Details for: Abcb4
Associated with
Other Information
Genular Protein ID: 1674442637
Symbol: MDR3_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3405218
Title: Cloning and characterization of a second member of the mouse mdr gene family.
PubMed ID: 3405218
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8759018
Title: De novo generation of simple sequence during gene amplification.
PubMed ID: 8759018
PubMed ID: 2471060
Title: The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.
PubMed ID: 2471060
PubMed ID: 1969609
Title: Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.
PubMed ID: 1969609
PubMed ID: 1990275
Title: Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes.
PubMed ID: 1990275
PubMed ID: 1381362
Title: mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies.
PubMed ID: 1381362
PubMed ID: 8106172
Title: Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.
PubMed ID: 8106172
PubMed ID: 7912658
Title: Phosphatidylcholine translocase: a physiological role for the mdr2 gene.
PubMed ID: 7912658
PubMed ID: 7592705
Title: Enhancement of Mdr2-mediated phosphatidylcholine translocation by the bile salt taurocholate. Implications for hepatic bile formation.
PubMed ID: 7592705
PubMed ID: 7814632
Title: Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.
PubMed ID: 7814632
DOI: 10.1172/jci117658
PubMed ID: 8615769
Title: Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
PubMed ID: 8615769
DOI: 10.1042/bj3140781
PubMed ID: 8725158
Title: Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein.
PubMed ID: 8725158
PubMed ID: 9366571
Title: Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy.
PubMed ID: 9366571
DOI: 10.1172/jci119799
PubMed ID: 12381268
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
PubMed ID: 12381268
DOI: 10.1042/bj20020981
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21820390
Title: Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity.
PubMed ID: 21820390
PubMed ID: 23468132
Title: Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes.
PubMed ID: 23468132
DOI: 10.1194/jlr.m032425
Sequence Information:
- Length: 1276
- Mass: 140377
- Checksum: 30BC72EDDFA4388C
- Sequence:
MDLEAARNGT ARRLDGDFEL GSISNQGREK KKKVNLIGLL TLFRYSDWQD KLFMFLGTLM AIAHGSGLPL MMIVFGEMTD KFVDNTGNFS LPVNFSLSML NPGRILEEEM TRYAYYYSGL GGGVLVAAYI QVSFWTLAAG RQIKKIRQKF FHAILRQEMG WFDIKGTTEL NTRLTDDVSK ISEGIGDKVG MFFQAIATFF AGFIVGFIRG WKLTLVIMAI SPILGLSTAV WAKILSTFSD KELAAYAKAG AVAEEALGAI RTVIAFGGQN KELERYQKHL ENAKKIGIKK AISANISMGI AFLLIYASYA LAFWYGSTLV ISKEYTIGNA MTVFFSILIG AFSVGQAAPC IDAFANARGA AYVIFDIIDN NPKIDSFSER GHKPDNIKGN LEFSDVHFSY PSRANIKILK GLNLKVKSGQ TVALVGNSGC GKSTTVQLLQ RLYDPTEGKI SIDGQDIRNF NVRCLREIIG VVSQEPVLFS TTIAENIRYG RGNVTMDEIE KAVKEANAYD FIMKLPQKFD TLVGDRGAQL SGGQKQRIAI ARALVRNPKI LLLDEATSAL DTESEAEVQA ALDKAREGRT TIVIAHRLST IRNADVIAGF EDGVIVEQGS HSELMKKEGI YFRLVNMQTA GSQILSEEFE VELSDEKAAG DVAPNGWKAR IFRNSTKKSL KSPHQNRLDE ETNELDANVP PVSFLKVLKL NKTEWPYFVV GTVCAIANGA LQPAFSIILS EMIAIFGPGD DAVKQQKCNM FSLVFLGLGV LSFFTFFLQG FTFGKAGEIL TTRLRSMAFK AMLRQDMSWF DDHKNSTGAL STRLATDAAQ VQGATGTRLA LIAQNTANLG TGIIISFIYG WQLTLLLLSV VPFIAVAGIV EMKMLAGNAK RDKKEMEAAG KIATEAIENI RTVVSLTQER KFESMYVEKL HGPYRNSVRK AHIYGITFSI SQAFMYFSYA GCFRFGSYLI VNGHMRFKDV ILVFSAIVLG AVALGHASSF APDYAKAKLS AAYLFSLFER QPLIDSYSGE GLWPDKFEGS VTFNEVVFNY PTRANVPVLQ GLSLEVKKGQ TLALVGSSGC GKSTVVQLLE RFYDPMAGSV LLDGQEAKKL NVQWLRAQLG IVSQEPILFD CSIAENIAYG DNSRVVPHDE IVRAAKEANI HPFIETLPQK YNTRVGDKGT QLSGGQKQRI AIARALIRQP RVLLLDEATS ALDTESEKVV QEALDKAREG RTCIVIAHRL STIQNADLIV VIENGKVKEH GTHQQLLAQK GIYFSMVNIQ AGTQNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.