

Other Information

Genular Protein ID: 3044955648

Symbol: PAX8_MOUSE

Name: Paired box protein Pax-8

UniProtKB Accession Codes:

Q00288 P97342 Q6GU20

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 11 Ensembl 1 ExpressionAtlas 1 GO 52 Gene3D 1 GeneTree 1 Genevisible 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1723950

Title: Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland.

PubMed ID: 1723950

DOI: 10.1242/dev.110.2.643

PubMed ID: 1516825

Title: Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

PubMed ID: 1516825

DOI: 10.1101/gad.6.9.1589

PubMed ID: 9205117

Title: The genomic organization of the murine Pax 8 gene and characterization of its basal promoter.

PubMed ID: 9205117

DOI: 10.1006/geno.1997.4735

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 457
  • Mass: 48793
  • Checksum: AAACD3EE54AA4488
  • Sequence:
    • MPHNSIRSGH GGLNQLGGAF VNGRPLPEVV RQRIVDLAHQ GVRPCDISRQ LRVSHGCVSK 
ILGRYYETGS IRPGVIGGSK PKVATPKVVE KIGDYKRQNP TMFAWEIRDR LLAEGVCDND 
TVPSVSSINR IIRTKVQQPF NLPMDSCVAT KSLSPGHTLI PSSAVTPPES PQSDSLGSTY 
SINGLLGIAQ PGNDNKRKMD DSDQDSCRLS IDSQSSSSGP RKHLRTDTFS QHHLEALECP 
FERQHYPEAY ASPSHTKGEQ GLYPLPLLNS ALDDGKATLT SSNTPLGRNL STHQTYPVVA 
DPHSPFAIKQ ETPELSSSSS TPSSLSSSAF LDLQQVGSGG PAGASVPPFN AFPHAASVYG 
QFTGQALLSG REMVGPTLPG YPPHIPTSGQ GSYASSAIAG MVAGSEYSGN AYSHTPYSSY 
SEAWRFPNSS LLSSPYYYSS TSRPSAPPTS ATAFDHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.