Genular: Defining Cellular Identity and Function

Details for: Abcb1b

Gene ID: 18669

Symbol: Abcb1b

Ensembl ID: ENSMUSG00000028970

Description: ATP-binding cassette, sub-family B member 1B

Associated with

Abc-type transporter activity
(GO:0140359)
Abc-type xenobiotic transporter activity
(GO:0008559)
Apical plasma membrane
(GO:0016324)
Atpase-coupled intramembrane lipid transporter activity
(GO:0140326)
Atpase-coupled transmembrane transporter activity
(GO:0042626)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Carboxylic acid transmembrane transport
(GO:1905039)
Carboxylic acid transmembrane transporter activity
(GO:0046943)
Cell surface
(GO:0009986)
Ceramide floppase activity
(GO:0099038)
Ceramide translocation
(GO:0099040)
Cytoplasm
(GO:0005737)
Efflux transmembrane transporter activity
(GO:0015562)
Establishment of endothelial blood-brain barrier
(GO:0014045)
Export across plasma membrane
(GO:0140115)
External side of apical plasma membrane
(GO:0098591)
Floppase activity
(GO:0140328)
G2/m transition of mitotic cell cycle
(GO:0000086)
Golgi membrane
(GO:0000139)
Intercellular canaliculus
(GO:0046581)
Lipid transport
(GO:0006869)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Nucleotide binding
(GO:0000166)
Phosphatidylcholine floppase activity
(GO:0090554)
Phosphatidylethanolamine flippase activity
(GO:0090555)
Phospholipid translocation
(GO:0045332)
Plasma membrane
(GO:0005886)
Positive regulation of anion channel activity
(GO:1901529)
Regulation of chloride transport
(GO:2001225)
Regulation of response to osmotic stress
(GO:0047484)
Response to xenobiotic stimulus
(GO:0009410)
Sertoli cell barrier remodeling
(GO:0061843)
Stem cell proliferation
(GO:0072089)
Transepithelial transport
(GO:0070633)
Transmembrane transport
(GO:0055085)
Ubiquitin protein ligase binding
(GO:0031625)
Xenobiotic detoxification by transmembrane export across the plasma membrane
(GO:1990961)
Xenobiotic transmembrane transporter activity
(GO:0042910)
Xenobiotic transport across blood-brain barrier
(GO:1990962)

Other Information

Proteins

ATP-binding cassette sub-family B member 1B

Genular Protein ID: 2307099276

Symbol: MDR1B_MOUSE

Name: ATP-binding cassette sub-family B member 1B

UniProtKB Accession Codes:

P06795

Database IDs:

Citations:

PubMed ID: 3768958

Title: Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.

PubMed ID: 3768958

DOI: 10.1016/0092-8674(86)90594-5

PubMed ID: 2570420

Title: Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

PubMed ID: 2570420

DOI: 10.1073/pnas.86.17.6488

PubMed ID: 2248681

Title: Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.

PubMed ID: 2248681

DOI: 10.1128/mcb.10.11.6036-6040.1990

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

Length: 1276
Mass: 140994
Checksum: 1804D0F011B0FF4E
Sequence:

MEFEENLKGR ADKNFSKMGK KSKKEKKEKK PAVGVFGMFR YADWLDKLCM ILGTLAAIIH 
GTLLPLLMLV FGNMTDSFTK AEASILPSIT NQSGPNSTLI ISNSSLEEEM AIYAYYYTGI 
GAGVLIVAYI QVSLWCLAAG RQIHKIRQKF FHAIMNQEIG WFDVHDVGEL NTRLTDDVSK 
INDGIGDKIG MFFQSITTFL AGFIIGFISG WKLTLVILAV SPLIGLSSAL WAKVLTSFTN 
KELQAYAKAG AVAEEVLAAI RTVIAFGGQQ KELERYNKNL EEAKNVGIKK AITASISIGI 
AYLLVYASYA LAFWYGTSLV LSNEYSIGEV LTVFFSILLG TFSIGHLAPN IEAFANARGA 
AFEIFKIIDN EPSIDSFSTK GYKPDSIMGN LEFKNVHFNY PSRSEVQILK GLNLKVKSGQ 
TVALVGNSGC GKSTTVQLMQ RLYDPLEGVV SIDGQDIRTI NVRYLREIIG VVSQEPVLFA 
TTIAENIRYG REDVTMDEIE KAVKEANAYD FIMKLPHQFD TLVGERGAQL SGGQKQRIAI 
ARALVRNPKI LLLDEATSAL DTESEAVVQA ALDKAREGRT TIVIAHRLST VRNADVIAGF 
DGGVIVEQGN HDELMREKGI YFKLVMTQTR GNEIEPGNNA YGSQSDTDAS ELTSEESKSP 
LIRRSIYRSV HRKQDQERRL SMKEAVDEDV PLVSFWRILN LNLSEWPYLL VGVLCAVING 
CIQPVFAIVF SRIVGVFSRD DDHETKRQNC NLFSLFFLVM GLISFVTYFF QGFTFGKAGE 
ILTKRVRYMV FKSMLRQDIS WFDDHKNSTG SLTTRLASDA SSVKGAMGAR LAVVTQNVAN 
LGTGVILSLV YGWQLTLLLV VIIPLIVLGG IIEMKLLSGQ ALKDKKQLEI SGKIATEAIE 
NFRTIVSLTR EQKFETMYAQ SLQVPYRNAM KKAHVFGITF SFTQAMMYFS YAACFRFGAY 
LVAQQLMTFE NVMLVFSAVV FGAMAAGNTS SFAPDYAKAK VSASHIIRII EKTPEIDSYS 
TEGLKPTLLE GNVKFNGVQF NYPTRPNIPV LQGLSLEVKK GQTLALVGSS GCGKSTVVQL 
LERFYDPMAG SVFLDGKEIK QLNVQWLRAH LGIVSQEPIL FDCSIAENIA YGDNSRAVSH 
EEIVRAAKEA NIHQFIDSLP DKYNTRVGDK GTQLSGGQKQ RIAIARALVR QPHILLLDEA 
TSALDTESEK VVQEALDKAR EGRTCIVIAH RLSTIQNADL IVVIENGKVK EHGTHQQLLA 
QKGIYFSMVQ AGAKRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Abcb1b

Associated with

Other Information

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. PubMed ID: 3768958

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene. PubMed ID: 2570420

Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1. PubMed ID: 2248681

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Database document:

PubMed ID: 3768958

PubMed ID: 2570420

PubMed ID: 2248681

PubMed ID: 19144319