Genular: Defining Cellular Identity and Function

Details for: Pgk1

Gene ID: 18655

Symbol: Pgk1

Ensembl ID: ENSMUSG00000062070

Description: phosphoglycerate kinase 1

Associated with

Glucose metabolism
(R-MMU-70326)
Glycolysis
(R-MMU-70171)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Adp binding
(GO:0043531)
Atp binding
(GO:0005524)
Canonical glycolysis
(GO:0061621)
Cellular response to hypoxia
(GO:0071456)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular space
(GO:0005615)
Gluconeogenesis
(GO:0006094)
Glyceraldehyde-3-phosphate biosynthetic process
(GO:0046166)
Glycolytic process
(GO:0006096)
Kinase activity
(GO:0016301)
Membrane raft
(GO:0045121)
Negative regulation of angiogenesis
(GO:0016525)
Nucleotide binding
(GO:0000166)
Phosphoglycerate kinase activity
(GO:0004618)
Phosphorylation
(GO:0016310)
Plasminogen activation
(GO:0031639)
Protein-disulfide reductase (nad(p)) activity
(GO:0047134)
Protein binding
(GO:0005515)
Transferase activity
(GO:0016740)

Other Information

Proteins

Phosphoglycerate kinase 1

Genular Protein ID: 2323818504

Symbol: PGK1_MOUSE

Name: Phosphoglycerate kinase 1

UniProtKB Accession Codes:

P09411 Q3TPE6 Q3UKV8 Q5XJE7

Database IDs:

Citations:

PubMed ID: 3542714

Title: The nucleotide sequence of a cDNA clone containing the entire coding region for mouse X-chromosome-linked phosphoglycerate kinase.

PubMed ID: 3542714

DOI: 10.1016/0378-1119(86)90025-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3440520

Title: Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.

PubMed ID: 3440520

DOI: 10.1016/0378-1119(87)90214-9

PubMed ID: 2166582

Title: Selective activation of testis-specific genes in cultured rat spermatogenic cells.

PubMed ID: 2166582

DOI: 10.1016/0167-4781(90)90106-c

PubMed ID: 1975492

Title: Polymorphisms in the coding and noncoding regions of murine Pgk-1 alleles.

PubMed ID: 1975492

DOI: 10.1007/bf02401419

PubMed ID: 3525226

Title: Evolutionary conservation of the substrate-binding cleft of phosphoglycerate kinases.

PubMed ID: 3525226

DOI: 10.1016/0014-5793(86)80835-3

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 19759366

Title: Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice.

PubMed ID: 19759366

DOI: 10.1095/biolreprod.109.079699

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 417
Mass: 44550
Checksum: 5E2EE194FF9D8CEE
Sequence:

MSLSNKLTLD KLDVKGKRVV MRVDFNVPMK NNQITNNQRI KAAVPSIKFC LDNGAKSVVL 
MSHLGRPDGV PMPDKYSLEP VAAELKSLLG KDVLFLKDCV GPEVENACAN PAAGTVILLE 
NLRFHVEEEG KGKDASGNKV KAEPAKIDAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVN 
LPQKAGGFLM KKELNYFAKA LESPERPFLA ILGGAKVADK IQLINNMLDK VNEMIIGGGM 
AFTFLKVLNN MEIGTSLYDE EGAKIVKDLM SKAEKNGVKI TLPVDFVTAD KFDENAKTGQ 
ATVASGIPAG WMGLDCGTES SKKYAEAVGR AKQIVWNGPV GVFEWEAFAR GTKSLMDEVV 
KATSRGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSNV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pgk1

Associated with

Other Information

The nucleotide sequence of a cDNA clone containing the entire coding region for mouse X-chromosome-linked phosphoglycerate kinase. PubMed ID: 3542714

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter. PubMed ID: 3440520

Selective activation of testis-specific genes in cultured rat spermatogenic cells. PubMed ID: 2166582

Polymorphisms in the coding and noncoding regions of murine Pgk-1 alleles. PubMed ID: 1975492

Evolutionary conservation of the substrate-binding cleft of phosphoglycerate kinases. PubMed ID: 3525226

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. PubMed ID: 19759366

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337