Genular: Defining Cellular Identity and Function

Details for: Pfkl

Gene ID: 18641

Symbol: Pfkl

Ensembl ID: ENSMUSG00000020277

Description: phosphofructokinase, liver, B-type

Associated with

Glucose metabolism
(R-MMU-70326)
Glycolysis
(R-MMU-70171)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Neutrophil degranulation
(R-MMU-6798695)
6-phosphofructokinase activity
(GO:0003872)
6-phosphofructokinase complex
(GO:0005945)
Amp binding
(GO:0016208)
Atp binding
(GO:0005524)
Canonical glycolysis
(GO:0061621)
Catalytic activity
(GO:0003824)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Fructose-6-phosphate binding
(GO:0070095)
Fructose 1,6-bisphosphate metabolic process
(GO:0030388)
Fructose 6-phosphate metabolic process
(GO:0006002)
Fructose binding
(GO:0070061)
Glycolytic process
(GO:0006096)
Glycolytic process through fructose-6-phosphate
(GO:0061615)
Identical protein binding
(GO:0042802)
Kinase activity
(GO:0016301)
Kinase binding
(GO:0019900)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Monosaccharide binding
(GO:0048029)
Negative regulation of insulin secretion
(GO:0046676)
Nucleotide binding
(GO:0000166)
Phosphorylation
(GO:0016310)
Response to glucose
(GO:0009749)
Transferase activity
(GO:0016740)

Other Information

Proteins

6-phosphofructokinase type B

Genular Protein ID: 2161326830

Symbol: PFKAL_MOUSE

Name: 6-phosphofructokinase type B

UniProtKB Accession Codes:

P12382 Q8VDX7

Database IDs:

Citations:

PubMed ID: 2969893

Title: Liver (B-type) phosphofructokinase mRNA. Cloning, structure, and expression.

PubMed ID: 2969893

DOI: 10.1016/s0021-9258(18)37848-7

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26194095

Title: Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.

PubMed ID: 26194095

DOI: 10.1038/ncomms8838

Sequence Information:

Length: 780
Mass: 85360
Checksum: 0C12E2C222020B7F
Sequence:

MATVDLEKLR MSGAGKAIGV LTSGGDAQGM NAAVRAVTRM GIYVGAKVFL IYEGYEGLVE 
GGENIKPANW LSVSNIIQLG GTIIGSARCK AFTTREGRLA AAYNLLQHGI TNLCVIGGDG 
SLTGANIFRN EWGSLLEELV KEGKISESTA QNYAHLTIAG LVGSIDNDFC GTDMTIGTDS 
ALHRIMEVID AITTTAQSHQ RTFVLEVMGR HCGYLALVSA LASGADWLFI PEAPPEDGWE 
NFMCERLGET RSRGSRLNII IIAEGAIDRH GKPISSSYVK DLVVQRLGFD TRVTVLGHVQ 
RGGTPSAFDR ILSSKMGMEA VMALLEATPD TPACVVSLSG NQSVRLPLME CVQVTKDVQK 
AMDEERFDEA IQLRGRSFEN NWKIYKLLAH QKVSKEKSNF SLAILNVGAP AAGMNAAVRS 
AVRTGISEGH TVYIVHDGFE GLAKGQVQEV GWHDVAGWLG RGGSMLGTKR TLPKPHLEAI 
VENLRTYNIH ALLVIGGFEA YEGVLQLVEA RGRYEELCIV MCVIPATISN NVPGTDFSLG 
SDTAVNAAME SCDRIKQSAS GTKRRVFIVE TMGGYCGYLA TVTGIAVGAD AAYVFEDPFN 
IHDLKANVEH MTEKMKTDIQ RGLVLRNEKC HEHYTTEFLY NLYSSEGRGV FDCRTNVLGH 
LQQGGAPTPF DRNYGTKLGV KAMLWVSEKL RDVYRKGRVF ANAPDSACVI GLRKKVVAFS 
PVTELKKETD FEHRMPREQW WLNLRLMLKM LAHYRISMAD YVSGELEHVT RRTLSIDKGF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pfkl

Associated with

Other Information

Liver (B-type) phosphofructokinase mRNA. Cloning, structure, and expression. PubMed ID: 2969893

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst. PubMed ID: 26194095