Penk | ENSMUSG00000045573 | NCBI 18619

Details for: Penk

Gene ID: 18619

Symbol: Penk

Ensembl ID: ENSMUSG00000045573

Description: preproenkephalin

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Metabolism of proteins
(R-MMU-392499)
Peptide ligand-binding receptors
(R-MMU-375276)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Aggressive behavior
(GO:0002118)
Axon
(GO:0030424)
Axon terminus
(GO:0043679)
Behavioral fear response
(GO:0001662)
Cell body fiber
(GO:0070852)
Chemical synaptic transmission
(GO:0007268)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Extracellular region
(GO:0005576)
G protein-coupled opioid receptor signaling pathway
(GO:0038003)
Locomotory behavior
(GO:0007626)
Locomotory exploration behavior
(GO:0035641)
Neuronal cell body
(GO:0043025)
Neuronal dense core vesicle lumen
(GO:0099013)
Neuropeptide signaling pathway
(GO:0007218)
Opioid peptide activity
(GO:0001515)
Opioid receptor binding
(GO:0031628)
Perikaryon
(GO:0043204)
Plasma membrane
(GO:0005886)
Positive regulation of behavioral fear response
(GO:2000987)
Receptor ligand activity
(GO:0048018)
Regulation of long-term synaptic depression
(GO:1900452)
Response to bacterium
(GO:0009617)
Sensory perception
(GO:0007600)
Sensory perception of pain
(GO:0019233)
Startle response
(GO:0001964)
Symmetric synapse
(GO:0032280)
Synaptic signaling via neuropeptide
(GO:0099538)
Synaptic vesicle lumen
(GO:0034592)
Transmission of nerve impulse
(GO:0019226)

Other Information

Proteins

Synenkephalin
Q3UXY8_MOUSE

Genular Protein ID: 822370837

Symbol: PENK_MOUSE

Name: Synenkephalin

UniProtKB Accession Codes:

P22005 Q68G73

Database IDs:

Citations:

PubMed ID: 2355920

Title: Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells.

PubMed ID: 2355920

DOI: 10.1128/mcb.10.7.3717-3726.1990

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2938259

Title: Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis.

PubMed ID: 2938259

DOI: 10.1126/science.2938259

PubMed ID: 6933569

Title: Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.

PubMed ID: 6933569

DOI: 10.1073/pnas.77.9.5512

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 35201898

Title: Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid.

PubMed ID: 35201898

DOI: 10.1126/science.abl5130

Sequence Information:

Length: 268
Mass: 31004
Checksum: 637F848B49F44013
Sequence:

MARFLRLCTW LLALGSCLLA TVQAECSQDC AKCSYRLVRP GDINFLACTL ECEGQLPSFK 
IWETCKDLLQ VSRPEFPWDN IDMYKDSSKQ DESHLLAKKY GGFMKRYGGF MKKMDELYPM 
EPEEEANGGE ILAKRYGGFM KKDADEGDTL ANSSDLLKEL LGTGDNRAKD SHQQESTNND 
EDMSKRYGGF MRSLKRSPQL EDEAKELQKR YGGFMRRVGR PEWWMDYQKR YGGFLKRFAE 
SLPSDEEGEN YSKEVPEIEK RYGGFMRF

Genular Protein ID: 1023915142

Symbol: Q3UXY8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UXY8

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 222
Mass: 25871
Checksum: B35D1244FEA75933
Sequence:

ACTLECEGQL PSFKIWETCK DLLQVSRPEF PWDNIDMYKD SSKQDESHLL AKKYGGFMKR 
YGGFMKKMDE LYPMEPEEEA NGGEILAKRY GGFMKKDADE GDTLANSSDL LKELLGTGDN 
RAKDSHQQES TNNDEDMSKR YGGFMRSLKR SPQLEDEAKE LQKRYGGFMR RVGRPEWWMD 
YQKRYGGFLK RFAESLPSDE EGENYSKEVP EIEKRYGGFM RF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Penk

Associated with

Other Information

Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells. PubMed ID: 2355920

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis. PubMed ID: 2938259

Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. PubMed ID: 6933569

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid. PubMed ID: 35201898

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073