Details for: Padi4

Gene ID: 18602

Symbol: Padi4

Ensembl ID: ENSMUSG00000025330

Description: peptidyl arginine deiminase, type IV

Associated with

Other Information

Genular Protein ID: 453519477

Symbol: PADI4_MOUSE

Name: Protein-arginine deiminase type-4

UniProtKB Accession Codes:

Q9Z183 A2AMU3 Q75WC7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 22 ChEMBL 1 DNASU 1 EC 1 EMBL 3 EPD 1 Ensembl 1 GO 17 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 7 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIRSF 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 3 SMR 1 STRING 1 SUPFAM 3 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10092850

Title: Molecular cloning of cDNAs of mouse peptidylarginine deiminase type I, type III and type IV, and the expression pattern of type I in mouse.

PubMed ID: 10092850

DOI: 10.1046/j.1432-1327.1999.00083.x

PubMed ID: 15087120

Title: Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6.

PubMed ID: 15087120

DOI: 10.1016/j.gene.2003.12.038

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15339660

Title: Histone deimination antagonizes arginine methylation.

PubMed ID: 15339660

DOI: 10.1016/j.cell.2004.08.020

PubMed ID: 20733033

Title: PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.

PubMed ID: 20733033

DOI: 10.1084/jem.20100239

PubMed ID: 23650392

Title: Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice.

PubMed ID: 23650392

DOI: 10.1073/pnas.1301059110

PubMed ID: 24463520

Title: Citrullination regulates pluripotency and histone H1 binding to chromatin.

PubMed ID: 24463520

DOI: 10.1038/nature12942

PubMed ID: 32528174

Title: DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.

PubMed ID: 32528174

DOI: 10.1038/s41586-020-2394-6

Sequence Information:

  • Length: 666
  • Mass: 74415
  • Checksum: F25B7A7B69285C32
  • Sequence:
    • MAQGAVIHVA PEQPTHAVCV VGTATPLDVR GSAPKGYTTF GITASPGVIV DVIHGPPVKK 
STMGASKWPL DPELEVTLQV KAASSRTDDE KVRVSYYGPK TSPVQALIYI TGVELSLSAD 
VTRTGRVKPA QAGKDQSTWT WGPGGRGAIL LVNCDKEDPQ ASGMDFEDDK ILDNKDLQDM 
SPMTLSTKTP KDFFEKYQLV LEVPKAKMNR VRVFRATRGK LPSRYKVALG PQQFSYCLEL 
PGGQHSTDFY VEGLAFPDAD FKGLIPLTIS LLDKSNPELP EALVFQDSVT FRVAPWIMTP 
NTQPPQEVYV CRVSDNEDFL KSLATLTKKA KCKLTVCPEE ENIDDQWMQD EMEIGYIQAP 
HKTLPVVFDS PRDRGLKDFP VKRVMGPNFG YVTRKLYMSE LTGLDAFGNL EVSPPVTVRG 
KEYPLGRILI GNSGYSSSES RDMHQALQDF LSAQQVQAPV RLFSDWLFVG HVDEFLSFVP 
ARDKQGFRLL LSSPRACYQL FQELQSQGHG EATLFEGLKR KRQTINEILS NKKLRDQNAY 
VESCIDWNRA VLKRELGLAE GDIIDIPQLF KLAGNSRGNS KAQAFFPNMV NMLVLGKYLG 
IPKPFGPIID GHCCLEEEVR SHLEPLGLHC TFINDFYTYH VYNGEVHCGT NVRRKPFTFK 
WWHMVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.