Details for: Pcsk1
Associated with
Other Information
Genular Protein ID: 1362027499
Symbol: NEC1_MOUSE
Name: Neuroendocrine convertase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1862107
Title: Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.
PubMed ID: 1862107
PubMed ID: 1657897
Title: Cloning and functional expression of a novel endoprotease involved in prohormone processing at dibasic sites.
PubMed ID: 1657897
PubMed ID: 2017186
Title: Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
PubMed ID: 2017186
DOI: 10.1210/mend-5-1-111
PubMed ID: 8449925
Title: Purification and characterization of the prohormone convertase PC1(PC3).
PubMed ID: 8449925
PubMed ID: 2169760
Title: cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.
PubMed ID: 2169760
PubMed ID: 2264933
PubMed ID: 16384863
Title: Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3.
PubMed ID: 16384863
DOI: 10.1210/en.2005-1373
PubMed ID: 12095256
Title: Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus.
PubMed ID: 12095256
Sequence Information:
- Length: 753
- Mass: 84174
- Checksum: 04239C7B6385382E
- Sequence:
MEQRGWTLQC TAFAFFCVWC ALNSVKAKRQ FVNEWAAEIP GGQEAASAIA EELGYDLLGQ IGSLENHYLF KHKSHPRRSR RSALHITKRL SDDDRVTWAE QQYEKERSKR SVQKDSALDL FNDPMWNQQW YLQDTRMTAA LPKLDLHVIP VWEKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DLTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ASNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRN VPEKKECVVK DNNFEPRALK ANGEVIVEIP TRACEGQENA IKSLEHVQFE ATIEYSRRGD LHVTLTSAVG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPVGTWTLK ITDMSGRMQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVNVVEKR PTQKSLNGNL LVPKNSSSSN VEGRRDEQVQ GTPSKAMLRL LQSAFSKNAL SKQSPKKSPS AKLSIPYESF YEALEKLNKP SKLEGSEDSL YSDYVDVFYN TKPYKHRDDR LLQALMDILN EEN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.