Genular: Defining Cellular Identity and Function

Details for: Pgr

Gene ID: 18667

Symbol: Pgr

Ensembl ID: ENSMUSG00000031870

Description: progesterone receptor

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Esr-mediated signaling
(R-MMU-8939211)
Estrogen-dependent gene expression
(R-MMU-9018519)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-MMU-3371497)
Metabolism of proteins
(R-MMU-392499)
Nuclear receptor transcription pathway
(R-MMU-383280)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by nuclear receptors
(R-MMU-9006931)
Signal transduction
(R-MMU-162582)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of intracellular receptors
(R-MMU-4090294)
Atpase binding
(GO:0051117)
Axon
(GO:0030424)
Axon terminus
(GO:0043679)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna binding
(GO:0003677)
Enzyme binding
(GO:0019899)
Epithelial cell maturation
(GO:0002070)
Estrogen response element binding
(GO:0034056)
Female mating behavior
(GO:0060180)
Glandular epithelial cell maturation
(GO:0002071)
Hormone binding
(GO:0042562)
Identical protein binding
(GO:0042802)
Intracellular steroid hormone receptor signaling pathway
(GO:0030518)
Lipid binding
(GO:0008289)
Lung alveolus development
(GO:0048286)
Mammary gland development
(GO:0030879)
Metal ion binding
(GO:0046872)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of granulosa cell apoptotic process
(GO:1904709)
Nuclear receptor activity
(GO:0004879)
Nuclear steroid receptor activity
(GO:0003707)
Nucleic acid binding
(GO:0003676)
Nucleus
(GO:0005634)
Ovulation from ovarian follicle
(GO:0001542)
Paracrine signaling
(GO:0038001)
Perikaryon
(GO:0043204)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of smooth muscle cell migration
(GO:0014911)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Progesterone receptor signaling pathway
(GO:0050847)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to cocaine
(GO:0042220)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Signaling receptor binding
(GO:0005102)
Steroid binding
(GO:0005496)
Steroid hormone mediated signaling pathway
(GO:0043401)
Tertiary branching involved in mammary gland duct morphogenesis
(GO:0060748)
Transcription coactivator binding
(GO:0001223)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Progesterone receptor
Q8BW69_MOUSE

Genular Protein ID: 1183281660

Symbol: PRGR_MOUSE

Name: Progesterone receptor

UniProtKB Accession Codes:

Q00175 A6H6A5 E9QPW3

Database IDs:

Citations:

PubMed ID: 2069958

Title: Molecular cloning, sequence analyses, and expression of complementary DNA encoding murine progesterone receptor.

PubMed ID: 2069958

DOI: 10.1021/bi00242a029

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7802637

Title: Nucleic acid sequence and DNase hypersensitive sites of the 5' region of the mouse progesterone receptor gene.

PubMed ID: 7802637

DOI: 10.1006/bbrc.1994.2778

PubMed ID: 8603049

Title: Reproductive phenotpes of the progesterone receptor null mutant mouse.

PubMed ID: 8603049

DOI: 10.1016/0960-0760(95)00254-5

PubMed ID: 10976068

Title: Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform.

PubMed ID: 10976068

DOI: 10.1126/science.289.5485.1751

PubMed ID: 12672823

Title: Selective interactions of Kruppel-like factor 9/basic transcription element-binding protein with progesterone receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells.

PubMed ID: 12672823

DOI: 10.1074/jbc.m212098200

PubMed ID: 15044369

Title: Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle.

PubMed ID: 15044369

DOI: 10.1210/en.2004-0212

PubMed ID: 15878961

Title: Progesterone receptor isoforms A and B: temporal and spatial differences in expression during murine mammary gland development.

PubMed ID: 15878961

DOI: 10.1210/en.2005-0346

PubMed ID: 17003284

Title: Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LbetaT2 gonadotropes.

PubMed ID: 17003284

DOI: 10.1677/joe.1.06923

Sequence Information:

Length: 926
Mass: 98981
Checksum: E26DDDE9529996A7
Sequence:

MTELQAKDPQ VLHTSGASPS PPHIGSPLLA RLDSGPFQGS QHSDVSSVVS PIPISLDGLL 
FPRSCRGPEL PDGKTGDQQS LSDVEGAFSG VEATHREGGR NSRAPEKDSR LLDSVLDSLL 
TPSGTEQSHA SPPACEAITS WCLFGPELPE DPRSVPATKG LLSPLMSRPE IKAGDSSGTG 
AGQKVLPKGL SPPRQLLLPT SGSAHWPGAG VKPSPQPAAG EVEEDSGLET EGSAAPLLKS 
KPRALEGTGS GGGVAANAAS AAPGGVTLVP KEDSRFSAPR VSLEQDSPIA PGRSPLATTV 
VDFIHVPILP LNHALLAART RQLLEGDSYD GGATAQGPFA PPRGSPSAPS PPVPCGDFPD 
CTYPLEGDPK EDVFPLYGDF QTPGLKIKEE EEGADAAVRS PRPYLSAGAS SSTFPDFPLA 
PAPQRAPSSR PGEAAVAGGP SSAAVSPASS SGSALECILY KAEGAPPTQG SFAPLPCKPP 
AAGSCLLPRD SLPAAPATAA APAIYQPLGL NGLPQLGYQA AVLKDSLPQV YPPYLNYLRP 
DSEASQSPQY GFDSLPQKIC LICGDEASGC HYGVLTCGSC KVFFKRAMEG QHNYLCAGRN 
DCIVDKIRRK NCPACRLRKC CQAGMVLGGR KFKKFNKVRV MRTLDGVALP QSVGLPNESQ 
ALGQRITFSP NQEIQLVPPL INLLMSIEPD VVYAGHDNTK PDTSSSLLTS LNQLGERQLL 
SVVKWSKSLP GFRNLHIDDQ ITLIQYSWMS LMVFGLGWRS YKHVSGQMLY FAPDLILNEQ 
RMKELSFYSL CLTMWQIPQE FVKLQVTHEE FLCMKVLLLL NTIPLEGLRS QSQFEEMRSS 
YIRELIKAIG LRQKGVVPSS QRFYQLTKLL DSLHDLVKQL HLYCLNTFIQ SRTLAVEFPE 
MMSEVIAAQL PKILAGMVKP LLFHKK

Genular Protein ID: 127985292

Symbol: Q8BW69_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BW69

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 698
Mass: 75476
Checksum: E9009635FCC521EC
Sequence:

ETEGSAAPLL KSKPRALEGT GSGGGVAANA ASAAPGGVTL VPKEDSRFSA PRVSLEQDSP 
IAPGRSPLAT TVVDFIHVPI LPLNHALLAA RTRQLLEGDS YDGGATAQGP FAPPRGSPSA 
PSPPVPCGDF PDCTYPLEGD PKEDVFPLYG DFQTPGLKIK EEEEGADAAV RSPRPYLSAG 
ASSSTFPDFP LAPAPQRAPS SRPGEAAVAG GPSSAAVSPA SSSGSALECI LYKAEGAPPT 
QGSFAPLPCK PPAAGSCLLP RDSLPAAPAT AAAPAIYQPL GLNGLPQLGY QAAVLKDSLP 
QVYPPYLNYL RPDSEASQSP QYGFDSLPQK ICLICGDEAS GCHYGVLTCG SCKVFFKRAM 
EGQHNYLCAG RNDCIVDKIR RKNCPACRLR KCCQAGMVLG GRKFKKFNKV RVMRTLDGVA 
LPQSVGLPNE SQALGQRITF SPNQEIQLVP PLINLLMSIE PDVVYAGHDN TKPDTSSSLL 
TSLNQLGERQ LLSVVKWSKS LPGFRNLHID DQITLIQYSW MSLMVFGLGW RSYKHVSGQM 
LYFAPDLILN EQRMKELSFY SLCLTMWQIP QEFVKLQVTH EEFLCMKVLL LLNTIPLEGL 
RSQSQFEEMR SSYIRELIKA IGLRQKGVVP SSQRFYQLTK LLDSLHDLVK QLHLYCLNTF 
IQSRTLAVEF PEMMSEVIAA QLPKILAGMV KPLLFHKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pgr

Associated with

Other Information

Molecular cloning, sequence analyses, and expression of complementary DNA encoding murine progesterone receptor. PubMed ID: 2069958

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nucleic acid sequence and DNase hypersensitive sites of the 5' region of the mouse progesterone receptor gene. PubMed ID: 7802637

Reproductive phenotpes of the progesterone receptor null mutant mouse. PubMed ID: 8603049

Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. PubMed ID: 10976068

Selective interactions of Kruppel-like factor 9/basic transcription element-binding protein with progesterone receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells. PubMed ID: 12672823

Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle. PubMed ID: 15044369

Progesterone receptor isoforms A and B: temporal and spatial differences in expression during murine mammary gland development. PubMed ID: 15878961

Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LbetaT2 gonadotropes. PubMed ID: 17003284

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073