Genular: Defining Cellular Identity and Function

Details for: Pfkm

Gene ID: 18642

Symbol: Pfkm

Ensembl ID: ENSMUSG00000033065

Description: phosphofructokinase, muscle

Associated with

Glucose metabolism
(R-MMU-70326)
Glycolysis
(R-MMU-70171)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
6-phosphofructokinase activity
(GO:0003872)
6-phosphofructokinase complex
(GO:0005945)
Amp binding
(GO:0016208)
Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Canonical glycolysis
(GO:0061621)
Carbohydrate binding
(GO:0030246)
Carbohydrate phosphorylation
(GO:0046835)
Catalytic activity
(GO:0003824)
Cell projection
(GO:0042995)
Cilium
(GO:0005929)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Fructose-6-phosphate binding
(GO:0070095)
Fructose 1,6-bisphosphate metabolic process
(GO:0030388)
Fructose 6-phosphate metabolic process
(GO:0006002)
Fructose binding
(GO:0070061)
Glucose homeostasis
(GO:0042593)
Glycogen catabolic process
(GO:0005980)
Glycolysis from storage polysaccharide through glucose-1-phosphate
(GO:0093001)
Glycolytic process
(GO:0006096)
Glycolytic process through fructose-6-phosphate
(GO:0061615)
Identical protein binding
(GO:0042802)
Kinase activity
(GO:0016301)
Kinase binding
(GO:0019900)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Monosaccharide binding
(GO:0048029)
Motile cilium
(GO:0031514)
Muscle cell cellular homeostasis
(GO:0046716)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Phosphofructokinase activity
(GO:0008443)
Phosphorylation
(GO:0016310)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Sperm principal piece
(GO:0097228)
Transferase activity
(GO:0016740)

Other Information

Proteins

6-phosphofructokinase type A

Genular Protein ID: 2597927954

Symbol: PFKAM_MOUSE

Name: 6-phosphofructokinase type A

UniProtKB Accession Codes:

P47857 C8CMN5 C8CMN6 C8CMN7 O35513 Q543L1 Q9JK94

Database IDs:

Citations:

PubMed ID: 11137296

Title: Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.

PubMed ID: 11137296

DOI: 10.1016/s0378-1119(00)00463-7

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7980403

Title: Expression of mouse phosphofructokinase-M gene alternative transcripts: evidence for the conserved two-promoter system.

PubMed ID: 7980403

DOI: 10.1042/bj3030449

PubMed ID: 19889946

Title: Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5.

PubMed ID: 19889946

DOI: 10.1095/biolreprod.109.080580

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 780
Mass: 85269
Checksum: 7917C7AC108B25C7
Sequence:

MTHEEHHAAK TLGIGKAIAV LTSGGDAQGM NAAVRAVVRV GIFTGARVFF VHEGYQGLVD 
GGEHIREATW ESVSMMLQLG GTVIGSARCK DFREREGRLR AAHNLVKRGI TNLCVIGGDG 
SLTGADTFRS EWSDLLNDLQ KDGKITAEEA TKSSYLNIVG LVGSIDNDFC GTDMTIGTDS 
ALHRIVEIVD AITTTAQSHQ RTFVLEVMGR HCGYLALVTS LSCGADWVFI PECPPDDDWE 
EHLCRRLSET RTRGSRLNII IVAEGAIDKN GKPITSEDIK NLVVKRLGYD TRVTVLGHVQ 
RGGTPSAFDR ILGSRMGVEA VMALLEGTPD TPACVVSLSG NQAVRLPLME CVQVTKDVTK 
AMDEKRFDEA IKLRGRSFMN NWEVYKLLAH VRPPVSKGGL HTVAVMNVGA PAAGMNAAVR 
STVRIGLIQG NRVLVVHDGF EGLAKGQIEE AGWSYVGGWT GQGGSKLGTK RTLPKKNLEQ 
ISANITKFNI QGLVIIGGFE AYTGGLELME GRKQFDELCI PFVVIPATVS NNVPGSDFSI 
GADTALNTIC TTCDRIKQSA AGTKRRVFII ETMGGYCGYL ATMAGLAAGA DAAYIFEEPF 
TIRDLQVNVE HLVQKMKTTV KRGLVLRNEK CNENYTTDFI FNLYSEEGKG IFDSRKNVLG 
HMQQGGSPTP FDRNFATKMG AKAMNWMSGK IKESYRNGRI FANTPDSGCV LGMRKRALVF 
QPVTELKDQT DFEHRIPKEQ WWLKLRPILK ILAKYEIDLD TSDHAHLEHI SRKRSGEAAV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pfkm

Associated with

Other Information

Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene. PubMed ID: 11137296

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Expression of mouse phosphofructokinase-M gene alternative transcripts: evidence for the conserved two-promoter system. PubMed ID: 7980403