Genular: Defining Cellular Identity and Function

Details for: Pemt

Gene ID: 18618

Symbol: Pemt

Ensembl ID: ENSMUSG00000000301

Description: phosphatidylethanolamine N-methyltransferase

Associated with

Glycerophospholipid biosynthesis
(R-MMU-1483206)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Phospholipid metabolism
(R-MMU-1483257)
Synthesis of pc
(R-MMU-1483191)
Blastocyst hatching
(GO:0001835)
Brush border membrane
(GO:0031526)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Glycerophospholipid metabolic process
(GO:0006650)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Methylation
(GO:0032259)
Methyltransferase activity
(GO:0008168)
Mitochondrial envelope
(GO:0005740)
Mitochondrion
(GO:0005739)
Negative regulation of cell population proliferation
(GO:0008285)
Phosphatidyl-n-dimethylethanolamine n-methyltransferase activity
(GO:0080101)
Phosphatidyl-n-methylethanolamine n-methyltransferase activity
(GO:0000773)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phosphatidylethanolamine binding
(GO:0008429)
Phosphatidylethanolamine n-methyltransferase activity
(GO:0004608)
Phospholipid biosynthetic process
(GO:0008654)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of lipoprotein metabolic process
(GO:0050747)
Response to vitamin
(GO:0033273)
Response to xenobiotic stimulus
(GO:0009410)
S-adenosylhomocysteine metabolic process
(GO:0046498)
S-adenosylmethionine-dependent methyltransferase activity
(GO:0008757)
S-adenosylmethionine metabolic process
(GO:0046500)
Sarcolemma
(GO:0042383)
Sphingomyelin biosynthetic process
(GO:0006686)
Transferase activity
(GO:0016740)

Other Information

Proteins

PEMT_MOUSE

Genular Protein ID: 1457116114

Symbol: PEMT_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q61907 Q3UZN8 Q7TNW6 Q8R0I1

Database IDs:

Citations:

PubMed ID: 8978486

Title: Characterization of the murine phosphatidylethanolamine N-methyltransferase-2 gene.

PubMed ID: 8978486

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9371769

Title: Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase.

PubMed ID: 9371769

DOI: 10.1073/pnas.94.24.12880

PubMed ID: 9765216

Title: Biochemical and evolutionary significance of phospholipid methylation.

PubMed ID: 9765216

DOI: 10.1074/jbc.273.42.27043

PubMed ID: 12482759

Title: Plasma homocysteine is regulated by phospholipid methylation.

PubMed ID: 12482759

DOI: 10.1074/jbc.m212194200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 199
Mass: 22579
Checksum: 0F96C1CC3B483DC6
Sequence:

MSWLLGYMDP TEPSFVAAVI TIVFNPLFWN VVARWEQRTR KLSRAFGSPH LACYSLGICI 
LLLNILRSHC FTQAMMSQPK MEGLDNHTTY FLGLAFLGWG FVFVLSSFYA LGFTGTFLGD 
YFGILKESRV TTFPFSVLDN PMYWGSTANY LGWALMHASP TGLLLTVLVA IVYVVALLYE 
EPFTAEIYRQ KATRLHKRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pemt

Associated with

Other Information

Characterization of the murine phosphatidylethanolamine N-methyltransferase-2 gene. PubMed ID: 8978486

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase. PubMed ID: 9371769

Biochemical and evolutionary significance of phospholipid methylation. PubMed ID: 9765216

Plasma homocysteine is regulated by phospholipid methylation. PubMed ID: 12482759

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079