Genular: Defining Cellular Identity and Function

Details for: Pde1a

Gene ID: 18573

Symbol: Pde1a

Ensembl ID: ENSMUSG00000059173

Description: phosphodiesterase 1A, calmodulin-dependent

Associated with

Ca-dependent events
(R-MMU-111996)
Calmodulin induced events
(R-MMU-111933)
Cam-pde 1 activation
(R-MMU-111957)
Cam pathway
(R-MMU-111997)
Cgmp effects
(R-MMU-418457)
Dag and ip3 signaling
(R-MMU-1489509)
G-protein mediated events
(R-MMU-112040)
G alpha (i) signalling events
(R-MMU-418594)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Hemostasis
(R-MMU-109582)
Intracellular signaling by second messengers
(R-MMU-9006925)
Nitric oxide stimulates guanylate cyclase
(R-MMU-392154)
Opioid signalling
(R-MMU-111885)
Platelet homeostasis
(R-MMU-418346)
Plc beta mediated events
(R-MMU-112043)
Signaling by gpcr
(R-MMU-372790)
3',5'-cyclic-amp phosphodiesterase activity
(GO:0004115)
3',5'-cyclic-gmp phosphodiesterase activity
(GO:0047555)
3',5'-cyclic-nucleotide phosphodiesterase activity
(GO:0004114)
Calmodulin-activated 3',5'-cyclic-gmp phosphodiesterase activity
(GO:0048101)
Calmodulin-activated dual specificity 3',5'-cyclic-gmp, 3',5'-cyclic-amp phosphodiesterase activity
(GO:0004117)
Calmodulin binding
(GO:0005516)
Camp-mediated signaling
(GO:0019933)
Cell projection
(GO:0042995)
Cgmp catabolic process
(GO:0046069)
Cilium
(GO:0005929)
Hydrolase activity
(GO:0016787)
Metal ion binding
(GO:0046872)
Motile cilium
(GO:0031514)
Neuronal cell body
(GO:0043025)
Phosphoric diester hydrolase activity
(GO:0008081)
Regulation of smooth muscle cell apoptotic process
(GO:0034391)
Regulation of smooth muscle cell proliferation
(GO:0048660)
Signal transduction
(GO:0007165)
Sperm flagellum
(GO:0036126)

Other Information

Proteins

61 kDa Cam-PDE

Genular Protein ID: 184733359

Symbol: PDE1A_MOUSE

Name: 61 kDa Cam-PDE

UniProtKB Accession Codes:

Q61481 E9Q6V1 O35388 Q5I7S8 Q8BRR9 Q9JLL9

Database IDs:

Citations:

PubMed ID: 15901640

Title: Identification of a new variant of PDE1A calmodulin-stimulated cyclic nucleotide phosphodiesterase expressed in mouse sperm.

PubMed ID: 15901640

DOI: 10.1095/biolreprod.104.039180

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 545
Mass: 62347
Checksum: 5B794C8DE8456917
Sequence:

MGSTDTDIEE LENATYKYLI GEQTEKMWQR LKGILRCLVK QLEKGDVNVV DLKKNIEYAA 
SVLEAVYIDE TRRLLDTEDE LSDIQTDSVP SEVRDWLAST FTRKMGMMKK KPEEKPKFRS 
IVHAVQAGIF VERMYRKNYH MVGLTYPAAV IVTLKEVDKW SFDVFALNEA SGEHSLKFMI 
YELFTRYDLI NRFKIPVSCL IAFAEALEVG YSKHKNPYHN LVHAADVTQT VHYIMLHTGI 
MHWLTELEIL AMVFAAAIHD YEHTGTTNNF HIQTRSDVAI LYNDRSVLEN HHVSAAYRLM 
QEEEMNILVN LSKDDWRDLR NLVIEMVLAT DMSGHFQQIK NIRNSLQQPE GIDRAKTMSL 
ILHAADISHP AKTWKLHYRW TMALMEEFFL QGDKEAELGL PFSPLCDRKS TMVAQSQIGF 
IDFIVEPTFS LLTDSTEKIV IPLIEEASKS QSSNYGASSS STMIGFHVAD SLRRSNTKGS 
VCDGSYAPDY SLSAVDLKSF KNNLVDIIQQ NKERWKELAA QGELDLHKNS EELGNTEEKH 
ADTRP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pde1a

Associated with

Other Information

Identification of a new variant of PDE1A calmodulin-stimulated cyclic nucleotide phosphodiesterase expressed in mouse sperm. PubMed ID: 15901640

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303