Genular: Defining Cellular Identity and Function

Details for: Cfp

Gene ID: 18636

Symbol: Cfp

Ensembl ID: ENSMUSG00000001128

Description: complement factor properdin

Associated with

Activation of c3 and c5
(R-MMU-174577)
Alternative complement activation
(R-MMU-173736)
Complement cascade
(R-MMU-166658)
Immune system
(R-MMU-168256)
Initial triggering of complement
(R-MMU-166663)
Innate immune system
(R-MMU-168249)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
O-glycosylation of tsr domain-containing proteins
(R-MMU-5173214)
O-linked glycosylation
(R-MMU-5173105)
Post-translational protein modification
(R-MMU-597592)
Regulation of complement cascade
(R-MMU-977606)
Complement activation
(GO:0006956)
Complement activation, alternative pathway
(GO:0006957)
Cytoplasmic side of golgi membrane
(GO:0098548)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Positive regulation of immune response
(GO:0050778)
Positive regulation of opsonization
(GO:1903028)
Secretory granule
(GO:0030141)

Other Information

Proteins

Properdin

Genular Protein ID: 3808891045

Symbol: PROP_MOUSE

Name: Properdin

UniProtKB Accession Codes:

P11680 Q3TB98 Q3U779

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 3045564

Title: Properdin, the terminal complement components, thrombospondin and the circumsporozoite protein of malaria parasites contain similar sequence motifs.

PubMed ID: 3045564

DOI: 10.1038/335082a0

PubMed ID: 28264884

Title: Functional and structural insight into properdin control of complement alternative pathway amplification.

PubMed ID: 28264884

DOI: 10.15252/embj.201696173

Sequence Information:

Length: 464
Mass: 50327
Checksum: C787F5493042379A
Sequence:

MPAEMQAPQW LLLLLVILPA TGSDPVLCFT QYEESSGRCK GLLGRDIRVE DCCLNAAYAF 
QEHDGGLCQA CRSPQWSAWS LWGPCSVTCS EGSQLRHRRC VGRGGQCSEN VAPGTLEWQL 
QACEDQPCCP EMGGWSEWGP WGPCSVTCSK GTQIRQRVCD NPAPKCGGHC PGEAQQSQAC 
DTQKTCPTHG AWASWGPWSP CSGSCLGGAQ EPKETRSRSC SAPAPSHQPP GKPCSGPAYE 
HKACSGLPPC PVAGGWGPWS PLSPCSVTCG LGQTLEQRTC DHPAPRHGGP FCAGDATRNQ 
MCNKAVPCPV NGEWEAWGKW SDCSRLRMSI NCEGTPGQQS RSRSCGGRKF NGKPCAGKLQ 
DIRHCYNIHN CIMKGSWSQW STWSLCTPPC SPNATRVRQR LCTPLLPKYP PTVSMVEGQG 
EKNVTFWGTP RPLCEALQGQ KLVVEEKRSC LHVPVCKDPE EKKP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.