Details for: Enpp1
Associated with
Other Information
Genular Protein ID: 2177723252
Symbol: ENPP1_MOUSE
Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3104326
Title: Plasma cell membrane glycoprotein PC-1. Primary structure deduced from cDNA clones.
PubMed ID: 3104326
PubMed ID: 1647027
Title: Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1.
PubMed ID: 1647027
PubMed ID: 12121276
Title: Structural basis of allotypes of ecto-nucleotide pyrophosphatase/phosphodiesterase (plasma cell membrane glycoprotein PC-1) in the mouse and rat, and analysis of allele-specific xenogeneic antibodies.
PubMed ID: 12121276
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 8223581
Title: Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase).
PubMed ID: 8223581
PubMed ID: 3001713
Title: Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression.
PubMed ID: 3001713
PubMed ID: 3917281
Title: The murine plasma cell antigen PC-1: purification and partial amino acid sequence.
PubMed ID: 3917281
PubMed ID: 2211644
Title: Plasma cell membrane glycoprotein PC-1. cDNA cloning of the human molecule, amino acid sequence, and chromosomal location.
PubMed ID: 2211644
PubMed ID: 9662402
Title: Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine.
PubMed ID: 9662402
DOI: 10.1038/956
PubMed ID: 10352096
Title: Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells.
PubMed ID: 10352096
PubMed ID: 11004006
Title: Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1.
PubMed ID: 11004006
PubMed ID: 12082181
Title: Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization.
PubMed ID: 12082181
PubMed ID: 11027689
Title: Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases.
PubMed ID: 11027689
PubMed ID: 11598187
Title: Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis.
PubMed ID: 11598187
PubMed ID: 15075217
Title: Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1.
PubMed ID: 15075217
PubMed ID: 19419305
Title: New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification.
PubMed ID: 19419305
DOI: 10.1359/jbmr.090417
PubMed ID: 19656770
Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.
PubMed ID: 19656770
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 22510396
Title: Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.
PubMed ID: 22510396
PubMed ID: 25260930
Title: Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(-/-) mice.
PubMed ID: 25260930
PubMed ID: 25344812
Title: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
PubMed ID: 25344812
PubMed ID: 25479107
Title: Spontaneous asj-2J mutant mouse as a model for generalized arterial calcification of infancy: a large deletion/insertion mutation in the Enpp1 gene.
PubMed ID: 25479107
PubMed ID: 26910915
Title: Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1asj-2J mice.
PubMed ID: 26910915
PubMed ID: 30111653
Title: Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling.
PubMed ID: 30111653
DOI: 10.1242/dev.164830
PubMed ID: 35147247
Title: The Mineralization Regulator ANKH Mediates Cellular Efflux of ATP, Not Pyrophosphate.
PubMed ID: 35147247
DOI: 10.1002/jbmr.4528
PubMed ID: 23027977
Title: Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
PubMed ID: 23027977
PubMed ID: 23041369
Title: Structure of NPP1, an ectonucleotide pyrophosphatase/ phosphodiesterase involved in tissue calcification.
PubMed ID: 23041369
PubMed ID: 30356045
Title: Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
PubMed ID: 30356045
Sequence Information:
- Length: 906
- Mass: 103176
- Checksum: 068D45B0ED0F224D
- Sequence:
MERDGDQAGH GPRHGSAGNG RELESPAAAS LLAPMDLGEE PLEKAERARP AKDPNTYKVL SLVLSVCVLT TILGCIFGLK PSCAKEVKSC KGRCFERTFS NCRCDAACVS LGNCCLDFQE TCVEPTHIWT CNKFRCGEKR LSRFVCSCAD DCKTHNDCCI NYSSVCQDKK SWVEETCESI DTPECPAEFE SPPTLLFSLD GFRAEYLHTW GGLLPVISKL KNCGTYTKNM RPMYPTKTFP NHYSIVTGLY PESHGIIDNK MYDPKMNASF SLKSKEKFNP LWYKGQPIWV TANHQEVKSG TYFWPGSDVE IDGILPDIYK VYNGSVPFEE RILAVLEWLQ LPSHERPHFY TLYLEEPDSS GHSHGPVSSE VIKALQKVDR LVGMLMDGLK DLGLDKCLNL ILISDHGMEQ GSCKKYVYLN KYLGDVNNVK VVYGPAARLR PTDVPETYYS FNYEALAKNL SCREPNQHFR PYLKPFLPKR LHFAKSDRIE PLTFYLDPQW QLALNPSERK YCGSGFHGSD NLFSNMQALF IGYGPAFKHG AEVDSFENIE VYNLMCDLLG LIPAPNNGSH GSLNHLLKKP IYNPSHPKEE GFLSQCPIKS TSNDLGCTCD PWIVPIKDFE KQLNLTTEDV DDIYHMTVPY GRPRILLKQH HVCLLQQQQF LTGYSLDLLM PLWASYTFLR NDQFSRDDFS NCLYQDLRIP LSPVHKCSYY KSNSKLSYGF LTPPRLNRVS NHIYSEALLT SNIVPMYQSF QVIWHYLHDT LLQRYAHERN GINVVSGPVF DFDYDGRYDS LEILKQNSRV IRSQEILIPT HFFIVLTSCK QLSETPLECS ALESSAYILP HRPDNIESCT HGKRESSWVE ELLTLHRARV TDVELITGLS FYQDRQESVS ELLRLKTHLP IFSQED
Genular Protein ID: 1121875556
Symbol: A0A0R4J1Q7_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 906
- Mass: 103125
- Checksum: 1FA071071E4B9C50
- Sequence:
MERDGDQAGH GPRHGSAGNG RELESPAAAS LLAPMDLGEE PLEKAERARP AKDPNTYKVL SLVLSVCVLT TILGCIFGLK PSCAKEVKSC KGRCFERTFS NCRCDAACVS LGNCCLDFQE TCVEPTHIWT CNKFRCGEKR LSRFVCSCAD DCKTHNDCCI NYSSVCQDKK SWVEETCESI DTPECPAEFE SPPTLLFSLD GFRAEYLHTW GGLLPVISKL KNCGTYTKNM RPMYPTKTFP NHYSIVTGLY PESHGIIDNK MYDPKMNASF SLKSKEKFNP LWYKGQPIWV TANHQEVKSG TYFWPGSDVE IDGILPDIYK VYNGSVPFEE RILAVLEWLQ LPSHERPHFY TLYLEEPDSS GHSHGPVSSE VIKALQKVDR LVGMLMDGLK DLGLDKCLNL ILISDHGMEQ GSCKKYVYLN KYLGDVNNVK VVYGPAARLR PTDVPETYYS FNYEALAKNL SCREPNQHFR PYLKPFLPKR LHFAKSDRIE PLTFYLDPQW QLALNPSERK YCGSGFHGSD NLFSNMQALF IGYGPAFKHG AEVDSFENIE VYNLMCDLLG LIPAPNNGSH GSLNHLLKKP IYNPSHPKEE GFLSQCPIKS TSNDLGCTCD PWIVPIKDFE KQLNLTTEDV DDIYHMTVPY GRPRILLKQH RVCLLQQQQF LTGYSLDLLM PLWASYTFLS NDQFSRDDFS NCLYQDLRIP LSPVHKCSYY KSNSKLSYGF LTPPRLNRVS NHIYSEALLT SNIVPMYQSF QVIWHYLHDT LLQRYAHERN GINVVSGPVF DFDYDGRYDS LEILKQNSRV IRSQEILIPT HFFIVLTSCK QLSETPLECS ALESSAYILP HRPDNIESCT HGKRESSWVE ELLTLHRARV TDVELITGLS FYQDRQESVS ELLRLKTHLP IFSQED
Genular Protein ID: 1464808844
Symbol: G3X9S2_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 905
- Mass: 103026
- Checksum: E243DA170C212A3C
- Sequence:
MERDGDQAGH GPRHGSAGNG RELESPAAAS LLAPMDLGEE PLEKAERARP AKDPNTYKVL SLVLSVCVLT TILGCIFGLK PSCAKEVKSC KGRCFERTFS NCRCDAACVS LGNCCLDFQE TCVEPTHIWT CNKFRCGEKR LSRFVCSCAD DCKTHNDCCI NYSSVCQDKK SWVEETCESI DTPECPAEFE SPPTLLFSLD GFRAEYLHTW GGLLPVISKL KNCGTYTKNM RPMYPTKTFP NHYSIVTGLY PESHGIIDNK MYDPKMNASF SLKSKEKFNP LWYKGQPIWV TANHQEVKSG TYFWPGSDVE IDGILPDIYK VYNGSVPFEE RILAVLEWLQ LPSHERPHFY TLYLEEPDSS GHSHGPVSSE VIKALQKVDR LVGMLMDGLK DLGLDKCLNL ILISDHGMEQ GSCKKYVYLN KYLGDVNNVK VVYGPAARLR PTDVPETYYS FNYEALAKNL SCREPNQHFR PYLKPFLPKR LHFAKSDRIE PLTFYLDPQW QLALNPSERK YCGSGFHGSD NLFSNMQALF IGYGPAFKHG AEVDSFENIE VYNLMCDLLG LIPAPNNGSH GSLNHLLKKP IYNPSHPKEE GFLSQCPIKS TSNDLGCTCD PWIVPIKDFE KQLNLTTEDD DIYHMTVPYG RPRILLKQHR VCLLQQQQFL TGYSLDLLMP LWASYTFLSN DQFSRDDFSN CLYQDLRIPL SPVHKCSYYK SNSKLSYGFL TPPRLNRVSN HIYSEALLTS NIVPMYQSFQ VIWHYLHDTL LQRYAHERNG INVVSGPVFD FDYDGRYDSL EILKQNSRVI RSQEILIPTH FFIVLTSCKQ LSETPLECSA LESSAYILPH RPDNIESCTH GKRESSWVEE LLTLHRARVT DVELITGLSF YQDRQESVSE LLRLKTHLPI FSQED
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.