Details for: AGTR2

Gene ID: 186

Symbol: AGTR2

Ensembl ID: ENSG00000180772

Description: angiotensin II receptor type 2

Associated with

  • Class a/1 (rhodopsin-like receptors)
    (R-HSA-373076)
  • G alpha (i) signalling events
    (R-HSA-418594)
  • Gpcr downstream signalling
    (R-HSA-388396)
  • Gpcr ligand binding
    (R-HSA-500792)
  • Peptide ligand-binding receptors
    (R-HSA-375276)
  • Signaling by gpcr
    (R-HSA-372790)
  • Signal transduction
    (R-HSA-162582)
  • Angiotensin-activated signaling pathway
    (GO:0038166)
  • Angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure
    (GO:0002033)
  • Angiotensin type ii receptor activity
    (GO:0004945)
  • Blood vessel remodeling
    (GO:0001974)
  • Brain development
    (GO:0007420)
  • Brain renin-angiotensin system
    (GO:0002035)
  • Cell surface receptor signaling pathway
    (GO:0007166)
  • Exploration behavior
    (GO:0035640)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • G protein-coupled receptor signaling pathway coupled to cgmp nucleotide second messenger
    (GO:0007199)
  • Inflammatory response
    (GO:0006954)
  • Negative regulation of blood vessel endothelial cell migration
    (GO:0043537)
  • Negative regulation of cell growth
    (GO:0030308)
  • Negative regulation of heart rate
    (GO:0010459)
  • Negative regulation of neurotrophin trk receptor signaling pathway
    (GO:0051387)
  • Neuron apoptotic process
    (GO:0051402)
  • Nitric oxide-cgmp-mediated signaling
    (GO:0038060)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of branching involved in ureteric bud morphogenesis
    (GO:0090190)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of extrinsic apoptotic signaling pathway
    (GO:2001238)
  • Positive regulation of metanephric glomerulus development
    (GO:0072300)
  • Protein binding
    (GO:0005515)
  • Receptor antagonist activity
    (GO:0048019)
  • Regulation of blood pressure
    (GO:0008217)
  • Regulation of metanephros size
    (GO:0035566)
  • Regulation of systemic arterial blood pressure by circulatory renin-angiotensin
    (GO:0001991)
  • Vasodilation
    (GO:0042311)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 8.4380
    Cell Significance Index: 63.1700
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 0.4387
    Cell Significance Index: 2.5900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2307
    Cell Significance Index: 2.9600
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.1391
    Cell Significance Index: 1.5600
  • Cell Name: muscle precursor cell (CL0000680)
    Fold Change: 0.1273
    Cell Significance Index: 0.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0694
    Cell Significance Index: 52.5400
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.0042
    Cell Significance Index: 0.0400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0011
    Cell Significance Index: -0.0500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0012
    Cell Significance Index: -0.0400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0017
    Cell Significance Index: -0.9200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0024
    Cell Significance Index: -0.1000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0027
    Cell Significance Index: -0.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0032
    Cell Significance Index: -1.8000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0035
    Cell Significance Index: -0.1200
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0052
    Cell Significance Index: -0.0800
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0063
    Cell Significance Index: -0.0700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0063
    Cell Significance Index: -0.1100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0072
    Cell Significance Index: -0.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0083
    Cell Significance Index: -1.6600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0107
    Cell Significance Index: -1.8300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0119
    Cell Significance Index: -1.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0145
    Cell Significance Index: -1.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0161
    Cell Significance Index: -1.8500
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0224
    Cell Significance Index: -0.1900
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0233
    Cell Significance Index: -0.2800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0233
    Cell Significance Index: -1.7900
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0288
    Cell Significance Index: -0.4000
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0306
    Cell Significance Index: -0.4200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0349
    Cell Significance Index: -1.2800
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.0351
    Cell Significance Index: -0.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0371
    Cell Significance Index: -2.0800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0409
    Cell Significance Index: -1.0200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0412
    Cell Significance Index: -2.1400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0440
    Cell Significance Index: -1.5300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0470
    Cell Significance Index: -1.5400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0471
    Cell Significance Index: -1.2600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0521
    Cell Significance Index: -1.6600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0529
    Cell Significance Index: -1.3900
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0576
    Cell Significance Index: -0.7500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0637
    Cell Significance Index: -1.5900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0708
    Cell Significance Index: -2.0300
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.0716
    Cell Significance Index: -0.7500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0736
    Cell Significance Index: -2.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0761
    Cell Significance Index: -1.6200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0762
    Cell Significance Index: -1.7600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0777
    Cell Significance Index: -1.9800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0787
    Cell Significance Index: -1.5700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0794
    Cell Significance Index: -2.1200
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.0803
    Cell Significance Index: -0.8200
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.0814
    Cell Significance Index: -0.8400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0827
    Cell Significance Index: -1.6600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0846
    Cell Significance Index: -0.9200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0847
    Cell Significance Index: -0.7200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0857
    Cell Significance Index: -2.1400
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0867
    Cell Significance Index: -1.1100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0903
    Cell Significance Index: -1.8900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0951
    Cell Significance Index: -1.8600
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0962
    Cell Significance Index: -1.1700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1031
    Cell Significance Index: -1.4800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1033
    Cell Significance Index: -0.8300
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.1033
    Cell Significance Index: -1.2200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1089
    Cell Significance Index: -1.5600
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1105
    Cell Significance Index: -1.7900
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.1128
    Cell Significance Index: -1.4200
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.1136
    Cell Significance Index: -0.9200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1165
    Cell Significance Index: -1.3400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1209
    Cell Significance Index: -1.1700
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.1223
    Cell Significance Index: -0.9900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1245
    Cell Significance Index: -1.7900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1246
    Cell Significance Index: -1.8400
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.1249
    Cell Significance Index: -1.4400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1261
    Cell Significance Index: -1.3300
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1281
    Cell Significance Index: -1.3600
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.1289
    Cell Significance Index: -1.1700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1291
    Cell Significance Index: -1.6300
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.1293
    Cell Significance Index: -2.2100
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1293
    Cell Significance Index: -1.5200
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.1294
    Cell Significance Index: -1.4200
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.1294
    Cell Significance Index: -1.7600
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1296
    Cell Significance Index: -1.0700
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.1302
    Cell Significance Index: -1.6100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.1303
    Cell Significance Index: -2.0900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.1312
    Cell Significance Index: -1.8400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1315
    Cell Significance Index: -1.6400
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1316
    Cell Significance Index: -1.6000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1319
    Cell Significance Index: -2.0400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.1331
    Cell Significance Index: -1.2500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1331
    Cell Significance Index: -2.2600
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.1333
    Cell Significance Index: -1.4100
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.1339
    Cell Significance Index: -1.6300
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1349
    Cell Significance Index: -1.6900
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.1357
    Cell Significance Index: -1.4000
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.1362
    Cell Significance Index: -1.6100
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1377
    Cell Significance Index: -1.7200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1381
    Cell Significance Index: -2.7300
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.1394
    Cell Significance Index: -1.8200
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.1398
    Cell Significance Index: -1.8400
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.1425
    Cell Significance Index: -1.6600
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.1425
    Cell Significance Index: -1.8600
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1428
    Cell Significance Index: -1.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Receptor function:** AGTR2 is a G protein-coupled receptor (GPCR) that binds to angiotensin II, a peptide hormone produced in the kidneys, to activate downstream signaling pathways. 2. **Expression:** AGTR2 is expressed in various tissues, including the brain, kidneys, heart, blood vessels, and immune cells, such as microglia, T cells, and dendritic cells. 3. **Signaling pathways:** AGTR2 activates multiple signaling pathways, including the angiotensin-activated signaling pathway, Gαi signaling events, and nitric oxide-mediated signal transduction, which regulate blood pressure, inflammation, and cell growth. **Pathways and Functions:** 1. **Angiotensin-activated signaling pathway:** AGTR2 activation leads to the phosphorylation and activation of downstream kinases, which in turn modulate blood pressure, fluid balance, and electrolyte homeostasis. 2. **Vasodilation:** AGTR2 activation promotes vasodilation, which helps to regulate systemic arterial blood pressure and maintain cardiovascular homeostasis. 3. **Inflammation regulation:** AGTR2 signaling pathways also modulate inflammatory responses, including the regulation of immune cell activation and cytokine production. 4. **Cell growth and apoptosis:** AGTR2 activation can inhibit cell growth and promote apoptosis in certain cell types, including neurons and endothelial cells. 5. **Renal function:** AGTR2 plays a critical role in regulating renal function, including the modulation of blood pressure, sodium excretion, and kidney development. **Clinical Significance:** The AGTR2 gene has been implicated in various diseases, including: 1. **Hypertension:** AGTR2 dysfunction has been linked to hypertension, a major risk factor for cardiovascular disease and kidney disease. 2. **Kidney disease:** AGTR2 plays a critical role in regulating renal function, and its dysfunction can contribute to kidney disease, including chronic kidney disease and end-stage renal disease. 3. **Cardiovascular disease:** AGTR2 activation can promote cardiovascular disease, including atherosclerosis, heart failure, and cardiac arrhythmias. 4. **Neurological disorders:** AGTR2 signaling pathways have been implicated in neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. In conclusion, the AGTR2 gene is a critical component of the renin-angiotensin system, and its dysregulation can contribute to various diseases. Further research is needed to fully understand the complex relationships between AGTR2 and its downstream signaling pathways, as well as its role in maintaining cardiovascular and renal homeostasis.

Genular Protein ID: 2311086221

Symbol: AGTR2_HUMAN

Name: N/A

UniProtKB Accession Codes:

P50052 B2R9V1 Q13016 Q6FGY7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 7 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EMBL 15 Ensembl 2 GO 27 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7733925

Title: The sequence and genomic organization of the human type 2 angiotensin II receptor.

PubMed ID: 7733925

DOI: 10.1006/bbrc.1995.1537

PubMed ID: 7790004

Title: Assignment of the human angiotensin II type 2 receptor gene (AGTR2) to chromosome Xq22-q23 by fluorescence in situ hybridization.

PubMed ID: 7790004

DOI: 10.1016/0888-7543(95)80072-t

PubMed ID: 7945336

Title: Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.

PubMed ID: 7945336

DOI: 10.1006/bbrc.1994.2402

PubMed ID: 8185599

Title: Molecular cloning and expression of the gene encoding human angiotensin II type 2 receptor.

PubMed ID: 8185599

DOI: 10.1006/bbrc.1994.1613

PubMed ID: 7999093

Title: Molecular cloning of the human angiotensin II type 2 receptor cDNA.

PubMed ID: 7999093

DOI: 10.1006/bbrc.1994.2714

PubMed ID: 7719706

Title: Molecular characterization and chromosome localization of a human angiotensin II AT2 receptor gene highly expressed in fetal tissues.

PubMed ID: 7719706

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12089445

Title: AGTR2 mutations in X-linked mental retardation.

PubMed ID: 12089445

DOI: 10.1126/science.1072191

PubMed ID: 15123706

Title: Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP.

PubMed ID: 15123706

DOI: 10.1074/jbc.m403880200

PubMed ID: 23871722

Title: XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing.

PubMed ID: 23871722

DOI: 10.1016/j.ajhg.2013.06.013

PubMed ID: 28379944

Title: Structural basis for selectivity and diversity in angiotensin II receptors.

PubMed ID: 28379944

DOI: 10.1038/nature22035

PubMed ID: 29967536

Title: Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog.

PubMed ID: 29967536

DOI: 10.1038/s41594-018-0079-8

PubMed ID: 32669569

Title: The discovery of a new antibody for BRIL-fused GPCR structure determination.

PubMed ID: 32669569

DOI: 10.1038/s41598-020-68355-x

PubMed ID: 31899086

Title: The crystal structure of angiotensin II type 2 receptor with endogenous peptide hormone.

PubMed ID: 31899086

DOI: 10.1016/j.str.2019.12.003

Sequence Information:

  • Length: 363
  • Mass: 41184
  • Checksum: FDD7D4E6F9B43E60
  • Sequence:
    • MKGNSTLATT SKNITSGLHF GLVNISGNNE STLNCSQKPS DKHLDAIPIL YYIIFVIGFL 
VNIVVVTLFC CQKGPKKVSS IYIFNLAVAD LLLLATLPLW ATYYSYRYDW LFGPVMCKVF 
GSFLTLNMFA SIFFITCMSV DRYQSVIYPF LSQRRNPWQA SYIVPLVWCM ACLSSLPTFY 
FRDVRTIEYL GVNACIMAFP PEKYAQWSAG IALMKNILGF IIPLIFIATC YFGIRKHLLK 
TNSYGKNRIT RDQVLKMAAA VVLAFIICWL PFHVLTFLDA LAWMGVINSC EVIAVIDLAL 
PFAILLGFTN SCVNPFLYCF VGNRFQQKLR SVFRVPITWL QGKRESMSCR KSSSLREMET 
FVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.