Details for: Pbx1

Gene ID: 18514

Symbol: Pbx1

Ensembl ID: ENSMUSG00000052534

Description: pre B cell leukemia homeobox 1

Associated with

Other Information

Genular Protein ID: 2503181212

Symbol: PBX1_MOUSE

Name: Pre-B-cell leukemia transcription factor 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7913464

Title: A cAMP-regulatory sequence (CRS1) of CYP17 is a cellular target for the homeodomain protein Pbx1.

PubMed ID: 7913464

DOI: 10.1016/s0021-9258(17)32223-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7791786

Title: Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

PubMed ID: 7791786

DOI: 10.1128/mcb.15.7.3786

PubMed ID: 9315626

Title: Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.

PubMed ID: 9315626

DOI: 10.1128/mcb.17.10.5679

PubMed ID: 9525891

Title: Members of the Meis1 and Pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17.

PubMed ID: 9525891

DOI: 10.1074/jbc.273.14.7941

PubMed ID: 9710595

Title: An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).

PubMed ID: 9710595

DOI: 10.1128/mcb.18.9.5109

PubMed ID: 10082572

Title: HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.

PubMed ID: 10082572

DOI: 10.1128/mcb.19.4.3051

PubMed ID: 10523646

Title: PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins.

PubMed ID: 10523646

DOI: 10.1128/mcb.19.11.7577

PubMed ID: 11279116

Title: DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex.

PubMed ID: 11279116

DOI: 10.1074/jbc.m100678200

PubMed ID: 12529389

Title: Identification of homeodomain proteins, PBX1 and PREP1, involved in the transcription of murine leukemia virus.

PubMed ID: 12529389

DOI: 10.1128/mcb.23.3.831-841.2003

PubMed ID: 19799567

Title: PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region.

PubMed ID: 19799567

DOI: 10.1042/bj20090694

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22560297

Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

PubMed ID: 22560297

DOI: 10.1016/j.devcel.2012.02.009

PubMed ID: 32190943

Title: PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.

PubMed ID: 32190943

DOI: 10.1096/fj.202000121r

PubMed ID: 10933814

Title: Conformational changes in the PBX homeodomain and C-terminal extension upon binding DNA and HOX-derived YPWM peptides(,).

PubMed ID: 10933814

DOI: 10.1021/bi0001067

PubMed ID: 12409300

Title: Lock and key binding of the HOX YPWM peptide to the PBX homeodomain.

PubMed ID: 12409300

DOI: 10.1074/jbc.m207504200

Sequence Information:

  • Length: 430
  • Mass: 46626
  • Checksum: AD3FFACBC5A9E715
  • Sequence:
  • MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 
    AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP TDPQLMRLDN MLLAEGVAGP 
    EKGGGSAAAA AAAAASGGAG SDNSVEHSDY RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM 
    NLLREQSRTR PISPKEIERM VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF 
    NKQATEILNE YFYSHLSNPY PSEEAKEELA KKCGITVSQV SNWFGNKRIR YKKNIGKFQE 
    EANIYAAKTA VTATNVSAHG SQANSPSTPN SAGSSSSFNM SNSGDLFMSV QSLNGDSYQG 
    AQVGANVQSQ VDTLRHVISQ TGGYSDGLAA SQMYSPQGIS ANGGWQDATT PSSVTSPTEG 
    PGSVHSDTSN

Genular Protein ID: 2079261156

Symbol: Q71VB4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 347
  • Mass: 38427
  • Checksum: C4A2BDDD4A410C20
  • Sequence:
  • MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 
    AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP TDPQLMRLDN MLLAEGVAGP 
    EKGGGSAAAA AAAAASGGAG SDNSVEHSDY RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM 
    NLLREQSRTR PISPKEIERM VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF 
    NKQATEILNE YFYSHLSNPY PSEEAKEELA KKCGITVSQV SNWFGNKRIR YKKNIGKFQE 
    EANIYAAKTA VTATNVSAHG SQANSPSTPN SAGGYPSPCY QPDRRIQ

Genular Protein ID: 166517580

Symbol: D9J2V6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22180614

Title: Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.

PubMed ID: 22180614

DOI: 10.4049/jimmunol.1002362

Sequence Information:

  • Length: 339
  • Mass: 37048
  • Checksum: 14256F1FF11C5814
  • Sequence:
  • MDEQPRLMHS HAGVGMAGHP GLSQHLQDGA GGTEGEGGRK QDIGDILQQI MTITDQSLDE 
    AQARKHALNC HRMKPALFNV LCEIKEKTVL SIRGAQEEEP TDPQLMRLDN MLLAEGVAGP 
    EKGGGSAAAA AAAAASGGAG SDNSVEHSDY RAKLSQIRQI YHTELEKYEQ ACNEFTTHVM 
    NLLREQSRTR PISPKEIERM VSIIHRKFSS IQMQLKQSTC EAVMILRSRF LDARRKRRNF 
    NKQATEILNE YFYSHLSNPY PSEEAKEELA KKCGITVSQV DTLRHVISQT GGYSDGLAAS 
    QMYSPQGISA NGGWQDATTP SSVTSPTEGP GSVHSDTSN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.