Genular: Defining Cellular Identity and Function

Details for: Pea15a

Gene ID: 18611

Symbol: Pea15a

Ensembl ID: ENSMUSG00000013698

Description: proliferation and apoptosis adaptor protein 15A

Associated with

Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Raf-independent mapk1/3 activation
(R-MMU-112409)
Raf/map kinase cascade
(R-MMU-5673001)
Signal transduction
(R-MMU-162582)
Apoptotic process
(GO:0006915)
Carbohydrate transport
(GO:0008643)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Intracellular membrane-bounded organelle
(GO:0043231)
Intracellular signal transduction
(GO:0035556)
Mapk cascade
(GO:0000165)
Microtubule associated complex
(GO:0005875)
Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
(GO:1902042)
Negative regulation of glucose import
(GO:0046325)
Nucleoplasm
(GO:0005654)
Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
(GO:1902043)
Protein kinase c binding
(GO:0005080)
Regulation of apoptotic process
(GO:0042981)

Other Information

Proteins

Astrocytic phosphoprotein PEA-15

Genular Protein ID: 1285723739

Symbol: PEA15_MOUSE

Name: Astrocytic phosphoprotein PEA-15

UniProtKB Accession Codes:

Q62048 Q3U5N7

Database IDs:

Citations:

PubMed ID: 8662970

Title: The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human.

PubMed ID: 8662970

DOI: 10.1074/jbc.271.25.14800

PubMed ID: 11210189

Title: Identification of a novel, alternatively spliced isoform and single nucleotide polymorphisms in the murine Pea-15 gene.

PubMed ID: 11210189

DOI: 10.1007/s003350010243

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10588860

Title: The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis.

PubMed ID: 10588860

DOI: 10.1006/dbio.1999.9510

PubMed ID: 10926929

Title: Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them.

PubMed ID: 10926929

DOI: 10.1074/jbc.m003329200

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 130
Mass: 15054
Checksum: 780F93A40B2834A8
Sequence:

MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL 
SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEEELDTKLT RIPSAKKYKD IIRQPSEEEI 
IKLAPPPKKA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pea15a

Associated with

Other Information

The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human. PubMed ID: 8662970

Identification of a novel, alternatively spliced isoform and single nucleotide polymorphisms in the murine Pea-15 gene. PubMed ID: 11210189

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis. PubMed ID: 10588860

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them. PubMed ID: 10926929

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079